Click here to switch to the map view.

The map label for this gene is argE [H]

Identifier: 59712914

GI number: 59712914

Start: 2592105

End: 2593241

Strand: Direct

Name: argE [H]

Synonym: VF_2307

Alternate gene names: 59712914

Gene position: 2592105-2593241 (Clockwise)

Preceding gene: 59712909

Following gene: 59712915

Centisome position: 89.46

GC content: 40.19

Gene sequence:

>1137_bases
ATGAAATTTCCGGAATTTAAAGATTATTATCAACAGCTCATTTCAACCTCTTCAATAAGCTCGACCGACTCAAGTTGGGA
TGAAGGCAATGCAGAAGTCATAAATAAACTTGCACAATGGTGCGAAGATCTTGGGTGTGAAGTTGAGATTGAAGAAATTG
AAAAAGGTAAACTCAATCTATTGGCAAAATTAGGGTCTGGTGAAGGTGGGTTATTATTAGCAGGTCATACCGATACGGTC
CCATACGATGAAGGCCGTTGGAATTATGAACCACACGCTTTAACTGAAGCTAACGATCGATTTTATGGATTAGGCACCGC
AGACATGAAAGGTTTCTTTGCTTTTATTCTAGAAGCCATTAAAAACATTAATTGGAAAGATCAGTCTAAACCTCTCTATA
TTCTGGCAACTTGTGATGAAGAAACCACCATGCTTGGTGCTCGTCACTTTGCATCAAATACTAAAATTCAACCAGATTAT
TGCATTATCGGTGAGCCAACTAGCCTAAAACCGATCCGTGGACATAAAGGACATGTCGCTAATGCCATTCGAGTAACAGG
TAAATCTGGACACTCTTCCGATCCCGCTCATGGTGTAAATGCCTTAGAGATCATGAACGAGATCATGTTCGCTCTCATGA
CATTAAAAAATAAATTAGTTAAGGAATATCATAACCCTGGTTTCTCTATTCCTTACCCGACACTTAATCTTGGTCATATT
CATGGAGGGGACAGCCCAAACCGTATTTGTGGCTGTTGTGAACTGCATTATGATGTTCGTCCACTGCCGGGGATCAGCTT
AGATGGTCTTGATAATATGCTTCGTGATGCTCTAAAAGAGATTGAAGCAAAATGGCCTGGACGTATTGATATTACCCCAC
TTCATGAACCTATTCCTGGTTATGAATGTAGCGCCGATAGTCCGATAGTAACGAGCACTGCTGACATTTGTGGGCAAGAT
GTAGAAACCGTGAACTACTGTACTGAAGCGCCTTTTTTACAAGATCTTTGTCCTACATTAGTACTTGGCCCCGGCTCTAT
TGAACAAGCTCACCAACCTGATGAGTATTTAGCTTTTTCTTTTATAGACCCAACCATCAGTATATTAAGCAAATTAATGT
ACAAACACTGTTTTTAG

Upstream 100 bases:

>100_bases
CACTCAAACTCAACTAAATTGTATTTTTATTCACTTAATGTGATTTAATATGTGTTTTACAGAATTCTCTCTTTTGTGTC
AACAGTGGATGTATGAATAA

Downstream 100 bases:

>100_bases
GCTGAAATAAATTTACAAAACTCGTCAATATGAAAAGTAAGGTTCGATGATCTACGGCAAATTAGCGTTCAAAAAACCAA
CAAATATTCACCAATATTTG

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKFPEFKDYYQQLISTSSISSTDSSWDEGNAEVINKLAQWCEDLGCEVEIEEIEKGKLNLLAKLGSGEGGLLLAGHTDTV
PYDEGRWNYEPHALTEANDRFYGLGTADMKGFFAFILEAIKNINWKDQSKPLYILATCDEETTMLGARHFASNTKIQPDY
CIIGEPTSLKPIRGHKGHVANAIRVTGKSGHSSDPAHGVNALEIMNEIMFALMTLKNKLVKEYHNPGFSIPYPTLNLGHI
HGGDSPNRICGCCELHYDVRPLPGISLDGLDNMLRDALKEIEAKWPGRIDITPLHEPIPGYECSADSPIVTSTADICGQD
VETVNYCTEAPFLQDLCPTLVLGPGSIEQAHQPDEYLAFSFIDPTISILSKLMYKHCF

