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The map label for this gene is aaeR [H]

Identifier: 59712297

GI number: 59712297

Start: 1902656

End: 1903531

Strand: Direct

Name: aaeR [H]

Synonym: VF_1690

Alternate gene names: 59712297

Gene position: 1902656-1903531 (Clockwise)

Preceding gene: 172087720

Following gene: 59712308

Centisome position: 65.66

GC content: 38.13

Gene sequence:

>876_bases
ATGAAATTAGATGATTTGAATTTGTTTCGACAAGTGGTTGAAAATGGCAGCTACACTGCAGCTTCAAGAAAAACCCTAAT
TCCTGTTGCGACAATTACTCGTCGGATTCAAGCTTTAGAAGATTCTTTAGATATTCGCTTACTCAACCGCCATGCCAGAA
AGTTATCTCTTACTGAAGCTGGCCAAAAGTTTTACGATGAATGCGCCCCTATTCTAGCAACGTTGGTAAATACCAGTGAA
TATCTAGGAGAAGAGTGTCGTGGTGCAGCTGGAAAACTTAAGATTGCCGCTCCTTCAAACTTAACTAAACGCATGATCCA
ACCAATTTTGAATAAGTTTATGCTGCTTTATCCAGACATTAGCATTAACTTAACCATGAGCAATCAACCTGAGCAACTTG
ATCCTACCGATTGGGACATTATTTTCCGTGTTGGTAAACAACGAGATTCATCTCTTATTGCTCGTCAAATTGGTTCTTTA
GAAGACATTTTAGTTGCTAGCCCGAGTTATCTAGAAAAAAACTCAGAGCCGACTCATGCGCAAGAATTGCATAAACACAG
TTTATTAAAAGGTAATCCTTTAATGCGTTGGCGCTTAACCAATAAAGATGGTGAATCCGTCACAATTACTGACGCTGGGC
GCTTTGAAGCAAGTGAACTTAACGTAATTCGCATGGCTTGTTCGAATGGATTGGGTATTACACTCATGCCAGATATTATG
ATCAGCCAATATCTAGAAGAAGGCTCACTTATTAGAGTATTAAGTGATTGGTCTGCAAACCCTCGTGATATTTATATGAT
CTATAATTACAAAGATCATCAACCAGAAAAAGTACGTTTATTTATCGATTTTGTAAGTAACCACATACCTGATTAA

Upstream 100 bases:

>100_bases
TTATTTATAGATTTTCATTTTAGTTGACTTATAACAACACCAACTCACGCATTTTTGTTACACTTTAGCGCTCTAAAAAA
CGGGAGAGTATCTTAATATA

Downstream 100 bases:

>100_bases
TTTACTCTCTACAAAAAAGCCTGTGAAATCACAGGCTTTTTTATTAAGCAAGAAATTAAATCTCTTCGTTATAAATATCT
AGACTTGCTACGTTTTGTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKLDDLNLFRQVVENGSYTAASRKTLIPVATITRRIQALEDSLDIRLLNRHARKLSLTEAGQKFYDECAPILATLVNTSE
YLGEECRGAAGKLKIAAPSNLTKRMIQPILNKFMLLYPDISINLTMSNQPEQLDPTDWDIIFRVGKQRDSSLIARQIGSL
EDILVASPSYLEKNSEPTHAQELHKHSLLKGNPLMRWRLTNKDGESVTITDAGRFEASELNVIRMACSNGLGITLMPDIM
ISQYLEEGSLIRVLSDWSANPRDIYMIYNYKDHQPEKVRLFIDFVSNHIPD

Sequences:

>Translated_291_residues
MKLDDLNLFRQVVENGSYTAASRKTLIPVATITRRIQALEDSLDIRLLNRHARKLSLTEAGQKFYDECAPILATLVNTSE
YLGEECRGAAGKLKIAAPSNLTKRMIQPILNKFMLLYPDISINLTMSNQPEQLDPTDWDIIFRVGKQRDSSLIARQIGSL
EDILVASPSYLEKNSEPTHAQELHKHSLLKGNPLMRWRLTNKDGESVTITDAGRFEASELNVIRMACSNGLGITLMPDIM
ISQYLEEGSLIRVLSDWSANPRDIYMIYNYKDHQPEKVRLFIDFVSNHIPD
>Mature_291_residues
MKLDDLNLFRQVVENGSYTAASRKTLIPVATITRRIQALEDSLDIRLLNRHARKLSLTEAGQKFYDECAPILATLVNTSE
YLGEECRGAAGKLKIAAPSNLTKRMIQPILNKFMLLYPDISINLTMSNQPEQLDPTDWDIIFRVGKQRDSSLIARQIGSL
EDILVASPSYLEKNSEPTHAQELHKHSLLKGNPLMRWRLTNKDGESVTITDAGRFEASELNVIRMACSNGLGITLMPDIM
ISQYLEEGSLIRVLSDWSANPRDIYMIYNYKDHQPEKVRLFIDFVSNHIPD

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=29.6551724137931, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=26.8965517241379, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=26.8965517241379, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=26.5734265734266, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=24.2320819112628, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=25.6944444444444, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=26.8041237113402, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789173, Length=285, Percent_Identity=22.8070175438596, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082132, Length=261, Percent_Identity=24.5210727969349, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788481, Length=297, Percent_Identity=23.2323232323232, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=21.9594594594595, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786448, Length=298, Percent_Identity=21.8120805369128, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32989; Mature: 32989

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDDLNLFRQVVENGSYTAASRKTLIPVATITRRIQALEDSLDIRLLNRHARKLSLTEA
CCCCHHHHHHHHHHCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQKFYDECAPILATLVNTSEYLGEECRGAAGKLKIAAPSNLTKRMIQPILNKFMLLYPDI
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHEEEECCC
SINLTMSNQPEQLDPTDWDIIFRVGKQRDSSLIARQIGSLEDILVASPSYLEKNSEPTHA
EEEEEECCCCCCCCCCCCEEHEEECCCCHHHHHHHHHCCHHHHHCCCCHHHHCCCCCCHH
QELHKHSLLKGNPLMRWRLTNKDGESVTITDAGRFEASELNVIRMACSNGLGITLMPDIM
HHHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHEEEEECCCCCCEEEEHHHH
ISQYLEEGSLIRVLSDWSANPRDIYMIYNYKDHQPEKVRLFIDFVSNHIPD
HHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEEEHEEHHHHCCCC
>Mature Secondary Structure
MKLDDLNLFRQVVENGSYTAASRKTLIPVATITRRIQALEDSLDIRLLNRHARKLSLTEA
CCCCHHHHHHHHHHCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQKFYDECAPILATLVNTSEYLGEECRGAAGKLKIAAPSNLTKRMIQPILNKFMLLYPDI
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHEEEECCC
SINLTMSNQPEQLDPTDWDIIFRVGKQRDSSLIARQIGSLEDILVASPSYLEKNSEPTHA
EEEEEECCCCCCCCCCCCEEHEEECCCCHHHHHHHHHCCHHHHHCCCCHHHHCCCCCCHH
QELHKHSLLKGNPLMRWRLTNKDGESVTITDAGRFEASELNVIRMACSNGLGITLMPDIM
HHHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHEEEEECCCCCCEEEEHHHH
ISQYLEEGSLIRVLSDWSANPRDIYMIYNYKDHQPEKVRLFIDFVSNHIPD
HHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEEEHEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]