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The map label for this gene is fabZ

Identifier: 59712558

GI number: 59712558

Start: 2180473

End: 2180925

Strand: Reverse

Name: fabZ

Synonym: VF_1951

Alternate gene names: 59712558

Gene position: 2180925-2180473 (Counterclockwise)

Preceding gene: 59712559

Following gene: 59712557

Centisome position: 75.27

GC content: 37.75

Gene sequence:

>453_bases
TTGACTCGTGAAAATAAAACATTAAATATTACTGAAATCCAAGAATTGCTACCTCATCGTTACCCATTTCTATTGGTTGA
CCGAGTAACTGATTTCGAAGAAGAGAAATACTTACACGCGATCAAGAATGTGTCTGTAAATGAACCTCAATTTACAGGTC
ACTTCCCACAAATGCCTATTTTCCCTGGTGTATTAATTCTTGAAGCAATGGCTCAAGCAACAGGTTTATTGGCTTTTAAA
TCATTCGGAGCTCCTGCTGAGAATGAACTGTACTACTTTGCAAGTATCGATAAAGCAAAATTCCGTAAACCAGTAGTACC
TGGTGATCAACTGGTTCTTGAAGTTGAATTTATTAAAGATCGTCGTGGTATCGCACTATTTAACGGTGTAGCAAAAGTAG
ATGGCGAAGTTGTATGTTCTGCTGAGCTTAAGTGTGCAAGACGAGAGTTTTAA

Upstream 100 bases:

>100_bases
AAGTATTGGTCTGCATTTTGCAGACCTTTTTCTATCTATTATTACTCTATTTGAGCTACACTATTGCTCAGATACGATAT
TGTTTTACAGGAATACTATT

Downstream 100 bases:

>100_bases
TTATGATTCATGAAACTGCTAAGATTCACCCATCAGCTGTTATTGAAGGTAACGTAACGATTGAAGCTAATGTATCTGTT
GGTCCATTTACTTACATTTC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTRENKTLNITEIQELLPHRYPFLLVDRVTDFEEEKYLHAIKNVSVNEPQFTGHFPQMPIFPGVLILEAMAQATGLLAFK
SFGAPAENELYYFASIDKAKFRKPVVPGDQLVLEVEFIKDRRGIALFNGVAKVDGEVVCSAELKCARREF

Sequences:

>Translated_150_residues
MTRENKTLNITEIQELLPHRYPFLLVDRVTDFEEEKYLHAIKNVSVNEPQFTGHFPQMPIFPGVLILEAMAQATGLLAFK
SFGAPAENELYYFASIDKAKFRKPVVPGDQLVLEVEFIKDRRGIALFNGVAKVDGEVVCSAELKCARREF
>Mature_149_residues
TRENKTLNITEIQELLPHRYPFLLVDRVTDFEEEKYLHAIKNVSVNEPQFTGHFPQMPIFPGVLILEAMAQATGLLAFKS
FGAPAENELYYFASIDKAKFRKPVVPGDQLVLEVEFIKDRRGIALFNGVAKVDGEVVCSAELKCARREF

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=147, Percent_Identity=68.7074829931973, Blast_Score=210, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_VIBF1 (Q5E3F0)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205334.1
- ProteinModelPortal:   Q5E3F0
- SMR:   Q5E3F0
- STRING:   Q5E3F0
- GeneID:   3278891
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_1951
- NMPDR:   fig|312309.3.peg.1951
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   Q5E3F0
- ProtClustDB:   PRK00006
- BioCyc:   VFIS312309:VF1951-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17033; Mature: 16902

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: ACT_SITE 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRENKTLNITEIQELLPHRYPFLLVDRVTDFEEEKYLHAIKNVSVNEPQFTGHFPQMPI
CCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
FPGVLILEAMAQATGLLAFKSFGAPAENELYYFASIDKAKFRKPVVPGDQLVLEVEFIKD
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHCCCCCCCCEEEEEEEEECC
RRGIALFNGVAKVDGEVVCSAELKCARREF
CCCEEEECCCHHCCCCEEEECHHHHHCCCC
>Mature Secondary Structure 
TRENKTLNITEIQELLPHRYPFLLVDRVTDFEEEKYLHAIKNVSVNEPQFTGHFPQMPI
CCCCCCCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
FPGVLILEAMAQATGLLAFKSFGAPAENELYYFASIDKAKFRKPVVPGDQLVLEVEFIKD
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHCCCCCCCCEEEEEEEEECC
RRGIALFNGVAKVDGEVVCSAELKCARREF
CCCEEEECCCHHCCCCEEEECHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA