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The map label for this gene is aroB [H]

Identifier: 59712898

GI number: 59712898

Start: 2573783

End: 2574871

Strand: Reverse

Name: aroB [H]

Synonym: VF_2291

Alternate gene names: 59712898

Gene position: 2574871-2573783 (Counterclockwise)

Preceding gene: 59712899

Following gene: 59712897

Centisome position: 88.86

GC content: 39.85

Gene sequence:

>1089_bases
ATGGAAACGATTCATGTAGATTTAGCAGAACGTAGCTATCCCATCTCTATCGGCGCCGAGTTGTTTTGCAACCCGGCGCA
TTTTTCATCTGTAATACCTGCCAAAAAACGTGTTGTCGTTATCAGTAATGTGACGGTTGCGCCTCTGTATGCCCAACAAA
TTATTGACACTTTAAACACCTTTGAATGCCAAGTATCACTGCTTGAATTAGACGATGGTGAACAATATAAAAATTTAGAT
ACTTTTAACCAAATACTTACTTTCTTACTTGAAGAAAATCACAGTCGTGATGTGACGATTGTTGCTTTAGGTGGTGGTGT
TGTTGGTGATGTTGTTGGTTTTGCTTCTGCTTGCTATCAACGAGGTGTCGACTTTATTCAAATACCTACCACGCTTCTTT
CTCAGGTTGATTCATCTGTTGGCGGCAAGACGGCCATTAATCACCCTCTTGGTAAGAATATGGTTGGTGCTTTCTATCAA
CCAAAAGCCGTTATTATTGATATAAACTGCCTTAAAACATTACCTGAGCGTGAATTTGCGGCAGGAATGGCTGAGGTGAT
TAAATATGGCATCATTGTTGATAGAGAGTTTTTTGATTGGCTTGATGAGAATATGGATAAATTATACGCGTTAGATCATG
ATGCGTTGATTTATGCGATTTCACGTTGTTGTCAAATCAAAGCGGATGTCGTTGCTAAAGATGAAAAAGAATCAGGAATG
CGTGCACTCTTGAACCTAGGTCATACTTTTGGTCATGCGATTGAAGCTGAAATGGGTTACGGTAATTGGCTTCATGGTGA
AGCAGTTTCTGCCGGAACTGTTATGGCAGCGGTAACCGCGCAAAAAGAGGGATTAATTTCCCAATCTGATGTAGAGCGCA
TTTGTTCTATTTTAGAAAAAGCGAAGTTACCATTAAAAGCACCAAAAGAAATGACAGTAGATGCGTTTATGAAGCACATG
ATGCGTGATAAGAAAGTCTTATCAGGTAAATTACGTTTGGTTCTACCAACTTCCATTGGTAGCTCTGAAGTAGTTACAGG
TGTTTCTGAGAGCGTACTTGCTGAAGTAATTGAGCAATGTAAGGCATAG

Upstream 100 bases:

>100_bases
TACCGATGATCAAAGTGCAAAAGTAGTTGCAAACCAAATCATTCAAATGCTTGAAGAGCGTTAATTTAAGCAATTAATAG
ATATAAAGTGGGAACGAATC

Downstream 100 bases:

>100_bases
AAAAAGATATGAGTATTGGTCATGATTTAACTGTTTTGGAATTAGAAAGTCAAATTGATGTGTTATCTCGCATTCAGTTT
GTTTCTCGTTTTGGTTCTAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNTFECQVSLLELDDGEQYKNLD
TFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQRGVDFIQIPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQ
PKAVIIDINCLKTLPEREFAAGMAEVIKYGIIVDREFFDWLDENMDKLYALDHDALIYAISRCCQIKADVVAKDEKESGM
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQSDVERICSILEKAKLPLKAPKEMTVDAFMKHM
MRDKKVLSGKLRLVLPTSIGSSEVVTGVSESVLAEVIEQCKA

Sequences:

>Translated_362_residues
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNTFECQVSLLELDDGEQYKNLD
TFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQRGVDFIQIPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQ
PKAVIIDINCLKTLPEREFAAGMAEVIKYGIIVDREFFDWLDENMDKLYALDHDALIYAISRCCQIKADVVAKDEKESGM
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQSDVERICSILEKAKLPLKAPKEMTVDAFMKHM
MRDKKVLSGKLRLVLPTSIGSSEVVTGVSESVLAEVIEQCKA
>Mature_362_residues
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNTFECQVSLLELDDGEQYKNLD
TFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQRGVDFIQIPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQ
PKAVIIDINCLKTLPEREFAAGMAEVIKYGIIVDREFFDWLDENMDKLYALDHDALIYAISRCCQIKADVVAKDEKESGM
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQSDVERICSILEKAKLPLKAPKEMTVDAFMKHM
MRDKKVLSGKLRLVLPTSIGSSEVVTGVSESVLAEVIEQCKA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=364, Percent_Identity=58.7912087912088, Blast_Score=444, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6320332, Length=338, Percent_Identity=38.1656804733728, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39556; Mature: 39556

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNT
CCEEEEECCCCCCCEEECHHHEECHHHHHHCCCCCCEEEEEECCEEHHHHHHHHHHHHCC
FECQVSLLELDDGEQYKNLDTFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQ
CEEEEEEEECCCCCHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RGVDFIQIPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQPKAVIIDINCLKTLPEREFA
CCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCEEEEEEHHHHCCCCHHHH
AGMAEVIKYGIIVDREFFDWLDENMDKLYALDHDALIYAISRCCQIKADVVAKDEKESGM
HHHHHHHHHHHEECHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQSDVERICSILEK
HHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHEEHHHHCCCCCHHHHHHHHHHHHH
AKLPLKAPKEMTVDAFMKHMMRDKKVLSGKLRLVLPTSIGSSEVVTGVSESVLAEVIEQC
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHH
KA
CC
>Mature Secondary Structure
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNT
CCEEEEECCCCCCCEEECHHHEECHHHHHHCCCCCCEEEEEECCEEHHHHHHHHHHHHCC
FECQVSLLELDDGEQYKNLDTFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQ
CEEEEEEEECCCCCHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RGVDFIQIPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQPKAVIIDINCLKTLPEREFA
CCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCEEEEEEHHHHCCCCHHHH
AGMAEVIKYGIIVDREFFDWLDENMDKLYALDHDALIYAISRCCQIKADVVAKDEKESGM
HHHHHHHHHHHEECHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQSDVERICSILEK
HHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHEEHHHHCCCCCHHHHHHHHHHHHH
AKLPLKAPKEMTVDAFMKHMMRDKKVLSGKLRLVLPTSIGSSEVVTGVSESVLAEVIEQC
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHH
KA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA