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The map label for this gene is surE

Identifier: 59712677

GI number: 59712677

Start: 2305920

End: 2306693

Strand: Reverse

Name: surE

Synonym: VF_2070

Alternate gene names: 59712677

Gene position: 2306693-2305920 (Counterclockwise)

Preceding gene: 59712678

Following gene: 59712676

Centisome position: 79.61

GC content: 40.57

Gene sequence:

>774_bases
ATGGAGACAAGAGTGAAGAAGTTACGCATTTTGCTTAGTAACGATGATGGTGTATTTGCTGAAGGGATAAATACGTTAGC
TCGTGTATTAGCTGATATTGCCGATATTACGATAGTAGCCCCTGATCGTAATCGTTCTGGTGCATCAAATTCTTTAACTC
TTGAATCCCCATTACGTGTTCGTCAAATTGATGAACACATTCATTCAGTGCAAGGGACACCAACCGATTGTGTTCACTTT
GCATTGAATGAATTAATGAAAGATAACTTGCCTGATTTGATTATTGCAGGTATCAATCATGGAGCAAATTTAGGTGATGA
TACCTTGTACTCAGGTACCGTCGCGGCTGCTACTGAAGGGCACTTTTTAGGTTTGCCTGCCATTGCAATCTCTCTGGTTG
GACGCGAGCATTTTGATACGGCAGCTCAAGTAGCATTAAAAATAGTTAAGAACCATTTAGTTTCCCCACTAACCACACAA
AAAGTATTAAATGTGAATGTGCCAGATTGTGAGTATGAGCAATTAATGGGCTGGGAAGTGACACGACTTGGTGCAAGGCA
TCATGCAGAGAGCATGATTAAAGATACTGATCCTCGTGGTGAGACCATCTATTGGTTAGGTCCTCCAGGCAAAAAACAAG
ATGCAGGTGAGGGAACGGACTTCTTTGTTGTAAAGCAGCACCGAGTATCAATAACACCATTACAAGTCGATTTAACGGCT
CATGATTCATTAGGTATGATTACTGATTGGTTATCATTAGAGAGTTCTAAATAA

Upstream 100 bases:

>100_bases
TTCTCATTAACTTCAGGCAGTTTTGCTACGGTAATCGTACGTGAATTGCTACAAGAAATTGAAGTTGAGCGTACTTATAG
CTCAAACGATTAATATTAAT

Downstream 100 bases:

>100_bases
TGCTTAATTCGCGTTCTGAATTACTAGATCAATTTTTGCGCCAACAAGGCATTAGAGACGAAGCTATTTTAGCGGCTATT
CGAGAATTACCAAGAGAGCG

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
METRVKKLRILLSNDDGVFAEGINTLARVLADIADITIVAPDRNRSGASNSLTLESPLRVRQIDEHIHSVQGTPTDCVHF
ALNELMKDNLPDLIIAGINHGANLGDDTLYSGTVAAATEGHFLGLPAIAISLVGREHFDTAAQVALKIVKNHLVSPLTTQ
KVLNVNVPDCEYEQLMGWEVTRLGARHHAESMIKDTDPRGETIYWLGPPGKKQDAGEGTDFFVVKQHRVSITPLQVDLTA
HDSLGMITDWLSLESSK

Sequences:

>Translated_257_residues
METRVKKLRILLSNDDGVFAEGINTLARVLADIADITIVAPDRNRSGASNSLTLESPLRVRQIDEHIHSVQGTPTDCVHF
ALNELMKDNLPDLIIAGINHGANLGDDTLYSGTVAAATEGHFLGLPAIAISLVGREHFDTAAQVALKIVKNHLVSPLTTQ
KVLNVNVPDCEYEQLMGWEVTRLGARHHAESMIKDTDPRGETIYWLGPPGKKQDAGEGTDFFVVKQHRVSITPLQVDLTA
HDSLGMITDWLSLESSK
>Mature_257_residues
METRVKKLRILLSNDDGVFAEGINTLARVLADIADITIVAPDRNRSGASNSLTLESPLRVRQIDEHIHSVQGTPTDCVHF
ALNELMKDNLPDLIIAGINHGANLGDDTLYSGTVAAATEGHFLGLPAIAISLVGREHFDTAAQVALKIVKNHLVSPLTTQ
KVLNVNVPDCEYEQLMGWEVTRLGARHHAESMIKDTDPRGETIYWLGPPGKKQDAGEGTDFFVVKQHRVSITPLQVDLTA
HDSLGMITDWLSLESSK

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=246, Percent_Identity=57.3170731707317, Blast_Score=284, Evalue=4e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_VIBF1 (Q5E331)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205453.1
- ProteinModelPortal:   Q5E331
- SMR:   Q5E331
- STRING:   Q5E331
- GeneID:   3279391
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_2070
- NMPDR:   fig|312309.3.peg.2068
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- PhylomeDB:   Q5E331
- ProtClustDB:   PRK00346
- BioCyc:   VFIS312309:VF2070-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28054; Mature: 28054

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRVKKLRILLSNDDGVFAEGINTLARVLADIADITIVAPDRNRSGASNSLTLESPLRV
CCCHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCEEECCCHHH
RQIDEHIHSVQGTPTDCVHFALNELMKDNLPDLIIAGINHGANLGDDTLYSGTVAAATEG
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEECCEEEECCCC
HFLGLPAIAISLVGREHFDTAAQVALKIVKNHLVSPLTTQKVLNVNVPDCEYEQLMGWEV
CEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCCCHHHHCCCHH
TRLGARHHAESMIKDTDPRGETIYWLGPPGKKQDAGEGTDFFVVKQHRVSITPLQVDLTA
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEEEEEEEEEC
HDSLGMITDWLSLESSK
CCCCCHHHHHHHCCCCC
>Mature Secondary Structure
METRVKKLRILLSNDDGVFAEGINTLARVLADIADITIVAPDRNRSGASNSLTLESPLRV
CCCHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCEEECCCHHH
RQIDEHIHSVQGTPTDCVHFALNELMKDNLPDLIIAGINHGANLGDDTLYSGTVAAATEG
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEECCEEEECCCC
HFLGLPAIAISLVGREHFDTAAQVALKIVKNHLVSPLTTQKVLNVNVPDCEYEQLMGWEV
CEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCCCHHHHCCCHH
TRLGARHHAESMIKDTDPRGETIYWLGPPGKKQDAGEGTDFFVVKQHRVSITPLQVDLTA
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEEEEEEEEEC
HDSLGMITDWLSLESSK
CCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA