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The map label for this gene is caiE [C]

Identifier: 59712976

GI number: 59712976

Start: 2656704

End: 2657264

Strand: Direct

Name: caiE [C]

Synonym: VF_2369

Alternate gene names: 59712976

Gene position: 2656704-2657264 (Clockwise)

Preceding gene: 59712975

Following gene: 172087768

Centisome position: 91.69

GC content: 39.75

Gene sequence:

>561_bases
ATGTTAAGAAAAAATCCTACAGGACATATGCCTCAGGTATCAGAAACGGCTTTTATCGATCCTACTGCGATCATTTGTGG
AAAAGTGATTATTCAAGATAACGTGTTTATTGGACCTTATGCGGTGATTCGTGCCGATGAAGTCAATGAATATGGAGATA
TGGAAGCCATCATAATTAAACGCGATACCAATATTCAAGATGGCGTAGTTATCCACTCAAAAGCGGGAGCTGCAGTCACT
ATCGGTGAGCGTTCATCCATAGCTCACAGATCCATCATACATGGGCCAAGTGAAGTCAGTGATGATGTTTTTATTGGGTT
TAATTCAGTCGTATTTAATGCTGTTATTGGTAAAGGTTGTGTCATTCGTCATAACTGTGTCATCGATGGTCTAGATCTAC
CAGAAAATTTTCACGTACCACCAATGACAAACATCGGTTCAGATTTCGATTTGAATAGCATTTCAAAGGTCCCTCCAGAA
TATTCTGCATTTTCAGAGTCTGTAGTTTCAGCCAATCATACTCTCGTTCAAGGTTATCGGAGAATTGCCAATGAGCTCTA
A

Upstream 100 bases:

>100_bases
AATTAAAGACTAGGCACAACCTTAATTTAGATAATAATGAAAATTAAATAACACGGCTGTAAACAGAGTACCTATTTAAA
TATTAAAAAGAGAAATCAAT

Downstream 100 bases:

>100_bases
TAAACACCCTATCATCGGCGTTCCTACCAATATTATTACTGGCTTTCTCGGCGTAGGAAAAACCTCGACTATTCTGAACC
TTATGGCAAATAAACCAAAA

Product: carbonic anhydrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MLRKNPTGHMPQVSETAFIDPTAIICGKVIIQDNVFIGPYAVIRADEVNEYGDMEAIIIKRDTNIQDGVVIHSKAGAAVT
IGERSSIAHRSIIHGPSEVSDDVFIGFNSVVFNAVIGKGCVIRHNCVIDGLDLPENFHVPPMTNIGSDFDLNSISKVPPE
YSAFSESVVSANHTLVQGYRRIANEL

Sequences:

>Translated_186_residues
MLRKNPTGHMPQVSETAFIDPTAIICGKVIIQDNVFIGPYAVIRADEVNEYGDMEAIIIKRDTNIQDGVVIHSKAGAAVT
IGERSSIAHRSIIHGPSEVSDDVFIGFNSVVFNAVIGKGCVIRHNCVIDGLDLPENFHVPPMTNIGSDFDLNSISKVPPE
YSAFSESVVSANHTLVQGYRRIANEL
>Mature_186_residues
MLRKNPTGHMPQVSETAFIDPTAIICGKVIIQDNVFIGPYAVIRADEVNEYGDMEAIIIKRDTNIQDGVVIHSKAGAAVT
IGERSSIAHRSIIHGPSEVSDDVFIGFNSVVFNAVIGKGCVIRHNCVIDGLDLPENFHVPPMTNIGSDFDLNSISKVPPE
YSAFSESVVSANHTLVQGYRRIANEL

Specific function: Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation [H]

COG id: COG0663

COG function: function code R; Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI87081681, Length=116, Percent_Identity=36.2068965517241, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787667, Length=132, Percent_Identity=32.5757575757576, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082240, Length=129, Percent_Identity=29.4573643410853, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 20187; Mature: 20187

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKNPTGHMPQVSETAFIDPTAIICGKVIIQDNVFIGPYAVIRADEVNEYGDMEAIIIK
CCCCCCCCCCCCCCCCEECCCHHHHHCEEEEECCEEECCEEEEEECCCCCCCCEEEEEEE
RDTNIQDGVVIHSKAGAAVTIGERSSIAHRSIIHGPSEVSDDVFIGFNSVVFNAVIGKGC
ECCCCCCCEEEECCCCCEEEECCCCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCE
VIRHNCVIDGLDLPENFHVPPMTNIGSDFDLNSISKVPPEYSAFSESVVSANHTLVQGYR
EEEECEEEECCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHCCHHHHHHHH
RIANEL
HHHHCC
>Mature Secondary Structure
MLRKNPTGHMPQVSETAFIDPTAIICGKVIIQDNVFIGPYAVIRADEVNEYGDMEAIIIK
CCCCCCCCCCCCCCCCEECCCHHHHHCEEEEECCEEECCEEEEEECCCCCCCCEEEEEEE
RDTNIQDGVVIHSKAGAAVTIGERSSIAHRSIIHGPSEVSDDVFIGFNSVVFNAVIGKGC
ECCCCCCCEEEECCCCCEEEECCCCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCE
VIRHNCVIDGLDLPENFHVPPMTNIGSDFDLNSISKVPPEYSAFSESVVSANHTLVQGYR
EEEECEEEECCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHCCHHHHHHHH
RIANEL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041719; 8665839; 10924115 [H]