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The map label for this gene is pssA [H]

Identifier: 59713035

GI number: 59713035

Start: 2713247

End: 2714599

Strand: Direct

Name: pssA [H]

Synonym: VF_2428

Alternate gene names: 59713035

Gene position: 2713247-2714599 (Clockwise)

Preceding gene: 59713034

Following gene: 59713039

Centisome position: 93.64

GC content: 34.29

Gene sequence:

>1353_bases
ATGAATTTGAAACCTCAAGAAAGTAAAGAACAGCTATCTAAGCTCCCAATGTTGTCTCAAAATCCTGAGAATATTAAGAT
TCTTCACACCGCTGCAGATTTTCGGTATGAACTTCTTAAACAAATAGAAAATGCACAACAACGCATTTATATAGTTGCAC
TTTACTTAGAAAATGATGATGCTGGTAGAGAAATCTTTACCGCTCTGTATGAAGCTAAACAGAAAAATCCGACACTAGAC
ATTAATGTTCTTGTTGATTGGCATCGAGCTCAAAGAGGACTTATCGGTGCTGAAAAGAGTGATGGTAACGCAGCGTTATA
TCGAGAATTCTCTGAAAAATATGAGCATTCAATAAATGTCCTTGGTGTTCCAGTAAGAAATAAAGAAGTTTTCGGCGTTT
TGCATCTAAAAGGTTTTATCTTTGACGACACCGTTGTTTATAGCGGCGCTAGCTTAAATGATGTATACCTTGCCCATAAA
GATAAATACCGCTTCGACAGATACCACGTTTTAAATAATGCTCTTCTTGCTAATTCAATGGTTTCATTTATTAAGAAAAC
ATTGATTGCTAGTCCTGCTGTAAATTGTTTATCACAACAAAATAGACCTGATACAAAATCCCTTAAGCCGGAAATTAAAG
AGTTAAGAAAGCAGCTCGGTTTAGCAAACTACCAATTTACGTCTCAAACAAGAAAAGAAGGTGAAGTTGGTATAACACCT
CTTGTTGGCTTAGGAAGAAAAGGGAATAAATTAAATAATTATATTCGCACTCTTTTAGCATCAGCCACATCTGAAATTAC
AATCTGTACTCCTTATTTCAACTTCCCTAAACCTATTGCAAAAGAACTAAAAAAAGCACTACGACGAGGAGTGAAAGTAA
CAATTATTGTCGGTGACAAAACTGCTAATGATTTCTACATTTCACCTGAAGAAGAATTTAAGACTATTGCAGGGTTACCA
TACCTATATGAGATAAACCTAAGAAACTTTGCTAAAGCTAATGAGACTTACATTGCTAGCAGACAATTATCTCTTAACTT
ATGGAAACATGAGAACAACAGTTTTCATCTAAAAGGTATGTGGGTAGATAAAGAATACACACTAATTACAGGTAGTAATC
TAAACCCAAGAGCCTGGAAACTAGATCTTGAGAATGGACTATTATTGCAGGATCCTGAACAGTTACTTGTAGATACGAAG
CAAGCTGAACTAGATGTAATCTTAGAACATACACAATTAATTGGTTCATACAAACAAGTAGACAAGCTTGATAGTTATCC
TGTTGAAGTAAAAAAATTAATCAAAAGAATTAAGCGAATTAAAGCAGATCATATACTGAATCAAATTCTATAA

Upstream 100 bases:

>100_bases
CCTTCTCTATAAAAAAACTAACAATTAGATATTACTCTCGGCAATACCCATGAAGTTTGCTAGAATCTATCCCCTTATAT
TGATTATTTAATGATTGGTT

Downstream 100 bases:

>100_bases
TTAAGTTATGGGTGTGCATTAATACAGTGCATACCCATTTTGATATTTCCCCGCCTCTATTCATCTAAAATTACACGTCC
TAGAGTCTCCATCATTTAAT

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNLKPQESKEQLSKLPMLSQNPENIKILHTAADFRYELLKQIENAQQRIYIVALYLENDDAGREIFTALYEAKQKNPTLD
INVLVDWHRAQRGLIGAEKSDGNAALYREFSEKYEHSINVLGVPVRNKEVFGVLHLKGFIFDDTVVYSGASLNDVYLAHK
DKYRFDRYHVLNNALLANSMVSFIKKTLIASPAVNCLSQQNRPDTKSLKPEIKELRKQLGLANYQFTSQTRKEGEVGITP
LVGLGRKGNKLNNYIRTLLASATSEITICTPYFNFPKPIAKELKKALRRGVKVTIIVGDKTANDFYISPEEEFKTIAGLP
YLYEINLRNFAKANETYIASRQLSLNLWKHENNSFHLKGMWVDKEYTLITGSNLNPRAWKLDLENGLLLQDPEQLLVDTK
QAELDVILEHTQLIGSYKQVDKLDSYPVEVKKLIKRIKRIKADHILNQIL

Sequences:

>Translated_450_residues
MNLKPQESKEQLSKLPMLSQNPENIKILHTAADFRYELLKQIENAQQRIYIVALYLENDDAGREIFTALYEAKQKNPTLD
INVLVDWHRAQRGLIGAEKSDGNAALYREFSEKYEHSINVLGVPVRNKEVFGVLHLKGFIFDDTVVYSGASLNDVYLAHK
DKYRFDRYHVLNNALLANSMVSFIKKTLIASPAVNCLSQQNRPDTKSLKPEIKELRKQLGLANYQFTSQTRKEGEVGITP
LVGLGRKGNKLNNYIRTLLASATSEITICTPYFNFPKPIAKELKKALRRGVKVTIIVGDKTANDFYISPEEEFKTIAGLP
YLYEINLRNFAKANETYIASRQLSLNLWKHENNSFHLKGMWVDKEYTLITGSNLNPRAWKLDLENGLLLQDPEQLLVDTK
QAELDVILEHTQLIGSYKQVDKLDSYPVEVKKLIKRIKRIKADHILNQIL
>Mature_450_residues
MNLKPQESKEQLSKLPMLSQNPENIKILHTAADFRYELLKQIENAQQRIYIVALYLENDDAGREIFTALYEAKQKNPTLD
INVLVDWHRAQRGLIGAEKSDGNAALYREFSEKYEHSINVLGVPVRNKEVFGVLHLKGFIFDDTVVYSGASLNDVYLAHK
DKYRFDRYHVLNNALLANSMVSFIKKTLIASPAVNCLSQQNRPDTKSLKPEIKELRKQLGLANYQFTSQTRKEGEVGITP
LVGLGRKGNKLNNYIRTLLASATSEITICTPYFNFPKPIAKELKKALRRGVKVTIIVGDKTANDFYISPEEEFKTIAGLP
YLYEINLRNFAKANETYIASRQLSLNLWKHENNSFHLKGMWVDKEYTLITGSNLNPRAWKLDLENGLLLQDPEQLLVDTK
QAELDVILEHTQLIGSYKQVDKLDSYPVEVKKLIKRIKRIKADHILNQIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=429, Percent_Identity=48.4848484848485, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI25143331, Length=438, Percent_Identity=23.2876712328767, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6319842, Length=319, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28572961, Length=432, Percent_Identity=24.7685185185185, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 51519; Mature: 51519

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKPQESKEQLSKLPMLSQNPENIKILHTAADFRYELLKQIENAQQRIYIVALYLENDD
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
AGREIFTALYEAKQKNPTLDINVLVDWHRAQRGLIGAEKSDGNAALYREFSEKYEHSINV
CHHHHHHHHHHHHCCCCCEEEEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
LGVPVRNKEVFGVLHLKGFIFDDTVVYSGASLNDVYLAHKDKYRFDRYHVLNNALLANSM
EEEEECCCCEEEEEEEEEEEEECEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
VSFIKKTLIASPAVNCLSQQNRPDTKSLKPEIKELRKQLGLANYQFTSQTRKEGEVGITP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHCCCCCCCCCC
LVGLGRKGNKLNNYIRTLLASATSEITICTPYFNFPKPIAKELKKALRRGVKVTIIVGDK
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCC
TANDFYISPEEEFKTIAGLPYLYEINLRNFAKANETYIASRQLSLNLWKHENNSFHLKGM
CCCCCEECCHHHHHHHCCCCEEEEECCHHHCCCCCEEEEEEEEEEEEEEECCCCEEEEEE
WVDKEYTLITGSNLNPRAWKLDLENGLLLQDPEQLLVDTKQAELDVILEHTQLIGSYKQV
EECCEEEEEECCCCCCCEEEEECCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DKLDSYPVEVKKLIKRIKRIKADHILNQIL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLKPQESKEQLSKLPMLSQNPENIKILHTAADFRYELLKQIENAQQRIYIVALYLENDD
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
AGREIFTALYEAKQKNPTLDINVLVDWHRAQRGLIGAEKSDGNAALYREFSEKYEHSINV
CHHHHHHHHHHHHCCCCCEEEEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
LGVPVRNKEVFGVLHLKGFIFDDTVVYSGASLNDVYLAHKDKYRFDRYHVLNNALLANSM
EEEEECCCCEEEEEEEEEEEEECEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
VSFIKKTLIASPAVNCLSQQNRPDTKSLKPEIKELRKQLGLANYQFTSQTRKEGEVGITP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHCCCCCCCCCC
LVGLGRKGNKLNNYIRTLLASATSEITICTPYFNFPKPIAKELKKALRRGVKVTIIVGDK
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCC
TANDFYISPEEEFKTIAGLPYLYEINLRNFAKANETYIASRQLSLNLWKHENNSFHLKGM
CCCCCEECCHHHHHHHCCCCEEEEECCHHHCCCCCEEEEEEEEEEEEEEECCCCEEEEEE
WVDKEYTLITGSNLNPRAWKLDLENGLLLQDPEQLLVDTKQAELDVILEHTQLIGSYKQV
EECCEEEEEECCCCCCCEEEEECCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DKLDSYPVEVKKLIKRIKRIKADHILNQIL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]