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The map label for this gene is cpdA [H]

Identifier: 59712837

GI number: 59712837

Start: 2502887

End: 2503711

Strand: Reverse

Name: cpdA [H]

Synonym: VF_2230

Alternate gene names: 59712837

Gene position: 2503711-2502887 (Counterclockwise)

Preceding gene: 59712838

Following gene: 59712836

Centisome position: 86.41

GC content: 40.12

Gene sequence:

>825_bases
TTGCTCTCTGAAACATTACTTAATGAAGAAAGCGATTCGATTCGCTTGTTACAGATAACAGATACCCATTTGTTTGCGCC
AGAAGATGGTGCATTACTTGGCGTACCTACACGAAAAAGCTTTCAAAGCGTTGTAGAACAAGTACTACAGCGAACTCCTG
ATTTTGATGCCATTCTTGCTACGGGTGATATTTCTCAAGATCACACCGTTGAATCTTATCAGCACTTTGTTAAGGGAATA
ATACCTCTAAAAAAGCCTTGTTTTTGGCTTCCTGGTAATCATGACTATAAGCCAAGCATGGGCGGTGTTTTGCCTTCTCC
ACAAATTAGTGCGTGTGAACATTTACTTATTGGTCAGCATTGGCAAGTGATTATTCTGGACAGCCAAGTTGTAGGCGTTC
CTCATGGTGCATTATCTGATGAGCAGTTAACATTATTAGATAACGCATTATCTCAACACCCTCAACGTCATTCATTGGTA
TTATTGCATCACCATCCATTGCCTGCAGGAAGCGCTTGGCTAGATCAGCATCAACTTAAAGAAAGTGAGCAATTTTGGTC
TGTCTTAGCAAAACATCATAATGTGAATGGAATTGTTTGCGGGCATATTCATCAAGAATTAGACCGAGTTGTTAACGGTA
TTCGCTTATTAGCTACACCATCTACTTGTGTGCAATTTCTTCCTGATTCAGATGATTTTGCTTTGGATTCTCAAGCTCCA
GGTTGGAGAACATTAGACTTATTACCAAATGGTGATATTGAAACGCAGGTATATCGACTTAAAGATTGTGACTTTTCAGC
GGATAGTGAAGCTGGGGGCTACTAA

Upstream 100 bases:

>100_bases
ATTAAACCAGTTCCTAAGTGACTGGCTGACGTTTTGTTTAAAAAATGGGATAAGCCAAGAACCCATTTTTTTAGAAAAGA
ATTAAAAGGTTGTAGCTATT

Downstream 100 bases:

>100_bases
TGAATAAACCAAGTTTGCTTTTGTATATCCACGGTTTTAACAGCTCTCCTTTATCTCATAAGGCACAAGTCATGGCTGAG
TATTGCAAAGTACACCGGCC

Product: cyclic 3',5'-adenosine monophosphate phosphodiesterase

Products: nucleoside 5'-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILATGDISQDHTVESYQHFVKGI
IPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQHWQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLV
LLHHHPLPAGSAWLDQHQLKESEQFWSVLAKHHNVNGIVCGHIHQELDRVVNGIRLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY

Sequences:

>Translated_274_residues
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILATGDISQDHTVESYQHFVKGI
IPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQHWQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLV
LLHHHPLPAGSAWLDQHQLKESEQFWSVLAKHHNVNGIVCGHIHQELDRVVNGIRLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY
>Mature_274_residues
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILATGDISQDHTVESYQHFVKGI
IPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQHWQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLV
LLHHHPLPAGSAWLDQHQLKESEQFWSVLAKHHNVNGIVCGHIHQELDRVVNGIRLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY

Specific function: Affects The Expression Of The Lacz Gene. [C]

COG id: COG1409

COG function: function code R; Predicted phosphohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli icc [H]

Homologues:

Organism=Escherichia coli, GI1789410, Length=261, Percent_Identity=53.639846743295, Blast_Score=271, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013622
- InterPro:   IPR004843
- ProDom:   PD587589 [H]

Pfam domain/function: PF00149 Metallophos; PF08413 Metallophos_C [H]

EC number: 3.1.4.17

Molecular weight: Translated: 30411; Mature: 30411

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILA
CCCCHHCCCCCCCEEEEEEECCEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEEE
TGDISQDHTVESYQHFVKGIIPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQH
ECCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
WQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLVLLHHHPLPAGSAWLDQHQLK
EEEEEECCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHH
ESEQFWSVLAKHHNVNGIVCGHIHQELDRVVNGIRLLATPSTCVQFLPDSDDFALDSQAP
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCEECCCCC
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY
CCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILA
CCCCHHCCCCCCCEEEEEEECCEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEEE
TGDISQDHTVESYQHFVKGIIPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQH
ECCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
WQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLVLLHHHPLPAGSAWLDQHQLK
EEEEEECCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHH
ESEQFWSVLAKHHNVNGIVCGHIHQELDRVVNGIRLLATPSTCVQFLPDSDDFALDSQAP
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCEECCCCC
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY
CCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nucleoside 3',5'-cyclic phosphate; H2O

Specific reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]