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The map label for this gene is yeiM [C]

Identifier: 59712672

GI number: 59712672

Start: 2300968

End: 2302182

Strand: Reverse

Name: yeiM [C]

Synonym: VF_2065

Alternate gene names: 59712672

Gene position: 2302182-2300968 (Counterclockwise)

Preceding gene: 59712674

Following gene: 59712669

Centisome position: 79.45

GC content: 39.84

Gene sequence:

>1215_bases
ATGAATATTTTATTTAGCCTATTAGGCATGTGCGCACTGATTTTTTGTGCTTGGGTATTTTCAGAGAAGCGTTCAGCAAT
TAACTGGAAATTAGTATTTAAAGCCTTTTTATTACAACTCTCTTTTGCTGCTTTAGTATTGTATTTTCCTTTGGGGCAAA
AAGCGTTAGCGGGATTAAGTAGTGGTGTTTCTAGCTTACTTGGTTTTGCCGATGAAGGGATAGCATTCCTCTTTGGTGAT
CTTGCTTCTTCTGGTTTTATTTTTGCTATTCGCGTCCTTCCTATTATTATTTTCTTCAGTGCTCTAATCTCCGCTCTATA
TTATCTAGGTATTATGCAAAAAGTGATTTCTGTTCTTGGTGGCGGAATTCAAAAATTCTTAGGCACCAGCAAAGTAGAAT
CTCTCGTCGCAACAGGTAACATCTTCCTTTCTCAAGGTGAATCTCCTCTTCTTATTCGCCCATTCTTAGCTCAAATGACT
CGTTCTGAACTGTTCGCTGTAATGGCTGGTGGTATGGCATCGGTTGCTGGTAGCGTACTGGGTGGTTATGCCGGTTTAGG
TGTGGAACTTAAGTATCTGATTGCTGCAAGTTTTATGGCGGCTCCTGGTAGCTTATTAATGGCTAAGATTTTAATTCCTG
AGCAAGAAACCCCTGTTGACCAACATGATGTGACCATTGATAAAAGTGAGCAAAGCAACGTAATTGATGCTCTTGCAAGT
GGTGCAATGAATGGTATGAAGATTGCGGTTGCTGTAGGTACGATGTTGATTGCCTTTGTGAGTGTTATTGCAATGCTTAA
CAGCGGATTAGAAATGGTTGCTGAGTGGTTTGGTTTTGCTGGCATTACACTGCAAACCGTATTTGGTTACTTATTTGCTC
CAATCGCATGGGTTATTGGTATTCCAAAAGCTGAAATGGTAATGGCTGGTTCTTACATTGGCCAAAAAGTGGTTCTTAAT
GAATTCGTTGCATTTATCGACTTTGTTCAACATAAAGATCAGTTATCAGCATACAGCCAAGTAATTATTACTTTTGCACT
GTGTGGTTTTGCAAACATCAGTTCAATCGCTGTGCAATTAGGCTCTATTGGTGTGATGGCTCCAGAACGTCGTGCTGACG
TTGCAAACATGGGCTTTAAAGCAGTATTAGCGGGTACATTAGCTAACTTAATGAGTGCATGTTTAGCTGGTTTATTCTTT
AGCTTAGCAATGTAA

Upstream 100 bases:

>100_bases
TAACTTCCTCTTGGTGTAGTCATTCTTCACCGATCTCGTCATCTACGATGGCGGCTCCTTTTGTTTCTTCATTTTATTCT
AAAATCTCATAGGCATAATT

Downstream 100 bases:

>100_bases
AACATCGTTTATTGAAAATAAAAGCCCATGCAATGGTATTTGCATGGGCTTTTTTTGTATTGATTAGTGGAATTAACCAA
TCACAATTTGGCCTAAGACA

Product: nucleoside permease NupC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNILFSLLGMCALIFCAWVFSEKRSAINWKLVFKAFLLQLSFAALVLYFPLGQKALAGLSSGVSSLLGFADEGIAFLFGD
LASSGFIFAIRVLPIIIFFSALISALYYLGIMQKVISVLGGGIQKFLGTSKVESLVATGNIFLSQGESPLLIRPFLAQMT
RSELFAVMAGGMASVAGSVLGGYAGLGVELKYLIAASFMAAPGSLLMAKILIPEQETPVDQHDVTIDKSEQSNVIDALAS
GAMNGMKIAVAVGTMLIAFVSVIAMLNSGLEMVAEWFGFAGITLQTVFGYLFAPIAWVIGIPKAEMVMAGSYIGQKVVLN
EFVAFIDFVQHKDQLSAYSQVIITFALCGFANISSIAVQLGSIGVMAPERRADVANMGFKAVLAGTLANLMSACLAGLFF
SLAM

Sequences:

>Translated_404_residues
MNILFSLLGMCALIFCAWVFSEKRSAINWKLVFKAFLLQLSFAALVLYFPLGQKALAGLSSGVSSLLGFADEGIAFLFGD
LASSGFIFAIRVLPIIIFFSALISALYYLGIMQKVISVLGGGIQKFLGTSKVESLVATGNIFLSQGESPLLIRPFLAQMT
RSELFAVMAGGMASVAGSVLGGYAGLGVELKYLIAASFMAAPGSLLMAKILIPEQETPVDQHDVTIDKSEQSNVIDALAS
GAMNGMKIAVAVGTMLIAFVSVIAMLNSGLEMVAEWFGFAGITLQTVFGYLFAPIAWVIGIPKAEMVMAGSYIGQKVVLN
EFVAFIDFVQHKDQLSAYSQVIITFALCGFANISSIAVQLGSIGVMAPERRADVANMGFKAVLAGTLANLMSACLAGLFF
SLAM
>Mature_404_residues
MNILFSLLGMCALIFCAWVFSEKRSAINWKLVFKAFLLQLSFAALVLYFPLGQKALAGLSSGVSSLLGFADEGIAFLFGD
LASSGFIFAIRVLPIIIFFSALISALYYLGIMQKVISVLGGGIQKFLGTSKVESLVATGNIFLSQGESPLLIRPFLAQMT
RSELFAVMAGGMASVAGSVLGGYAGLGVELKYLIAASFMAAPGSLLMAKILIPEQETPVDQHDVTIDKSEQSNVIDALAS
GAMNGMKIAVAVGTMLIAFVSVIAMLNSGLEMVAEWFGFAGITLQTVFGYLFAPIAWVIGIPKAEMVMAGSYIGQKVVLN
EFVAFIDFVQHKDQLSAYSQVIITFALCGFANISSIAVQLGSIGVMAPERRADVANMGFKAVLAGTLANLMSACLAGLFF
SLAM

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI227116277, Length=414, Percent_Identity=35.7487922705314, Blast_Score=269, Evalue=3e-72,
Organism=Homo sapiens, GI42542381, Length=414, Percent_Identity=35.5072463768116, Blast_Score=258, Evalue=5e-69,
Organism=Homo sapiens, GI11545853, Length=415, Percent_Identity=36.144578313253, Blast_Score=254, Evalue=1e-67,
Organism=Escherichia coli, GI1788488, Length=416, Percent_Identity=44.2307692307692, Blast_Score=324, Evalue=5e-90,
Organism=Escherichia coli, GI1788485, Length=416, Percent_Identity=43.0288461538462, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI1788737, Length=398, Percent_Identity=30.6532663316583, Blast_Score=188, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17560276, Length=395, Percent_Identity=32.4050632911392, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI71991794, Length=397, Percent_Identity=32.2418136020151, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI25146537, Length=218, Percent_Identity=33.0275229357798, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45552517, Length=402, Percent_Identity=38.0597014925373, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI19921868, Length=402, Percent_Identity=38.0597014925373, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI45552519, Length=402, Percent_Identity=38.0597014925373, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI281360430, Length=395, Percent_Identity=36.7088607594937, Blast_Score=247, Evalue=8e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 42749; Mature: 42749

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILFSLLGMCALIFCAWVFSEKRSAINWKLVFKAFLLQLSFAALVLYFPLGQKALAGLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SGVSSLLGFADEGIAFLFGDLASSGFIFAIRVLPIIIFFSALISALYYLGIMQKVISVLG
HHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGIQKFLGTSKVESLVATGNIFLSQGESPLLIRPFLAQMTRSELFAVMAGGMASVAGSVL
CHHHHHHCHHHHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GGYAGLGVELKYLIAASFMAAPGSLLMAKILIPEQETPVDQHDVTIDKSEQSNVIDALAS
HHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHH
GAMNGMKIAVAVGTMLIAFVSVIAMLNSGLEMVAEWFGFAGITLQTVFGYLFAPIAWVIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
IPKAEMVMAGSYIGQKVVLNEFVAFIDFVQHKDQLSAYSQVIITFALCGFANISSIAVQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSIGVMAPERRADVANMGFKAVLAGTLANLMSACLAGLFFSLAM
HCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNILFSLLGMCALIFCAWVFSEKRSAINWKLVFKAFLLQLSFAALVLYFPLGQKALAGLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SGVSSLLGFADEGIAFLFGDLASSGFIFAIRVLPIIIFFSALISALYYLGIMQKVISVLG
HHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGIQKFLGTSKVESLVATGNIFLSQGESPLLIRPFLAQMTRSELFAVMAGGMASVAGSVL
CHHHHHHCHHHHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GGYAGLGVELKYLIAASFMAAPGSLLMAKILIPEQETPVDQHDVTIDKSEQSNVIDALAS
HHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHH
GAMNGMKIAVAVGTMLIAFVSVIAMLNSGLEMVAEWFGFAGITLQTVFGYLFAPIAWVIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
IPKAEMVMAGSYIGQKVVLNEFVAFIDFVQHKDQLSAYSQVIITFALCGFANISSIAVQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSIGVMAPERRADVANMGFKAVLAGTLANLMSACLAGLFFSLAM
HCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]