Click here to switch to the map view.

The map label for this gene is hslV [H]

Identifier: 59712884

GI number: 59712884

Start: 2559754

End: 2560335

Strand: Direct

Name: hslV [H]

Synonym: VF_2277

Alternate gene names: 59712884

Gene position: 2559754-2560335 (Clockwise)

Preceding gene: 59712883

Following gene: 59712885

Centisome position: 88.34

GC content: 41.92

Gene sequence:

>582_bases
ATGAAGATGGTCGTCTTGCTTTCATTTATTGACGCCATCGAAAAAGAGGTTTTACTCGTGACTACAATTGTTTCTGTACG
CCGTGAAGGCAAAGTCGTGGTTGCTGGCGATGGCCAAGCATCTCAAGGCGATATGATCGCAAAAGGCAACGTAAAAAAAG
TACGTCGCTTATACAATGACTCAGTATTAGTTGGTTTTGCTGGTAGCACAGCTGATGCATTTATTCTGTTCGACCTGTGT
GAACGTAAGCTAGAAATGCATCAAGGTAATCTAACAAAAGCCGCAGTAGAACTAGCAAAAGAATGGCGTAGTGACCGAGC
ATTACGTCGTCTTGAAGCAATGTTAATTGTTGCAGATAAAACAACGTCATTAATCATCAGTGGTACAGGTGATCTAATCA
ATGCTGATAATGACTTACTAACTATTGGTTCTGGTGGTTACTTTGCTCGTTCTGCAGCAACAGCGCTGTTAGAAAATACC
GATTTAGACGCTCGCGAAATTGCAACTAAAGCACTGACTATTGCTGGCGATATCGATGTATACACCAACCACAACCACAC
AGTTGAAGAACTGAACGCTTAA

Upstream 100 bases:

>100_bases
ACATCACATATTTAATAAAAGGAGCGCATTGAGTGCTCCTTTTTTCTATCCATTCATCTTGAAAAGCGTCTTACCTTCCC
CCATTACAATAGTAATAATC

Downstream 100 bases:

>100_bases
CCAAGAATAAGGAATTACCATGTCTGAGATGACTCCTCGTGAAATTGTACACGAATTAGATAGCCATATTATTGGTCAAG
ATAAAGCAAAACGTTCAGTT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKMVVLLSFIDAIEKEVLLVTTIVSVRREGKVVVAGDGQASQGDMIAKGNVKKVRRLYNDSVLVGFAGSTADAFILFDLC
ERKLEMHQGNLTKAAVELAKEWRSDRALRRLEAMLIVADKTTSLIISGTGDLINADNDLLTIGSGGYFARSAATALLENT
DLDAREIATKALTIAGDIDVYTNHNHTVEELNA

Sequences:

>Translated_193_residues
MKMVVLLSFIDAIEKEVLLVTTIVSVRREGKVVVAGDGQASQGDMIAKGNVKKVRRLYNDSVLVGFAGSTADAFILFDLC
ERKLEMHQGNLTKAAVELAKEWRSDRALRRLEAMLIVADKTTSLIISGTGDLINADNDLLTIGSGGYFARSAATALLENT
DLDAREIATKALTIAGDIDVYTNHNHTVEELNA
>Mature_193_residues
MKMVVLLSFIDAIEKEVLLVTTIVSVRREGKVVVAGDGQASQGDMIAKGNVKKVRRLYNDSVLVGFAGSTADAFILFDLC
ERKLEMHQGNLTKAAVELAKEWRSDRALRRLEAMLIVADKTTSLIISGTGDLINADNDLLTIGSGGYFARSAATALLENT
DLDAREIATKALTIAGDIDVYTNHNHTVEELNA

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=173, Percent_Identity=71.0982658959538, Blast_Score=255, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 20894; Mature: 20894

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMVVLLSFIDAIEKEVLLVTTIVSVRREGKVVVAGDGQASQGDMIAKGNVKKVRRLYND
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCHHHHHHHHCC
SVLVGFAGSTADAFILFDLCERKLEMHQGNLTKAAVELAKEWRSDRALRRLEAMLIVADK
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
TTSLIISGTGDLINADNDLLTIGSGGYFARSAATALLENTDLDAREIATKALTIAGDIDV
CEEEEEECCCCEEECCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHEEEEECEEE
YTNHNHTVEELNA
EECCCCCHHHCCC
>Mature Secondary Structure
MKMVVLLSFIDAIEKEVLLVTTIVSVRREGKVVVAGDGQASQGDMIAKGNVKKVRRLYND
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCHHHHHHHHCC
SVLVGFAGSTADAFILFDLCERKLEMHQGNLTKAAVELAKEWRSDRALRRLEAMLIVADK
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
TTSLIISGTGDLINADNDLLTIGSGGYFARSAATALLENTDLDAREIATKALTIAGDIDV
CEEEEEECCCCEEECCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHEEEEECEEE
YTNHNHTVEELNA
EECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA