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The map label for this gene is pabC [H]

Identifier: 59712344

GI number: 59712344

Start: 1960920

End: 1961726

Strand: Reverse

Name: pabC [H]

Synonym: VF_1737

Alternate gene names: 59712344

Gene position: 1961726-1960920 (Counterclockwise)

Preceding gene: 59712345

Following gene: 59712343

Centisome position: 67.7

GC content: 36.43

Gene sequence:

>807_bases
ATGTTTTGGGTTAATGGAATGGAATCTGAATCACTTCCAATCAGTGATCGAGCAACTCAGTATGGTGATGGTTTTTTTAC
TACCATGAAGGTATTAAATAAGAAGATTTGTTTGTGGAAATTGCACTTAACTCGACTTAAAACCTCAGCAGAACGTTTAG
GTATAACGGAGCCAGATTGGTGTGTACTTGAAGAGCAAATGATTGGACTTGCTTCTAAAGTAATGAATGGTGGCATTAAA
ATCTTAATAACAAGAGGAAGTGGTGGGCGAGGTTACTCTCCTGAAGGATGTACAAACACGCAAGTGATTGTGTCGACTTT
TACACTGCCTGTCGAATATCAAGAATGGCAACAAAAAGGCATAGATTTAGGGATATCCGATATTCATCTAGGACTCAATC
CACTTTTAGCTGGAATGAAGCATCTAAACCGCCTAGAGCAAGTACTAATAAAGCAATCAGTGAAGAAAACAGATTACTTA
GATGTCATTGTTCTCGATATTAATAACAACATCGTTGAGACGTCGATAGGAAACATTTTTTGGGTTAAGGGTGATAGAAT
ATTTACCCCTAATTTATCATTAGCTGGTGTTGAAGGGGTGATGAAGACGCACATTAGTGAAATTGCTAAGAGTCATTATA
TCGACATAGAATCAGTACATTGTAATATTGATACGCTTGCAAATGCAGATGAAGTTTTTATCACTAACTCCTTATTTGAA
GTCGTACCGATAAATAAGATCAAAGAAATTCATTTTACCAAACATACATTAACTCATTGGTTTCAGGAGAAACTGTACTC
GTGTTGA

Upstream 100 bases:

>100_bases
GAAGCTTAACTAGTTTCCAAGAGTCAGTTACACTTTAAAGGCGGTTTGATATTATATCAAACCGCCTTTTTATTTATTAG
TCTGTTGGTTAGGAGTTGTC

Downstream 100 bases:

>100_bases
AAAAACTAATTATCATTATTTTATATCGTGTGATCGGGTCGATTGAGTCATTAGACTGATGCTAGAGAACGCTCAACTTG
TTGAAGTAAAACCAGGGACA

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MFWVNGMESESLPISDRATQYGDGFFTTMKVLNKKICLWKLHLTRLKTSAERLGITEPDWCVLEEQMIGLASKVMNGGIK
ILITRGSGGRGYSPEGCTNTQVIVSTFTLPVEYQEWQQKGIDLGISDIHLGLNPLLAGMKHLNRLEQVLIKQSVKKTDYL
DVIVLDINNNIVETSIGNIFWVKGDRIFTPNLSLAGVEGVMKTHISEIAKSHYIDIESVHCNIDTLANADEVFITNSLFE
VVPINKIKEIHFTKHTLTHWFQEKLYSC

Sequences:

>Translated_268_residues
MFWVNGMESESLPISDRATQYGDGFFTTMKVLNKKICLWKLHLTRLKTSAERLGITEPDWCVLEEQMIGLASKVMNGGIK
ILITRGSGGRGYSPEGCTNTQVIVSTFTLPVEYQEWQQKGIDLGISDIHLGLNPLLAGMKHLNRLEQVLIKQSVKKTDYL
DVIVLDINNNIVETSIGNIFWVKGDRIFTPNLSLAGVEGVMKTHISEIAKSHYIDIESVHCNIDTLANADEVFITNSLFE
VVPINKIKEIHFTKHTLTHWFQEKLYSC
>Mature_268_residues
MFWVNGMESESLPISDRATQYGDGFFTTMKVLNKKICLWKLHLTRLKTSAERLGITEPDWCVLEEQMIGLASKVMNGGIK
ILITRGSGGRGYSPEGCTNTQVIVSTFTLPVEYQEWQQKGIDLGISDIHLGLNPLLAGMKHLNRLEQVLIKQSVKKTDYL
DVIVLDINNNIVETSIGNIFWVKGDRIFTPNLSLAGVEGVMKTHISEIAKSHYIDIESVHCNIDTLANADEVFITNSLFE
VVPINKIKEIHFTKHTLTHWFQEKLYSC

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=262, Percent_Identity=41.2213740458015, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI48994963, Length=263, Percent_Identity=23.9543726235741, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30239; Mature: 30239

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWVNGMESESLPISDRATQYGDGFFTTMKVLNKKICLWKLHLTRLKTSAERLGITEPDW
CEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCH
CVLEEQMIGLASKVMNGGIKILITRGSGGRGYSPEGCTNTQVIVSTFTLPVEYQEWQQKG
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHCC
IDLGISDIHLGLNPLLAGMKHLNRLEQVLIKQSVKKTDYLDVIVLDINNNIVETSIGNIF
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCEE
WVKGDRIFTPNLSLAGVEGVMKTHISEIAKSHYIDIESVHCNIDTLANADEVFITNSLFE
EEECCEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHCCCCEEEEECCHHH
VVPINKIKEIHFTKHTLTHWFQEKLYSC
HCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFWVNGMESESLPISDRATQYGDGFFTTMKVLNKKICLWKLHLTRLKTSAERLGITEPDW
CEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCH
CVLEEQMIGLASKVMNGGIKILITRGSGGRGYSPEGCTNTQVIVSTFTLPVEYQEWQQKG
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHCC
IDLGISDIHLGLNPLLAGMKHLNRLEQVLIKQSVKKTDYLDVIVLDINNNIVETSIGNIF
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCEE
WVKGDRIFTPNLSLAGVEGVMKTHISEIAKSHYIDIESVHCNIDTLANADEVFITNSLFE
EEECCEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHCCCCEEEEECCHHH
VVPINKIKEIHFTKHTLTHWFQEKLYSC
HCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]