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The map label for this gene is zntR [H]

Identifier: 59713000

GI number: 59713000

Start: 2680264

End: 2680683

Strand: Reverse

Name: zntR [H]

Synonym: VF_2393

Alternate gene names: 59713000

Gene position: 2680683-2680264 (Counterclockwise)

Preceding gene: 59713003

Following gene: 59712999

Centisome position: 92.52

GC content: 35.24

Gene sequence:

>420_bases
ATGTATTTAATTGGTGAGTTAGCTAAACAATGTAATGTTACGAGCGACACATTACGTTTTTACGAAAAAAATGGTCTTCT
TGTGCCATCAGGAAGAAGTAGCAGCGGTTACCGTTTGTATAATGATGACAATCTGGCTCAAATTCGTTTTATTCTAAAGG
CGAAGCAACTTGGTCTCGCATTGGATGAAATTCAAGAATTATTAGCGATTAGATTAGAAGCAACAAAACACAGTTGTGCA
GAAGTAAAAGCCATTACTCAATCTAAGTTAAATATTATTGACGAAAAGATCGCTCAACTAACAGACATTCGCCTTGCATT
AAAGAGTATAAATGATGCTTGTTGTGGTCATGTTGATGAAGATGCTTCTCACTGTTCTATTCTTTCTGCGTTAGCTGAAT
TAGAAGAGAAAAAAGACTAA

Upstream 100 bases:

>100_bases
CAAAAAAGCTCGCGCAATCGATTGCATTCGCAAAAAAAGATGCCCTTTTTCTTTAAAAAGAATCAAAATAGAGTGAAGTA
AAGAGGAATAAGAAGCAAAA

Downstream 100 bases:

>100_bases
ATAGTTGTGCGTGTTTATTAAAGAAGTTGATAAAATAGTCGATAACTACAATAGACCAATATGAGCGAAAGTTAGGTGAG
AGCCGATTAATGGAAAAACA

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MYLIGELAKQCNVTSDTLRFYEKNGLLVPSGRSSSGYRLYNDDNLAQIRFILKAKQLGLALDEIQELLAIRLEATKHSCA
EVKAITQSKLNIIDEKIAQLTDIRLALKSINDACCGHVDEDASHCSILSALAELEEKKD

Sequences:

>Translated_139_residues
MYLIGELAKQCNVTSDTLRFYEKNGLLVPSGRSSSGYRLYNDDNLAQIRFILKAKQLGLALDEIQELLAIRLEATKHSCA
EVKAITQSKLNIIDEKIAQLTDIRLALKSINDACCGHVDEDASHCSILSALAELEEKKD
>Mature_139_residues
MYLIGELAKQCNVTSDTLRFYEKNGLLVPSGRSSSGYRLYNDDNLAQIRFILKAKQLGLALDEIQELLAIRLEATKHSCA
EVKAITQSKLNIIDEKIAQLTDIRLALKSINDACCGHVDEDASHCSILSALAELEEKKD

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=133, Percent_Identity=43.609022556391, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1786695, Length=129, Percent_Identity=34.8837209302326, Blast_Score=80, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15424; Mature: 15424

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLIGELAKQCNVTSDTLRFYEKNGLLVPSGRSSSGYRLYNDDNLAQIRFILKAKQLGLA
CCHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
LDEIQELLAIRLEATKHSCAEVKAITQSKLNIIDEKIAQLTDIRLALKSINDACCGHVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DASHCSILSALAELEEKKD
CHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYLIGELAKQCNVTSDTLRFYEKNGLLVPSGRSSSGYRLYNDDNLAQIRFILKAKQLGLA
CCHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
LDEIQELLAIRLEATKHSCAEVKAITQSKLNIIDEKIAQLTDIRLALKSINDACCGHVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DASHCSILSALAELEEKKD
CHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]