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The map label for this gene is znuB2 [H]

Identifier: 59712975

GI number: 59712975

Start: 2655829

End: 2656650

Strand: Direct

Name: znuB2 [H]

Synonym: VF_2368

Alternate gene names: 59712975

Gene position: 2655829-2656650 (Clockwise)

Preceding gene: 59712974

Following gene: 59712976

Centisome position: 91.66

GC content: 43.67

Gene sequence:

>822_bases
ATGTTGGATGATTTTCTTTGGCGAGCCACATTAGCAGGCGTTGGTGTAACATTAGCAGCCGCCCCTCTTGGCTGCTTTAT
CGTTTGGCGTCGTATGGCATATTTTGGTGATGCGACTGCTCATGCTTCTATGTTAGGCATTGCGTTATCTCTTGCTCTTT
CGCTTCCAATTTTGCCTAGTGTTCTTTTTATTGCGCTAATTATGGCGATTACTGTATCTAAGTTCAGTGGACGTAGTTAC
GCAATGGACACTCTACTTGGGGTGATGGCACATTCTGCGTTAGCAATTGGTCTGGTGGCCGTATCTTTTTTGTCCGGAAT
ACGCCTTGATCTTATGGCTTATTTGTTCGGCGATATTCTTGCTGTAAGTAAGATGGATCTGTTCATTATCTGGGGAGGGG
CTTTATTTATCATTGGTTTAATTAGGTTTCGTTGGTCTGGTTTGTTGCTATCAATACTCGATAAAGACTTGGCACTGGCC
AGTAACTTCTCACCTAAACGTGAACAACTCATTCTAACCATTGCCCTTGCCATCGTGGTCGCCGTTGCCATCAAAGTTGT
AGGGGTGCTGTTAATCGTCGCCATGCTCATCATTCCAGCAGCAGCCGCTCGTCCGTTCAGCCAAACTCCCGAAATGATGG
TAGTACTTGCAGCCTTAATCGGCAGTAGTTCTAGCATTTTAGGGTTACGAGCCTCTTATCTATTCGACACTCCAACAGGC
CCAACAATAGTTTGTATTGCTACAGGGTTGTTCATCACATCAAGTTTGATACGGAAATTAAAGACTAGGCACAACCTTAA
TTTAGATAATAATGAAAATTAA

Upstream 100 bases:

>100_bases
TCACCAGAATATAAAGTGTTATTTGGTCTCGACGATAACGATGTTTTAGGCGTATACCGCCACAAGGCGGCTTCCAATCA
ATTTAATGGGAGTGTACTGA

Downstream 100 bases:

>100_bases
ATAACACGGCTGTAAACAGAGTACCTATTTAAATATTAAAAAGAGAAATCAATATGTTAAGAAAAAATCCTACAGGACAT
ATGCCTCAGGTATCAGAAAC

Product: high-affinity zinc uptake system membrane protein ZnuB2

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLDDFLWRATLAGVGVTLAAAPLGCFIVWRRMAYFGDATAHASMLGIALSLALSLPILPSVLFIALIMAITVSKFSGRSY
AMDTLLGVMAHSALAIGLVAVSFLSGIRLDLMAYLFGDILAVSKMDLFIIWGGALFIIGLIRFRWSGLLLSILDKDLALA
SNFSPKREQLILTIALAIVVAVAIKVVGVLLIVAMLIIPAAAARPFSQTPEMMVVLAALIGSSSSILGLRASYLFDTPTG
PTIVCIATGLFITSSLIRKLKTRHNLNLDNNEN

Sequences:

>Translated_273_residues
MLDDFLWRATLAGVGVTLAAAPLGCFIVWRRMAYFGDATAHASMLGIALSLALSLPILPSVLFIALIMAITVSKFSGRSY
AMDTLLGVMAHSALAIGLVAVSFLSGIRLDLMAYLFGDILAVSKMDLFIIWGGALFIIGLIRFRWSGLLLSILDKDLALA
SNFSPKREQLILTIALAIVVAVAIKVVGVLLIVAMLIIPAAAARPFSQTPEMMVVLAALIGSSSSILGLRASYLFDTPTG
PTIVCIATGLFITSSLIRKLKTRHNLNLDNNEN
>Mature_273_residues
MLDDFLWRATLAGVGVTLAAAPLGCFIVWRRMAYFGDATAHASMLGIALSLALSLPILPSVLFIALIMAITVSKFSGRSY
AMDTLLGVMAHSALAIGLVAVSFLSGIRLDLMAYLFGDILAVSKMDLFIIWGGALFIIGLIRFRWSGLLLSILDKDLALA
SNFSPKREQLILTIALAIVVAVAIKVVGVLLIVAMLIIPAAAARPFSQTPEMMVVLAALIGSSSSILGLRASYLFDTPTG
PTIVCIATGLFITSSLIRKLKTRHNLNLDNNEN

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=257, Percent_Identity=44.7470817120623, Blast_Score=203, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 29108; Mature: 29108

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDDFLWRATLAGVGVTLAAAPLGCFIVWRRMAYFGDATAHASMLGIALSLALSLPILPS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VLFIALIMAITVSKFSGRSYAMDTLLGVMAHSALAIGLVAVSFLSGIRLDLMAYLFGDIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSKMDLFIIWGGALFIIGLIRFRWSGLLLSILDKDLALASNFSPKREQLILTIALAIVV
HHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AVAIKVVGVLLIVAMLIIPAAAARPFSQTPEMMVVLAALIGSSSSILGLRASYLFDTPTG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHEEECCCC
PTIVCIATGLFITSSLIRKLKTRHNLNLDNNEN
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLDDFLWRATLAGVGVTLAAAPLGCFIVWRRMAYFGDATAHASMLGIALSLALSLPILPS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VLFIALIMAITVSKFSGRSYAMDTLLGVMAHSALAIGLVAVSFLSGIRLDLMAYLFGDIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSKMDLFIIWGGALFIIGLIRFRWSGLLLSILDKDLALASNFSPKREQLILTIALAIVV
HHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AVAIKVVGVLLIVAMLIIPAAAARPFSQTPEMMVVLAALIGSSSSILGLRASYLFDTPTG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHEEECCCC
PTIVCIATGLFITSSLIRKLKTRHNLNLDNNEN
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 2842314; 7984428; 9680209 [H]