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The map label for this gene is estR [H]

Identifier: 59712581

GI number: 59712581

Start: 2207153

End: 2208052

Strand: Reverse

Name: estR [H]

Synonym: VF_1974

Alternate gene names: 59712581

Gene position: 2208052-2207153 (Counterclockwise)

Preceding gene: 59712584

Following gene: 59712580

Centisome position: 76.2

GC content: 39.89

Gene sequence:

>900_bases
ATGAATAAATGGCCCTCATTAAAACAGCTACACTACTTCATTACTCTGCACGAAACGCGTCATTTTGGTGAAGCTGCAGA
AAAATGTTTTGTTAGCCAATCAACCCTGAGTAAAGGGATACAAAACCTTGAAGAGTTGATCGGTTGTACATTATATGAAA
GAGATAAAAAAACACTTGTTTTTACCCCAGTAGGTGAAAGAGTCGTAGAGCAAGGACGAGAATTGTTGGCAAAAGGCCAA
GACCTGATTGAGCTAGGGTCTTTATGTCAAGGTGATTCAATGCAAGGTCAATTACGTGTTGGCTGCATACCGACTATTGC
GCCTTTTTTATTATGTGACTTAGTGCAAGAGGTGAATGAAAAATACCCTCAACTCACTCTATTACTAAGAGAAGATACGA
CGACGAATCTATTAGCGGCATTAAGACAAGGGCAATTAGATGTATTGATTCTTGCTCTTCCTGTTGATATTGCAGGAATG
GAAAGTCTGGTTGTTGGTCAAGACCCATTTAAAATGGTAATTAGTAAAGACCAAGCGAGTTCTATTTCTACGCCTATCCG
CTATGATGATTTGCCTGATGAGTTTGTGTTCTTACTAGAGAAAGAGCATTGCTTAACAGAACATGCTGTTTCAGCGTGTA
AGTTAACGAAGCGAGAAAAAATTAATCCATTCACCGCGACAAGCTTGCATACATTAGTACAGATGGTTGCCAATGGGTTG
GGTACTACTTTTATTCCTCAAATGGCGATTAAGCATGGATTACTCGATAATCAAAATTTAGTTGTCGTTGAGCCGCCAGG
CCAAGAAGCATCACGTGATATTGGTTTAGTATGGCGCCCAAGCTCTTCTCGTTTGCAGGCGTTTCATCAGTTAGCTGATA
TTGTCGAAGATATTTTATAG

Upstream 100 bases:

>100_bases
TTTGTTTTTTCATAACAAATGTTTCGACGGGACAAACTATAGTACAAAAGGTATGATTGAAAAAAGCGAATTAAATAGAT
TGATGTAATCGAGAAAAGCG

Downstream 100 bases:

>100_bases
TGAATTTCTTGATACAAGGCGATTATTTATTTTTATAAATAGTCGCCTTTCTACTTTTGAATAATGAAAGAAAATCGTGA
TCGCATTCTCACTTCTTTAT

Product: hydrogen peroxide-inducible genes activator, LysR family

Products: NA

Alternate protein names: Esterase operon transcriptional regulator [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNKWPSLKQLHYFITLHETRHFGEAAEKCFVSQSTLSKGIQNLEELIGCTLYERDKKTLVFTPVGERVVEQGRELLAKGQ
DLIELGSLCQGDSMQGQLRVGCIPTIAPFLLCDLVQEVNEKYPQLTLLLREDTTTNLLAALRQGQLDVLILALPVDIAGM
ESLVVGQDPFKMVISKDQASSISTPIRYDDLPDEFVFLLEKEHCLTEHAVSACKLTKREKINPFTATSLHTLVQMVANGL
GTTFIPQMAIKHGLLDNQNLVVVEPPGQEASRDIGLVWRPSSSRLQAFHQLADIVEDIL

Sequences:

>Translated_299_residues
MNKWPSLKQLHYFITLHETRHFGEAAEKCFVSQSTLSKGIQNLEELIGCTLYERDKKTLVFTPVGERVVEQGRELLAKGQ
DLIELGSLCQGDSMQGQLRVGCIPTIAPFLLCDLVQEVNEKYPQLTLLLREDTTTNLLAALRQGQLDVLILALPVDIAGM
ESLVVGQDPFKMVISKDQASSISTPIRYDDLPDEFVFLLEKEHCLTEHAVSACKLTKREKINPFTATSLHTLVQMVANGL
GTTFIPQMAIKHGLLDNQNLVVVEPPGQEASRDIGLVWRPSSSRLQAFHQLADIVEDIL
>Mature_299_residues
MNKWPSLKQLHYFITLHETRHFGEAAEKCFVSQSTLSKGIQNLEELIGCTLYERDKKTLVFTPVGERVVEQGRELLAKGQ
DLIELGSLCQGDSMQGQLRVGCIPTIAPFLLCDLVQEVNEKYPQLTLLLREDTTTNLLAALRQGQLDVLILALPVDIAGM
ESLVVGQDPFKMVISKDQASSISTPIRYDDLPDEFVFLLEKEHCLTEHAVSACKLTKREKINPFTATSLHTLVQMVANGL
GTTFIPQMAIKHGLLDNQNLVVVEPPGQEASRDIGLVWRPSSSRLQAFHQLADIVEDIL

Specific function: Transcriptional regulator of the esterase operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=295, Percent_Identity=35.2542372881356, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1787879, Length=282, Percent_Identity=28.7234042553192, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788748, Length=295, Percent_Identity=24.7457627118644, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI157672245, Length=263, Percent_Identity=24.3346007604563, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=24.0663900414938, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788887, Length=280, Percent_Identity=26.0714285714286, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790208, Length=268, Percent_Identity=25.7462686567164, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI145693105, Length=252, Percent_Identity=22.6190476190476, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787806, Length=292, Percent_Identity=21.5753424657534, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=26.5536723163842, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=22.2222222222222, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33303; Mature: 33303

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKWPSLKQLHYFITLHETRHFGEAAEKCFVSQSTLSKGIQNLEELIGCTLYERDKKTLV
CCCCCCHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCEEE
FTPVGERVVEQGRELLAKGQDLIELGSLCQGDSMQGQLRVGCIPTIAPFLLCDLVQEVNE
ECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
KYPQLTLLLREDTTTNLLAALRQGQLDVLILALPVDIAGMESLVVGQDPFKMVISKDQAS
CCCEEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHEECCCHHHHHEECCCHH
SISTPIRYDDLPDEFVFLLEKEHCLTEHAVSACKLTKREKINPFTATSLHTLVQMVANGL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
GTTFIPQMAIKHGLLDNQNLVVVEPPGQEASRDIGLVWRPSSSRLQAFHQLADIVEDIL
CHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNKWPSLKQLHYFITLHETRHFGEAAEKCFVSQSTLSKGIQNLEELIGCTLYERDKKTLV
CCCCCCHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCEEE
FTPVGERVVEQGRELLAKGQDLIELGSLCQGDSMQGQLRVGCIPTIAPFLLCDLVQEVNE
ECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
KYPQLTLLLREDTTTNLLAALRQGQLDVLILALPVDIAGMESLVVGQDPFKMVISKDQAS
CCCEEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHEECCCHHHHHEECCCHH
SISTPIRYDDLPDEFVFLLEKEHCLTEHAVSACKLTKREKINPFTATSLHTLVQMVANGL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
GTTFIPQMAIKHGLLDNQNLVVVEPPGQEASRDIGLVWRPSSSRLQAFHQLADIVEDIL
CHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA