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The map label for this gene is accA [H]

Identifier: 59712553

GI number: 59712553

Start: 2173344

End: 2174303

Strand: Reverse

Name: accA [H]

Synonym: VF_1946

Alternate gene names: 59712553

Gene position: 2174303-2173344 (Counterclockwise)

Preceding gene: 59712554

Following gene: 172087739

Centisome position: 75.04

GC content: 41.46

Gene sequence:

>960_bases
ATGAGCCTGAATTTTCTTGAATTTGAAAAACCAATTGCTGAACTAGAAGCGAAAGTAGAAGCGTTACGTGAGATCTCTCG
TCGTGGCGGTGAAAATGCGCTTGATCTAGAAAAAGAGATAAAGCAATTAGAAGATAAATGCCTTGAGCTTAAAAAGAAAA
CATTTAGTGATTTAGGTGCATGGGAAGTTGCTCAACTTGCTCGTCACCCAGAGCGTCCTTACGTTCTTGATTACATTGAG
CATATGTTTACTGAGTTTGATGAATTAGCAGGCGATCGTGCGTTTGCTGATGATAAAGCATTAGTTGGCGGTATTGCTCG
TTTAGATGGTCGCCCTGTAATGGTTATTGGTCATCAAAAAGGTCGTGGTACAAAAGAAAAAGTAATACGTAATTTTGGTA
TGCCAAAACCTGAAGGTTACCGTAAAGCGAAACGTTTAATGCAAATGGCTGAGCGTTTTAATATGCCAGTAATTACATTT
ATTGATACAGCAGGCGCTTACCCTGGTGTTGGTGCAGAAGAGCGCGGCCAATCAGAAGCTATCGCTATGAACCTAAAAAT
CATGTCTGAACTAAGTGTTCCAGTTATCTGTAACGTTGTTGGTGAAGGTGGTTCTGGTGGTGCATTAGCTATCGGTGTTG
GTGATTACGTAAACATGCTTCAATACTCAACGTATTCAGTAATTTCTCCAGAAGGTTGTGCTTCAATCTTATGGCGTGAT
TCAGATAAGGCGCCACAAGCTGCAGAAGCTATGGGTCTTGTTGCACCTCGCCTAAAAGAGCTTGAGCTGATTGATACGAT
TATTGATGAGCCTTTAGGTGGCGCACATCGTGATCATAAAGCGACAGCTGAGAACATTAAACAGCGTTTGCTTGAGCAGT
TAAAAGAGCTTGATGCATTTGATAATGAAGCTTTACTTGAGCGTCGTTACCAACGCTTAATGAGCTATGGTTACTGCTGA

Upstream 100 bases:

>100_bases
TTTAAAGTCGTTGCTTGGCGAACAACAAGTCGAGCTTGAATTTAACTAGATTATTGAAGAACACTAATTTGAGTGTTCTT
AAACTAACAAGGATTCTTTG

Downstream 100 bases:

>100_bases
TAGCATTTATTGATTCGCGCACAGTAGTCGCGTAATCCAATAAGATAGAGTAAAGTGAAAGCGAGCCTGAGTGCTCGCTT
TTTTATTGGAAGAAACCTTA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSLNFLEFEKPIAELEAKVEALREISRRGGENALDLEKEIKQLEDKCLELKKKTFSDLGAWEVAQLARHPERPYVLDYIE
HMFTEFDELAGDRAFADDKALVGGIARLDGRPVMVIGHQKGRGTKEKVIRNFGMPKPEGYRKAKRLMQMAERFNMPVITF
IDTAGAYPGVGAEERGQSEAIAMNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
SDKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRDHKATAENIKQRLLEQLKELDAFDNEALLERRYQRLMSYGYC

Sequences:

>Translated_319_residues
MSLNFLEFEKPIAELEAKVEALREISRRGGENALDLEKEIKQLEDKCLELKKKTFSDLGAWEVAQLARHPERPYVLDYIE
HMFTEFDELAGDRAFADDKALVGGIARLDGRPVMVIGHQKGRGTKEKVIRNFGMPKPEGYRKAKRLMQMAERFNMPVITF
IDTAGAYPGVGAEERGQSEAIAMNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
SDKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRDHKATAENIKQRLLEQLKELDAFDNEALLERRYQRLMSYGYC
>Mature_318_residues
SLNFLEFEKPIAELEAKVEALREISRRGGENALDLEKEIKQLEDKCLELKKKTFSDLGAWEVAQLARHPERPYVLDYIEH
MFTEFDELAGDRAFADDKALVGGIARLDGRPVMVIGHQKGRGTKEKVIRNFGMPKPEGYRKAKRLMQMAERFNMPVITFI
DTAGAYPGVGAEERGQSEAIAMNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDS
DKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRDHKATAENIKQRLLEQLKELDAFDNEALLERRYQRLMSYGYC

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=319, Percent_Identity=72.1003134796238, Blast_Score=488, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 35553; Mature: 35422

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNFLEFEKPIAELEAKVEALREISRRGGENALDLEKEIKQLEDKCLELKKKTFSDLGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
WEVAQLARHPERPYVLDYIEHMFTEFDELAGDRAFADDKALVGGIARLDGRPVMVIGHQK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRGTKEKVIRNFGMPKPEGYRKAKRLMQMAERFNMPVITFIDTAGAYPGVGAEERGQSEA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHCCCCHH
IAMNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
HHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRDHKATAENIKQRLLEQLKELDAF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DNEALLERRYQRLMSYGYC
CCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLNFLEFEKPIAELEAKVEALREISRRGGENALDLEKEIKQLEDKCLELKKKTFSDLGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
WEVAQLARHPERPYVLDYIEHMFTEFDELAGDRAFADDKALVGGIARLDGRPVMVIGHQK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRGTKEKVIRNFGMPKPEGYRKAKRLMQMAERFNMPVITFIDTAGAYPGVGAEERGQSEA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHCCCCHH
IAMNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
HHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRDHKATAENIKQRLLEQLKELDAF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DNEALLERRYQRLMSYGYC
CCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA