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The map label for this gene is ftsY [H]

Identifier: 59713060

GI number: 59713060

Start: 2752524

End: 2753762

Strand: Reverse

Name: ftsY [H]

Synonym: VF_2453

Alternate gene names: 59713060

Gene position: 2753762-2752524 (Counterclockwise)

Preceding gene: 59713064

Following gene: 59713059

Centisome position: 95.04

GC content: 40.36

Gene sequence:

>1239_bases
ATGACAGGCAAAAAGAAACGCGGATTATTGTCTTGGTTAGGTTTTGGTGATGAAGAAAAAGCCGAACAACCAGCAGTAGA
ACAACAATCAGTAGAAGAAAATGCAGAAACGCTTTCTCAGGCTCCATCTAAAGATGATAGTGCCGTAGAGAGTGTAGTGG
AAGATGCAGAGCTTGAACAGCCTAAAGAAAGTGAGAAAGTAACGGTACAAGCTGAAGAAGCGACAGAAGCGGAAGAAGTT
GTTACTGAGAAAGAACCTGAAGCGGAATTAGAGGCTGAGCCTGTAATTAAAGTGGAAGAAGTTCAAGAAAAACCAACAGA
AAGTTTCTTTGCTCGTTTAAAGCGTAGTTTACAACGCACAAAAGAGAATATTGGCGCAGGATTCTTTGGTTTATTTAGCG
GTAAAAAAATTGATGATGAGCTGTTTGAAGAGCTTGAAGAACAGTTATTAATTGCCGATGTGGGAATGGACACGACAGTT
AGAATTATCGATAGTCTAACTGAAAAAGCAAGTAAGCAAGATCTTAAAGATGGTGAAGCATTATATGGTTTACTAAAAGA
AGAAATGGCTGAAATCTTAGCTAAAGTTGAACAACCATTAGAAATTAACGAAAAAAATATGCCACACGTGATTTTAATGG
TTGGCGTAAATGGTGTTGGTAAAACAACAACGATCGGTAAGTTAGCAAAACAATTCCAAAATGAAGGTAAGTCAGTCATG
TTGGCGGCGGGCGATACGTTCCGTGCAGCGGCTGTTGAGCAACTTCAGGTTTGGGGTCAGCGTAATGATGTTCCTGTTAT
TGCTCAACATACCGGCGCAGACAGTGCATCCGTTATTTACGATGCAATTGAAGCTGCACGAGCACGTAAAGTTGACGTTG
TTATTGCCGATACTGCAGGTCGTCTCCAAAATAAGAGTAACTTAATGGAGGAATTGCGTAAAATTGTTCGTGTAATGAAG
AAAATTGACCCATCAGCGCCGCATGAGATCATGTTAACTTTAGATGCGGGTACGGGCCAAAATGCCATTAGCCAAGCTAA
ATTGTTCAGTGATGTTGCTCCAGTAACTGGAATTACATTAACGAAATTGGACGGTACAGCAAAAGGTGGTGTTATTTTCT
CTATTGCGGATCAATTCCAAATTCCAATCCGTTTTATCGGTGTCGGTGAAGGCATTGATGATTTACGTCCATTTGTGGCG
CAAGATTTTATTGAAGCATTATTTAGTCGTGAGGAATAG

Upstream 100 bases:

>100_bases
GCGAGGTGAGTGTTGTTTACGTTTAACCATAGATTTTTTGACCGCTCAGAAAGTGATAGTATACGAGAAAATTGTACCAA
TTTAATTCTAGGATTTCCCA

Downstream 100 bases:

>100_bases
CGCGTGATTCGATTTCAGCAAGTGTCGAAAGCCTATCGAGGTGGTCGTCCAGCATTACAAAAAGTAAATTTTCATTTAAA
TAGAGGTGAAATGGCTTTTT

Product: fused Signal recognition particle (SRP) receptor: membrane binding protein/ protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTGKKKRGLLSWLGFGDEEKAEQPAVEQQSVEENAETLSQAPSKDDSAVESVVEDAELEQPKESEKVTVQAEEATEAEEV
VTEKEPEAELEAEPVIKVEEVQEKPTESFFARLKRSLQRTKENIGAGFFGLFSGKKIDDELFEELEEQLLIADVGMDTTV
RIIDSLTEKASKQDLKDGEALYGLLKEEMAEILAKVEQPLEINEKNMPHVILMVGVNGVGKTTTIGKLAKQFQNEGKSVM
LAAGDTFRAAAVEQLQVWGQRNDVPVIAQHTGADSASVIYDAIEAARARKVDVVIADTAGRLQNKSNLMEELRKIVRVMK
KIDPSAPHEIMLTLDAGTGQNAISQAKLFSDVAPVTGITLTKLDGTAKGGVIFSIADQFQIPIRFIGVGEGIDDLRPFVA
QDFIEALFSREE

Sequences:

>Translated_412_residues
MTGKKKRGLLSWLGFGDEEKAEQPAVEQQSVEENAETLSQAPSKDDSAVESVVEDAELEQPKESEKVTVQAEEATEAEEV
VTEKEPEAELEAEPVIKVEEVQEKPTESFFARLKRSLQRTKENIGAGFFGLFSGKKIDDELFEELEEQLLIADVGMDTTV
RIIDSLTEKASKQDLKDGEALYGLLKEEMAEILAKVEQPLEINEKNMPHVILMVGVNGVGKTTTIGKLAKQFQNEGKSVM
LAAGDTFRAAAVEQLQVWGQRNDVPVIAQHTGADSASVIYDAIEAARARKVDVVIADTAGRLQNKSNLMEELRKIVRVMK
KIDPSAPHEIMLTLDAGTGQNAISQAKLFSDVAPVTGITLTKLDGTAKGGVIFSIADQFQIPIRFIGVGEGIDDLRPFVA
QDFIEALFSREE
>Mature_411_residues
TGKKKRGLLSWLGFGDEEKAEQPAVEQQSVEENAETLSQAPSKDDSAVESVVEDAELEQPKESEKVTVQAEEATEAEEVV
TEKEPEAELEAEPVIKVEEVQEKPTESFFARLKRSLQRTKENIGAGFFGLFSGKKIDDELFEELEEQLLIADVGMDTTVR
IIDSLTEKASKQDLKDGEALYGLLKEEMAEILAKVEQPLEINEKNMPHVILMVGVNGVGKTTTIGKLAKQFQNEGKSVML
AAGDTFRAAAVEQLQVWGQRNDVPVIAQHTGADSASVIYDAIEAARARKVDVVIADTAGRLQNKSNLMEELRKIVRVMKK
IDPSAPHEIMLTLDAGTGQNAISQAKLFSDVAPVTGITLTKLDGTAKGGVIFSIADQFQIPIRFIGVGEGIDDLRPFVAQ
DFIEALFSREE

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=281, Percent_Identity=32.7402135231317, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI226371618, Length=200, Percent_Identity=37, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI295424842, Length=331, Percent_Identity=29.0030211480363, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI23308697, Length=331, Percent_Identity=29.0030211480363, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=34.2657342657343, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1789874, Length=328, Percent_Identity=76.219512195122, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1788963, Length=295, Percent_Identity=32.8813559322034, Blast_Score=144, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17539958, Length=200, Percent_Identity=32, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI193206261, Length=320, Percent_Identity=29.6875, Blast_Score=114, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6325345, Length=207, Percent_Identity=36.7149758454106, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320498, Length=231, Percent_Identity=31.1688311688312, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17647949, Length=284, Percent_Identity=30.6338028169014, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24641198, Length=301, Percent_Identity=28.2392026578073, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 45100; Mature: 44968

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKKKRGLLSWLGFGDEEKAEQPAVEQQSVEENAETLSQAPSKDDSAVESVVEDAELEQ
CCCCHHCCHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
PKESEKVTVQAEEATEAEEVVTEKEPEAELEAEPVIKVEEVQEKPTESFFARLKRSLQRT
CCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHH
KENIGAGFFGLFSGKKIDDELFEELEEQLLIADVGMDTTVRIIDSLTEKASKQDLKDGEA
HHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHH
LYGLLKEEMAEILAKVEQPLEINEKNMPHVILMVGVNGVGKTTTIGKLAKQFQNEGKSVM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEE
LAAGDTFRAAAVEQLQVWGQRNDVPVIAQHTGADSASVIYDAIEAARARKVDVVIADTAG
EECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCH
RLQNKSNLMEELRKIVRVMKKIDPSAPHEIMLTLDAGTGQNAISQAKLFSDVAPVTGITL
HHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEE
TKLDGTAKGGVIFSIADQFQIPIRFIGVGEGIDDLRPFVAQDFIEALFSREE
EECCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGKKKRGLLSWLGFGDEEKAEQPAVEQQSVEENAETLSQAPSKDDSAVESVVEDAELEQ
CCCHHCCHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
PKESEKVTVQAEEATEAEEVVTEKEPEAELEAEPVIKVEEVQEKPTESFFARLKRSLQRT
CCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHH
KENIGAGFFGLFSGKKIDDELFEELEEQLLIADVGMDTTVRIIDSLTEKASKQDLKDGEA
HHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHH
LYGLLKEEMAEILAKVEQPLEINEKNMPHVILMVGVNGVGKTTTIGKLAKQFQNEGKSVM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEE
LAAGDTFRAAAVEQLQVWGQRNDVPVIAQHTGADSASVIYDAIEAARARKVDVVIADTAG
EECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCH
RLQNKSNLMEELRKIVRVMKKIDPSAPHEIMLTLDAGTGQNAISQAKLFSDVAPVTGITL
HHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEE
TKLDGTAKGGVIFSIADQFQIPIRFIGVGEGIDDLRPFVAQDFIEALFSREE
EECCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]