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The map label for this gene is ptsG [H]

Identifier: 59712339

GI number: 59712339

Start: 1955709

End: 1957136

Strand: Reverse

Name: ptsG [H]

Synonym: VF_1732

Alternate gene names: 59712339

Gene position: 1957136-1955709 (Counterclockwise)

Preceding gene: 59712340

Following gene: 172087724

Centisome position: 67.54

GC content: 43.63

Gene sequence:

>1428_bases
ATGTTTAAACACCTTTTTGCTAGCCTACAGAAAGTTGGTAAGGCGCTAATGCTGCCTGTATCAGTTCTTCCTGTTGCTGG
TATTCTTTTAGGGGTTGGTGCAGCCAACTTTAGTTTCCTTCCAGAAGTGGTTTCTCACTTAATGGAACAAGCTGGTGGTT
CAGTATTTGGTCAAATGGCTCTGCTATTTGCTGTTGGTACTGCACTTGGTTTTACAAACAATGATGGCGTTGCTGGTCTA
GCTGCTGTTGTTGGTTACGGCATCATGGTTGCTACATTAAAAGTAATGGCAACTGTAATGGGTGTTGATGGCATTGAGAC
TGGTGTTCTTGGTGGTATCCTAGCTGGTGGTGTTGCTGGTTGGGCATTCAACAAGTTCTACCGTATTCAACTTCCTGAAT
ACCTAGGTTTCTTCGCTGGTAAGCGTGCTGTGCCAATCGTAACTGGTTTTGCATCTATCGCTCTAGGTCTTATCCTATCA
GTTGTATGGCCTCCAATCGGTGGTGCTATTGCAGCATTCTCTGACTGGGCTGCACATCAAAACCCAGTAGCTGCATTCGG
TATCTACGGTGTTATTGAACGTTCTCTAATTCCTTTTGGTCTACACCATATCTGGAACGTACCGTTCTTCTACGAAGCTG
GTTCTTGTGTGAACAATGCTGGTGAACACGTAAATGGTATCATGACTTGTTTCCTAACTGCTGATGATGCATCTCGTGCA
GCAGGTAACGGTTTCGGTCAACTAGCTGGTGGTTACTTATTCAAAATGTTCGGTCTTCCTGCTGCTGCAATCGCAATTGC
ACACTCAGCAAAACCTGAAAACCGCGCTAAAGTAATGGGTATCATGGCATCTGCTGCGTTAACTTCATTCCTAACAGGTA
TTACTGAACCAATCGAATTCGCATTCCTATTCGTTGCTCCTGTACTGTACGCTATCCACGCTGTATTAGCTGGTGTTGCA
TACATGCTAACTAACGCACTAGGTATCGTTCACGGTCACACATTCTCAAATGGTTTCATTGACTTCGTTGTTCAATCTCC
ACGAGCTGAGAATATGCTTCTTCTTGTTGGTCTTGGTCTTGTTTACGCTGTTGTTTACTACGTAGTATTCCGCGCTGTAA
TCAAAGCAATGAACCTAAAAACACCTGGTCGTGAAGATGAAGATGACTCTGCTACTAAAGTAACAGGTTCTGAACTAGCT
GGTGAACTAGTTGCTGCATTCGGTGGTAAAGAGAACATCACTAACCTTGACGCTTGTATCACTCGTCTACGTGTTTCTGT
AGCGAATGTTGAAGCTGTAAACCAAGATAAACTAAAACAACTTGGCGCTGCTGGTGTTGTTGTAGCTGGTTCTGGTGTAC
AAGCTATCTTCGGTACTAAGTCTGATAACCTTAAAACAGACATGAATGAGTGGATTAGCAACAATTAA

Upstream 100 bases:

>100_bases
TTACAATTTATTGATTGCATCAAAGGCAAGGGGGATATTGCCGTAATTAATAAGTAAATAATTAAATCCAAATTGTAGTT
ATAAATATTAGGAGCAAAAC

Downstream 100 bases:

>100_bases
TTCATCATTGAAAGAATAAAAAAGGAGGCCAATTGGTCTCCTTTTTTTATTTTTGTTCTGGAAAGATAAATTCTTGGTGT
GAATCTAACCATGTAGGGTA

Product: PTS system glucose-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MFKHLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMALLFAVGTALGFTNNDGVAGL
AAVVGYGIMVATLKVMATVMGVDGIETGVLGGILAGGVAGWAFNKFYRIQLPEYLGFFAGKRAVPIVTGFASIALGLILS
VVWPPIGGAIAAFSDWAAHQNPVAAFGIYGVIERSLIPFGLHHIWNVPFFYEAGSCVNNAGEHVNGIMTCFLTADDASRA
AGNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEFAFLFVAPVLYAIHAVLAGVA
YMLTNALGIVHGHTFSNGFIDFVVQSPRAENMLLLVGLGLVYAVVYYVVFRAVIKAMNLKTPGREDEDDSATKVTGSELA
GELVAAFGGKENITNLDACITRLRVSVANVEAVNQDKLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISNN

Sequences:

>Translated_475_residues
MFKHLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMALLFAVGTALGFTNNDGVAGL
AAVVGYGIMVATLKVMATVMGVDGIETGVLGGILAGGVAGWAFNKFYRIQLPEYLGFFAGKRAVPIVTGFASIALGLILS
VVWPPIGGAIAAFSDWAAHQNPVAAFGIYGVIERSLIPFGLHHIWNVPFFYEAGSCVNNAGEHVNGIMTCFLTADDASRA
AGNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEFAFLFVAPVLYAIHAVLAGVA
YMLTNALGIVHGHTFSNGFIDFVVQSPRAENMLLLVGLGLVYAVVYYVVFRAVIKAMNLKTPGREDEDDSATKVTGSELA
GELVAAFGGKENITNLDACITRLRVSVANVEAVNQDKLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISNN
>Mature_475_residues
MFKHLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMALLFAVGTALGFTNNDGVAGL
AAVVGYGIMVATLKVMATVMGVDGIETGVLGGILAGGVAGWAFNKFYRIQLPEYLGFFAGKRAVPIVTGFASIALGLILS
VVWPPIGGAIAAFSDWAAHQNPVAAFGIYGVIERSLIPFGLHHIWNVPFFYEAGSCVNNAGEHVNGIMTCFLTADDASRA
AGNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEFAFLFVAPVLYAIHAVLAGVA
YMLTNALGIVHGHTFSNGFIDFVVQSPRAENMLLLVGLGLVYAVVYYVVFRAVIKAMNLKTPGREDEDDSATKVTGSELA
GELVAAFGGKENITNLDACITRLRVSVANVEAVNQDKLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISNN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=484, Percent_Identity=64.4628099173554, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI1786894, Length=479, Percent_Identity=39.0396659707724, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1787908, Length=517, Percent_Identity=33.8491295938104, Blast_Score=257, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 49570; Mature: 49570

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKHLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LLFAVGTALGFTNNDGVAGLAAVVGYGIMVATLKVMATVMGVDGIETGVLGGILAGGVAG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
WAFNKFYRIQLPEYLGFFAGKRAVPIVTGFASIALGLILSVVWPPIGGAIAAFSDWAAHQ
HHHHHEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
NPVAAFGIYGVIERSLIPFGLHHIWNVPFFYEAGSCVNNAGEHVNGIMTCFLTADDASRA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHEEEEEEEECCCHHHH
AGNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEF
CCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
AFLFVAPVLYAIHAVLAGVAYMLTNALGIVHGHTFSNGFIDFVVQSPRAENMLLLVGLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEHHHHHHH
VYAVVYYVVFRAVIKAMNLKTPGREDEDDSATKVTGSELAGELVAAFGGKENITNLDACI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEECHHHHHHHHHHHHCCCCCCCHHHHHH
TRLRVSVANVEAVNQDKLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISNN
HHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MFKHLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LLFAVGTALGFTNNDGVAGLAAVVGYGIMVATLKVMATVMGVDGIETGVLGGILAGGVAG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
WAFNKFYRIQLPEYLGFFAGKRAVPIVTGFASIALGLILSVVWPPIGGAIAAFSDWAAHQ
HHHHHEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
NPVAAFGIYGVIERSLIPFGLHHIWNVPFFYEAGSCVNNAGEHVNGIMTCFLTADDASRA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHEEEEEEEECCCHHHH
AGNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEF
CCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
AFLFVAPVLYAIHAVLAGVAYMLTNALGIVHGHTFSNGFIDFVVQSPRAENMLLLVGLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEHHHHHHH
VYAVVYYVVFRAVIKAMNLKTPGREDEDDSATKVTGSELAGELVAAFGGKENITNLDACI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEECHHHHHHHHHHHHCCCCCCCHHHHHH
TRLRVSVANVEAVNQDKLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISNN
HHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]