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The map label for this gene is ychM [H]

Identifier: 59712780

GI number: 59712780

Start: 2442124

End: 2443779

Strand: Reverse

Name: ychM [H]

Synonym: VF_2173

Alternate gene names: 59712780

Gene position: 2443779-2442124 (Counterclockwise)

Preceding gene: 59712782

Following gene: 59712779

Centisome position: 84.34

GC content: 40.64

Gene sequence:

>1656_bases
GTGTTTGGTCAACGGTTTGACAATATTAATTTAAAAGGGGACCTCTTTGGTGGGGTTACCACGGCCATAATATCGCTTCC
TCTCGCACTGGCGTTTGGTGTGGCATCTGGTGCTGGAGCTGAGGCCGGTCTTTGGGGGGCGATAATGGTGGGGCTTTTTG
CTTCATTATTTGGAGGCTCTTCAACGTTAATCTCTGAGCCAACAGGTCCCATGACCGTTATCATGACTGCTGTTTTAACT
AGCATGGTAGCGAAATATCCTGAAACGGGTATGGCAATGACGTTTACTGTTGTAATGATGGCCGGTGCGTTCCAAATTTT
ACTCGGTACATTAAAGCTTGGTAAATACATAACATTAATGCCTTATAGTGTAATTTCAGGTTTTATGTCTGGTATTGGTG
TCATTCTTATTATTCTTCAACTCTCTCCTTTATTAGGTCATGCGGCTCCACCGGGAGGCGTCATTGGAACCTTATCTGCT
TTACCTGATACTTTGTCTAATTTAGATATTAAAGAGTTGTTCCTTGGCGGGTTAACTCTTGGGGTGTTATTTTTATTTCC
TGATAAATATCGAAAATACGTGCCAGCTCAATTAGTGGCCCTTGTTGCGGTGACTCTGCTCTCTGTTCTTTTTTTTGATA
TGGAATCTATTCGCCGAATTGGTGAGATACCTGCTGGTCTACCTTCGCTTGTTATTCCAACCATTAATTTTGAAATGTTC
ACCACTATGGTTATTGACGCTTTGGTTCTTGGTACATTAGGTTGTATAGATACCTTATTGACTGCCGTGATTGGTGACTC
CTTAACACGTAAGGAGCACGATTCAGATAAAGAGCTACGAGGTCAAGGTTTAGCAAATATGATCTCTGGTTTATTTGGTG
CTTTACCTGGTGCAGGTGCCACTATGGGAACGGTAACCAATATTCAAGTTGGCGCTCGCTCACCGTTATCTGGTGTGTTT
AGGGCGGCAGTACTTGCTTTAGTCGTATTGGTTGCAGGTGGATTGACAGAACCTATTCCGATGGCGGTACTAGCAGGAAT
TGCAGTGTATGTCGGCTTTAATATCTTGGATTGGAGTTTTATTCAACGCGCACATAAAGTCAGTTTTGCTGGCATGGCTA
TTATGTATGGTGTGATGTTGCTGACTGTTTTTGTGGATTTAATTGTCGCTGTTGGTCTTGGTGTTTTTATTTCTAACATT
ATTATTATTGAGCGTTTAAGCCGAGAACAGGCAAGGCAAGTAAAAGCGATCAGTGATGCTGATGAAGATGATGTTCCTTT
AACTGACAGTGAAAGAGCTCTACTAGATAAAGCTAATGGTAAGGTGCTTTTCTTTTATTTATCAGGCCCAATGATATTCA
GTGTATCTAAAGCAATATCAAGGCAGCATAGCAGTATTTCTGATTATGAAGTGATGATACTTGATTTAACCGATGTTCCC
ATGATTGATGTGACCGTTGGTTTAGCGTTAGAGAATGCGATTAACGATGCACTAGATGCAAACTGTAAAGTATATTTACT
TTGTCCAAATGAGCAGACGAAAGAGCAATTAGATAAGTTTCATGTTACGGATTTAATTCCGAGTGAGAATACGTATAAAT
TTCGTTATGAGGCACTTAAGTCTGCAATTAAATATGTTTCACCTAGTGAAGATTAA

Upstream 100 bases:

>100_bases
AACATAAGTAGTAGTGATTAGTTCTAATTAACTATTATGAGAGATGAATAACATTTGTTAAATTAATGAGGTTAACGTGT
TTATAAACAAGGAGCTAACG

Downstream 100 bases:

>100_bases
GTGATTAATTATTATAGAAATAAATCAAACCGTAGAGTGAATTACTCTGCGGTTTTTTATTATCTATTAACGACACCAAT
TTGCATTCATCGCAATTTAA

Product: transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MFGQRFDNINLKGDLFGGVTTAIISLPLALAFGVASGAGAEAGLWGAIMVGLFASLFGGSSTLISEPTGPMTVIMTAVLT
SMVAKYPETGMAMTFTVVMMAGAFQILLGTLKLGKYITLMPYSVISGFMSGIGVILIILQLSPLLGHAAPPGGVIGTLSA
LPDTLSNLDIKELFLGGLTLGVLFLFPDKYRKYVPAQLVALVAVTLLSVLFFDMESIRRIGEIPAGLPSLVIPTINFEMF
TTMVIDALVLGTLGCIDTLLTAVIGDSLTRKEHDSDKELRGQGLANMISGLFGALPGAGATMGTVTNIQVGARSPLSGVF
RAAVLALVVLVAGGLTEPIPMAVLAGIAVYVGFNILDWSFIQRAHKVSFAGMAIMYGVMLLTVFVDLIVAVGLGVFISNI
IIIERLSREQARQVKAISDADEDDVPLTDSERALLDKANGKVLFFYLSGPMIFSVSKAISRQHSSISDYEVMILDLTDVP
MIDVTVGLALENAINDALDANCKVYLLCPNEQTKEQLDKFHVTDLIPSENTYKFRYEALKSAIKYVSPSED