Sequences:

>Translated_378_residues
MKFPEFKDYYQQLISTSSISSTDSSWDEGNAEVINKLAQWCEDLGCEVEIEEIEKGKLNLLAKLGSGEGGLLLAGHTDTV
PYDEGRWNYEPHALTEANDRFYGLGTADMKGFFAFILEAIKNINWKDQSKPLYILATCDEETTMLGARHFASNTKIQPDY
CIIGEPTSLKPIRGHKGHVANAIRVTGKSGHSSDPAHGVNALEIMNEIMFALMTLKNKLVKEYHNPGFSIPYPTLNLGHI
HGGDSPNRICGCCELHYDVRPLPGISLDGLDNMLRDALKEIEAKWPGRIDITPLHEPIPGYECSADSPIVTSTADICGQD
VETVNYCTEAPFLQDLCPTLVLGPGSIEQAHQPDEYLAFSFIDPTISILSKLMYKHCF
>Mature_378_residues
MKFPEFKDYYQQLISTSSISSTDSSWDEGNAEVINKLAQWCEDLGCEVEIEEIEKGKLNLLAKLGSGEGGLLLAGHTDTV
PYDEGRWNYEPHALTEANDRFYGLGTADMKGFFAFILEAIKNINWKDQSKPLYILATCDEETTMLGARHFASNTKIQPDY
CIIGEPTSLKPIRGHKGHVANAIRVTGKSGHSSDPAHGVNALEIMNEIMFALMTLKNKLVKEYHNPGFSIPYPTLNLGHI
HGGDSPNRICGCCELHYDVRPLPGISLDGLDNMLRDALKEIEAKWPGRIDITPLHEPIPGYECSADSPIVTSTADICGQD
VETVNYCTEAPFLQDLCPTLVLGPGSIEQAHQPDEYLAFSFIDPTISILSKLMYKHCF

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=379, Percent_Identity=56.2005277044855, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI1789236, Length=352, Percent_Identity=24.4318181818182, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788816, Length=253, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17551016, Length=316, Percent_Identity=25.6329113924051, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41841; Mature: 41841

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPEFKDYYQQLISTSSISSTDSSWDEGNAEVINKLAQWCEDLGCEVEIEEIEKGKLNL
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCEEE
LAKLGSGEGGLLLAGHTDTVPYDEGRWNYEPHALTEANDRFYGLGTADMKGFFAFILEAI
EEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
KNINWKDQSKPLYILATCDEETTMLGARHFASNTKIQPDYCIIGEPTSLKPIRGHKGHVA
HCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCC
NAIRVTGKSGHSSDPAHGVNALEIMNEIMFALMTLKNKLVKEYHNPGFSIPYPTLNLGHI
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECEE
HGGDSPNRICGCCELHYDVRPLPGISLDGLDNMLRDALKEIEAKWPGRIDITPLHEPIPG
CCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
YECSADSPIVTSTADICGQDVETVNYCTEAPFLQDLCPTLVLGPGSIEQAHQPDEYLAFS
CCCCCCCCEEECCHHHCCCCHHHHHHHHCCCHHHHHCHHEEECCCCCCCCCCCCHHEEEE
FIDPTISILSKLMYKHCF
ECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFPEFKDYYQQLISTSSISSTDSSWDEGNAEVINKLAQWCEDLGCEVEIEEIEKGKLNL
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCEEE
LAKLGSGEGGLLLAGHTDTVPYDEGRWNYEPHALTEANDRFYGLGTADMKGFFAFILEAI
EEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
KNINWKDQSKPLYILATCDEETTMLGARHFASNTKIQPDYCIIGEPTSLKPIRGHKGHVA
HCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCC
NAIRVTGKSGHSSDPAHGVNALEIMNEIMFALMTLKNKLVKEYHNPGFSIPYPTLNLGHI
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECEE
HGGDSPNRICGCCELHYDVRPLPGISLDGLDNMLRDALKEIEAKWPGRIDITPLHEPIPG
CCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
YECSADSPIVTSTADICGQDVETVNYCTEAPFLQDLCPTLVLGPGSIEQAHQPDEYLAFS
CCCCCCCCEEECCHHHCCCCHHHHHHHHCCCHHHHHCHHEEECCCCCCCCCCCCHHEEEE
FIDPTISILSKLMYKHCF
ECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA