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The map label for this gene is dmsC [H]

Identifier: 59713263

GI number: 59713263

Start: 86425

End: 87270

Strand: Reverse

Name: dmsC [H]

Synonym: VF_A0080

Alternate gene names: 59713263

Gene position: 87270-86425 (Counterclockwise)

Preceding gene: 59713264

Following gene: 59713262

Centisome position: 6.56

GC content: 38.3

Gene sequence:

>846_bases
ATGGCTTGGCATGAATGGCCGTTGATTTTATTCACGGTACTCTCTCAAACTGCTGTCGGCGCCTTCTTTGTATTAGGTTG
CGTAACTTTAAGTGGTAAATTATCACAAGATGAAGATACACGATTACACCGTAATATGTTCTTTATTTGGGTATTGATGG
GACTAGGGTTAATCGCATCAACAATGCACTTAGGTAGTCCACTTAGAGCATTTAATGCCCTTAATCGTGTTGGTAGCTCT
TGGTTATCAAATGAGATCTTTGCTTCTAGCTTATTCTTTGCCGCTGGTGGCTTTTACTGGCTATTAAAAGTGGTGAATAA
AGGCTCTGATGCATTGAAAAAAGGCTTATTGCTCATCTCTATGGTTATCGGTATTGGTTTTATGTATGCCATGATCAAGG
TGTATTTAATTAATACCGTACCAACATGGAACAGCATTTACACACCAATAATGTTCCTATTAACCATGGCAATATCTGGT
CTAGCATTTGCTCACACGTTATTGGTCGCGACTAATCATAAACACGCAGAGTTAAATAATGCTTTACCAGTATTTGCATC
AATTGCTCTTGCTATTAGTTTAATTGCAACGGTTAGCCAATTGATTGGTTTGAGCCATATCAGTTCTGCAATCATTGTTG
CATCTGACATCATACCTAACATGGCAACACTTCAAGTTTTACGCCTTGGCTTATTATTTGTTGGTTTTGTTCTGATGTTT
TCGCCACGTTTGATGTCAAGCCAACCAAAGCTTCCAGTAATATTATTAAGCTTTGTTTGTATTCTCGTGTCTGAACTTAT
CAACCGAGGCGTGTTTTATGGATTACACATGTCAGTAGGCATGTAA

Upstream 100 bases:

>100_bases
TCATTAATTACAAAACCAAACATTGTGATTAAACCAAACCGTAATGCTCGTCCAACAGATGATCAAACAGGTCATCTAGC
AAACCCTAAGGAGGTATAAC

Downstream 100 bases:

>100_bases
TTTAAACACCATATATCGGCTACTTTTAGGCAATAATGTTTCATGCATTATTGCCTTTTTTACATCTACTTCTTATCAAA
TACGAATACTAAAATAACCA

Product: dimethyl sulfoxide reductase, anaerobic, subunit C

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase anchor subunit [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MAWHEWPLILFTVLSQTAVGAFFVLGCVTLSGKLSQDEDTRLHRNMFFIWVLMGLGLIASTMHLGSPLRAFNALNRVGSS
WLSNEIFASSLFFAAGGFYWLLKVVNKGSDALKKGLLLISMVIGIGFMYAMIKVYLINTVPTWNSIYTPIMFLLTMAISG
LAFAHTLLVATNHKHAELNNALPVFASIALAISLIATVSQLIGLSHISSAIIVASDIIPNMATLQVLRLGLLFVGFVLMF
SPRLMSSQPKLPVILLSFVCILVSELINRGVFYGLHMSVGM

Sequences:

>Translated_281_residues
MAWHEWPLILFTVLSQTAVGAFFVLGCVTLSGKLSQDEDTRLHRNMFFIWVLMGLGLIASTMHLGSPLRAFNALNRVGSS
WLSNEIFASSLFFAAGGFYWLLKVVNKGSDALKKGLLLISMVIGIGFMYAMIKVYLINTVPTWNSIYTPIMFLLTMAISG
LAFAHTLLVATNHKHAELNNALPVFASIALAISLIATVSQLIGLSHISSAIIVASDIIPNMATLQVLRLGLLFVGFVLMF
SPRLMSSQPKLPVILLSFVCILVSELINRGVFYGLHMSVGM
>Mature_280_residues
AWHEWPLILFTVLSQTAVGAFFVLGCVTLSGKLSQDEDTRLHRNMFFIWVLMGLGLIASTMHLGSPLRAFNALNRVGSSW
LSNEIFASSLFFAAGGFYWLLKVVNKGSDALKKGLLLISMVIGIGFMYAMIKVYLINTVPTWNSIYTPIMFLLTMAISGL
AFAHTLLVATNHKHAELNNALPVFASIALAISLIATVSQLIGLSHISSAIIVASDIIPNMATLQVLRLGLLFVGFVLMFS
PRLMSSQPKLPVILLSFVCILVSELINRGVFYGLHMSVGM

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it [H]

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli ynfH [H]

Homologues:

Organism=Escherichia coli, GI1787123, Length=281, Percent_Identity=45.5516014234875, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1787873, Length=284, Percent_Identity=46.4788732394366, Blast_Score=211, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007059 [H]

Pfam domain/function: PF04976 DmsC [H]

EC number: NA

Molecular weight: Translated: 30710; Mature: 30579

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWHEWPLILFTVLSQTAVGAFFVLGCVTLSGKLSQDEDTRLHRNMFFIWVLMGLGLIAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TMHLGSPLRAFNALNRVGSSWLSNEIFASSLFFAAGGFYWLLKVVNKGSDALKKGLLLIS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
MVIGIGFMYAMIKVYLINTVPTWNSIYTPIMFLLTMAISGLAFAHTLLVATNHKHAELNN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
ALPVFASIALAISLIATVSQLIGLSHISSAIIVASDIIPNMATLQVLRLGLLFVGFVLMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SPRLMSSQPKLPVILLSFVCILVSELINRGVFYGLHMSVGM
CCHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHCCC
>Mature Secondary Structure 
AWHEWPLILFTVLSQTAVGAFFVLGCVTLSGKLSQDEDTRLHRNMFFIWVLMGLGLIAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TMHLGSPLRAFNALNRVGSSWLSNEIFASSLFFAAGGFYWLLKVVNKGSDALKKGLLLIS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
MVIGIGFMYAMIKVYLINTVPTWNSIYTPIMFLLTMAISGLAFAHTLLVATNHKHAELNN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
ALPVFASIALAISLIATVSQLIGLSHISSAIIVASDIIPNMATLQVLRLGLLFVGFVLMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SPRLMSSQPKLPVILLSFVCILVSELINRGVFYGLHMSVGM
CCHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 8429002; 2170332 [H]