Sequences:

>Translated_551_residues
MFGQRFDNINLKGDLFGGVTTAIISLPLALAFGVASGAGAEAGLWGAIMVGLFASLFGGSSTLISEPTGPMTVIMTAVLT
SMVAKYPETGMAMTFTVVMMAGAFQILLGTLKLGKYITLMPYSVISGFMSGIGVILIILQLSPLLGHAAPPGGVIGTLSA
LPDTLSNLDIKELFLGGLTLGVLFLFPDKYRKYVPAQLVALVAVTLLSVLFFDMESIRRIGEIPAGLPSLVIPTINFEMF
TTMVIDALVLGTLGCIDTLLTAVIGDSLTRKEHDSDKELRGQGLANMISGLFGALPGAGATMGTVTNIQVGARSPLSGVF
RAAVLALVVLVAGGLTEPIPMAVLAGIAVYVGFNILDWSFIQRAHKVSFAGMAIMYGVMLLTVFVDLIVAVGLGVFISNI
IIIERLSREQARQVKAISDADEDDVPLTDSERALLDKANGKVLFFYLSGPMIFSVSKAISRQHSSISDYEVMILDLTDVP
MIDVTVGLALENAINDALDANCKVYLLCPNEQTKEQLDKFHVTDLIPSENTYKFRYEALKSAIKYVSPSED
>Mature_551_residues
MFGQRFDNINLKGDLFGGVTTAIISLPLALAFGVASGAGAEAGLWGAIMVGLFASLFGGSSTLISEPTGPMTVIMTAVLT
SMVAKYPETGMAMTFTVVMMAGAFQILLGTLKLGKYITLMPYSVISGFMSGIGVILIILQLSPLLGHAAPPGGVIGTLSA
LPDTLSNLDIKELFLGGLTLGVLFLFPDKYRKYVPAQLVALVAVTLLSVLFFDMESIRRIGEIPAGLPSLVIPTINFEMF
TTMVIDALVLGTLGCIDTLLTAVIGDSLTRKEHDSDKELRGQGLANMISGLFGALPGAGATMGTVTNIQVGARSPLSGVF
RAAVLALVVLVAGGLTEPIPMAVLAGIAVYVGFNILDWSFIQRAHKVSFAGMAIMYGVMLLTVFVDLIVAVGLGVFISNI
IIIERLSREQARQVKAISDADEDDVPLTDSERALLDKANGKVLFFYLSGPMIFSVSKAISRQHSSISDYEVMILDLTDVP
MIDVTVGLALENAINDALDANCKVYLLCPNEQTKEQLDKFHVTDLIPSENTYKFRYEALKSAIKYVSPSED

Specific function: Possible Sulfate Transporter. [C]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI20336282, Length=545, Percent_Identity=22.3853211009174, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI16306483, Length=545, Percent_Identity=22.3853211009174, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI45827800, Length=496, Percent_Identity=22.7822580645161, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI39752683, Length=496, Percent_Identity=22.7822580645161, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI45827802, Length=446, Percent_Identity=22.8699551569507, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI94721259, Length=428, Percent_Identity=21.7289719626168, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI94721255, Length=428, Percent_Identity=21.7289719626168, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI94721253, Length=428, Percent_Identity=21.7289719626168, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI94721257, Length=428, Percent_Identity=21.7289719626168, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081859, Length=442, Percent_Identity=28.5067873303167, Blast_Score=157, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17566848, Length=540, Percent_Identity=24.6296296296296, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI86565215, Length=439, Percent_Identity=24.373576309795, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI86564196, Length=503, Percent_Identity=21.272365805169, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI86564876, Length=580, Percent_Identity=20.5172413793103, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17551690, Length=373, Percent_Identity=21.1796246648794, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319771, Length=449, Percent_Identity=22.271714922049, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323121, Length=412, Percent_Identity=21.6019417475728, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325260, Length=577, Percent_Identity=20.6239168110919, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358633, Length=426, Percent_Identity=23.0046948356808, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24666186, Length=411, Percent_Identity=21.4111922141119, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19922482, Length=524, Percent_Identity=21.9465648854962, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647160, Length=495, Percent_Identity=19.7979797979798, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355087, Length=495, Percent_Identity=19.7979797979798, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24651449, Length=394, Percent_Identity=21.5736040609137, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI85815873, Length=528, Percent_Identity=21.780303030303, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 58614; Mature: 58614

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCC
>Mature Secondary Structure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HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]