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The map label for this gene is oxyR [H]

Identifier: 59712906

GI number: 59712906

Start: 2582767

End: 2583666

Strand: Reverse

Name: oxyR [H]

Synonym: VF_2299

Alternate gene names: 59712906

Gene position: 2583666-2582767 (Counterclockwise)

Preceding gene: 59712910

Following gene: 59712904

Centisome position: 89.17

GC content: 41.33

Gene sequence:

>900_bases
ATGAATATCCGAGATTTTGAGTACTTGGTCGCACTTGCTGAGCATAAACACTTTCGTAAAGCGGCAGAGTCTTGTTTTGT
TAGTCAGCCGACATTAAGTGGACAAATCAAGAAGTTAGAAGATGAAGTTGGTTTGGCTTTATTAGAGAGAACCAGTCGCA
AAGTCTTGTTCACTGAGGCTGGGTTACAGTTAGTCGAGCAAGCGAAAAAGATCTTACTTGAAGTAAAACGCTTTTCTGAA
CTTGCCAATCAACAAGGTAAGGAAATGACAGGCCCGTTGCATTTAGGGTTTATACCTACCGTTGGGCCTTATGTGTTGCC
ATGGATTGTTCCAACATTGAAAGCACAGTTCCCAGATTTAAATTTATACCTTCATGAAGCGCAGACGCATCAATTAGTGA
AAATGCTAGAAGAGGGGAAAATTGACTGTATGATTTTGGCTTCTGTGGAAGAGACCAATATGTTTATCGAGGTTCCTGTT
TACGATGAGCCTATGGTACTTGCTGTGCCTAAAGATCATAAATGGGCAAAAGAAGTGTCGATTGATATGTCTCGTTTGAG
TGGTGAATCGGTTCTTATGTTAGGAGATGGTCACTGCTTACGAGATCAAGCCTTAGGTTTTTGTTTTGCTGCAGGGGCTA
AAGATGATGATCATTTTAAAGCAACTAGTTTAGAAACGTTACGTAATATGGTCGCTGCCGGCGGGGGGATTACATTAATG
CCATACTTGTCGGTACCAAAAGAAAAAGAGCGTGATGGTGTGTGTTATTTACCTGCTCAAGATCCTGTCCCTCATCGTCA
AATCGTTTTAGCTTATCGCCCTGGTTCACCACTAAGAGCGCGATATGAGTCACTGGCTAAAGAGATTGAGAATAAAATGT
CTAATGTTATTCGTAGCTAA

Upstream 100 bases:

>100_bases
ACTTGATAGTTCTAATCGTTTGGTGTTATCGTTTCAATCGTTAAAATCTATCAATCAATTTATTGATAATAAAGTGATAA
AGCTTACGGGAGTTTAATAC

Downstream 100 bases:

>100_bases
ATTAAGCTTATAAAAAAGGCACGCTAGATATGTAGCGTGCCTTTTTATTAAAGTGATTTTAAGGGATTAGAACAGGCTTT
CGTCTTCCATTCCGTCACCA

Product: DNA-binding transcriptional regulator OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNIRDFEYLVALAEHKHFRKAAESCFVSQPTLSGQIKKLEDEVGLALLERTSRKVLFTEAGLQLVEQAKKILLEVKRFSE
LANQQGKEMTGPLHLGFIPTVGPYVLPWIVPTLKAQFPDLNLYLHEAQTHQLVKMLEEGKIDCMILASVEETNMFIEVPV
YDEPMVLAVPKDHKWAKEVSIDMSRLSGESVLMLGDGHCLRDQALGFCFAAGAKDDDHFKATSLETLRNMVAAGGGITLM
PYLSVPKEKERDGVCYLPAQDPVPHRQIVLAYRPGSPLRARYESLAKEIENKMSNVIRS

Sequences:

>Translated_299_residues
MNIRDFEYLVALAEHKHFRKAAESCFVSQPTLSGQIKKLEDEVGLALLERTSRKVLFTEAGLQLVEQAKKILLEVKRFSE
LANQQGKEMTGPLHLGFIPTVGPYVLPWIVPTLKAQFPDLNLYLHEAQTHQLVKMLEEGKIDCMILASVEETNMFIEVPV
YDEPMVLAVPKDHKWAKEVSIDMSRLSGESVLMLGDGHCLRDQALGFCFAAGAKDDDHFKATSLETLRNMVAAGGGITLM
PYLSVPKEKERDGVCYLPAQDPVPHRQIVLAYRPGSPLRARYESLAKEIENKMSNVIRS
>Mature_299_residues
MNIRDFEYLVALAEHKHFRKAAESCFVSQPTLSGQIKKLEDEVGLALLERTSRKVLFTEAGLQLVEQAKKILLEVKRFSE
LANQQGKEMTGPLHLGFIPTVGPYVLPWIVPTLKAQFPDLNLYLHEAQTHQLVKMLEEGKIDCMILASVEETNMFIEVPV
YDEPMVLAVPKDHKWAKEVSIDMSRLSGESVLMLGDGHCLRDQALGFCFAAGAKDDDHFKATSLETLRNMVAAGGGITLM
PYLSVPKEKERDGVCYLPAQDPVPHRQIVLAYRPGSPLRARYESLAKEIENKMSNVIRS

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=295, Percent_Identity=66.4406779661017, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI157672245, Length=276, Percent_Identity=26.4492753623188, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788887, Length=287, Percent_Identity=28.2229965156794, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787879, Length=247, Percent_Identity=29.1497975708502, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI145693105, Length=297, Percent_Identity=28.2828282828283, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788748, Length=300, Percent_Identity=25, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787530, Length=285, Percent_Identity=22.4561403508772, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI2367136, Length=264, Percent_Identity=23.8636363636364, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790208, Length=267, Percent_Identity=26.9662921348315, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=25.7142857142857, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788626, Length=271, Percent_Identity=26.1992619926199, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=24.5901639344262, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=25.5172413793103, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33518; Mature: 33518

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRDFEYLVALAEHKHFRKAAESCFVSQPTLSGQIKKLEDEVGLALLERTSRKVLFTEA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHH
GLQLVEQAKKILLEVKRFSELANQQGKEMTGPLHLGFIPTVGPYVLPWIVPTLKAQFPDL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCC
NLYLHEAQTHQLVKMLEEGKIDCMILASVEETNMFIEVPVYDEPMVLAVPKDHKWAKEVS
EEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCEEEEECCCCCHHHHHH
IDMSRLSGESVLMLGDGHCLRDQALGFCFAAGAKDDDHFKATSLETLRNMVAAGGGITLM
HHHHHCCCCEEEEEECCCCHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
PYLSVPKEKERDGVCYLPAQDPVPHRQIVLAYRPGSPLRARYESLAKEIENKMSNVIRS
EECCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIRDFEYLVALAEHKHFRKAAESCFVSQPTLSGQIKKLEDEVGLALLERTSRKVLFTEA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHH
GLQLVEQAKKILLEVKRFSELANQQGKEMTGPLHLGFIPTVGPYVLPWIVPTLKAQFPDL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCC
NLYLHEAQTHQLVKMLEEGKIDCMILASVEETNMFIEVPVYDEPMVLAVPKDHKWAKEVS
EEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCEEEEECCCCCHHHHHH
IDMSRLSGESVLMLGDGHCLRDQALGFCFAAGAKDDDHFKATSLETLRNMVAAGGGITLM
HHHHHCCCCEEEEEECCCCHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
PYLSVPKEKERDGVCYLPAQDPVPHRQIVLAYRPGSPLRARYESLAKEIENKMSNVIRS
EECCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA