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The map label for this gene is pgsA [H]

Identifier: 59712232

GI number: 59712232

Start: 1825722

End: 1826276

Strand: Reverse

Name: pgsA [H]

Synonym: VF_1625

Alternate gene names: 59712232

Gene position: 1826276-1825722 (Counterclockwise)

Preceding gene: 59712233

Following gene: 59712229

Centisome position: 63.03

GC content: 40.0

Gene sequence:

>555_bases
ATGCGATTAACAATACCAAATATACTCACGTTTATCCGACTAGCACTGATCCCTGTGTTTGTTGTTGTGTTCTACTTGCC
TTATGAATGGTCAGCTGTAGCTGCTGCAATGGTATTCTGGGTTGCAGGTTTTACTGATTGGTTAGATGGACTTTTAGCTC
GTAAACTGGGGCAAACTTCTCGCTTTGGTGCTTTTTTAGACCCAGTTGCTGATAAAGTCATGGTGGCTGCTGCTTTAATT
TTAATTACTGAGCATTATCATACAATTTGGATCACCATCCCTGCGATTACAATGATTGCACGTGAAATTATTATTTCTGC
ATTACGAGAGTGGATGGCTGAAATAGGAAAACGAGCAAGTGTTGCCGTATCTTGGGTTGGTAAAGTAAAAACTGTATCTC
AAATGTTTGCGCTTTGGGTTCTTATCTGGCGTTACGATGATTGGATGATCTGGTTAGGTTATGCCGCTCTATATATTGCA
ACTATTTTGACATATTGGTCGATGGTGCAGTACTTAGCTGCAGCAAAAGATGATCTACTTAATGCAGATGAATAG

Upstream 100 bases:

>100_bases
AGGCATTAGCCATTCTTTGGCAGAAAAAATACATGATGCGTTGAAACACGGATAAAAAAAGCGCACCATACACTCGCGGA
CCAAAACTTAAGAATTATTT

Downstream 100 bases:

>100_bases
ATATAAATGAATTGAAAAGCGAACTTAGGTTCGCTTTTTTTATATTTGAAATATTATTTTGCATAGTCAGCTGATATTAC
AGACTTTATCGTTTTGATTT

Product: phosphatidylglycerophosphate synthetase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MRLTIPNILTFIRLALIPVFVVVFYLPYEWSAVAAAMVFWVAGFTDWLDGLLARKLGQTSRFGAFLDPVADKVMVAAALI
LITEHYHTIWITIPAITMIAREIIISALREWMAEIGKRASVAVSWVGKVKTVSQMFALWVLIWRYDDWMIWLGYAALYIA
TILTYWSMVQYLAAAKDDLLNADE

Sequences:

>Translated_184_residues
MRLTIPNILTFIRLALIPVFVVVFYLPYEWSAVAAAMVFWVAGFTDWLDGLLARKLGQTSRFGAFLDPVADKVMVAAALI
LITEHYHTIWITIPAITMIAREIIISALREWMAEIGKRASVAVSWVGKVKTVSQMFALWVLIWRYDDWMIWLGYAALYIA
TILTYWSMVQYLAAAKDDLLNADE
>Mature_184_residues
MRLTIPNILTFIRLALIPVFVVVFYLPYEWSAVAAAMVFWVAGFTDWLDGLLARKLGQTSRFGAFLDPVADKVMVAAALI
LITEHYHTIWITIPAITMIAREIIISALREWMAEIGKRASVAVSWVGKVKTVSQMFALWVLIWRYDDWMIWLGYAALYIA
TILTYWSMVQYLAAAKDDLLNADE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=181, Percent_Identity=63.5359116022099, Blast_Score=237, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20981; Mature: 20981

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTIPNILTFIRLALIPVFVVVFYLPYEWSAVAAAMVFWVAGFTDWLDGLLARKLGQTS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RFGAFLDPVADKVMVAAALILITEHYHTIWITIPAITMIAREIIISALREWMAEIGKRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAVSWVGKVKTVSQMFALWVLIWRYDDWMIWLGYAALYIATILTYWSMVQYLAAAKDDLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NADE
CCCC
>Mature Secondary Structure
MRLTIPNILTFIRLALIPVFVVVFYLPYEWSAVAAAMVFWVAGFTDWLDGLLARKLGQTS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RFGAFLDPVADKVMVAAALILITEHYHTIWITIPAITMIAREIIISALREWMAEIGKRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAVSWVGKVKTVSQMFALWVLIWRYDDWMIWLGYAALYIATILTYWSMVQYLAAAKDDLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NADE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA