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The map label for this gene is grxC1 [H]

Identifier: 59712103

GI number: 59712103

Start: 1655358

End: 1655645

Strand: Reverse

Name: grxC1 [H]

Synonym: VF_1496

Alternate gene names: 59712103

Gene position: 1655645-1655358 (Counterclockwise)

Preceding gene: 59712104

Following gene: 59712102

Centisome position: 57.14

GC content: 32.64

Gene sequence:

>288_bases
ATGTTAAATACTCATCAAACGATCATTTTTTCAAAAACAGTATGTCCTTTTTGTGTTAAAGCAAAAGCAATTTTGGACGA
TAAAGGCATTGAATATAAAGTATTAACCTTAGATGAAGATCTAACAAAAGAAGAAATGGTTGCTTTAATTCAAGAAAAAG
AAAACATTACAGTGAATACCGTTCCTCAAATTTACCTTGACCGTAAATATATCGGTGGACATGACGATTTAGTGGCGTTT
TTTGAGCGTCAAGACACCGACATGGATTTAGGTGATTTTGAACTGTAG

Upstream 100 bases:

>100_bases
TGAACAACAGCTGCACCAGTTAATTCCTGAACTGCAAGCATACCCAGTTTTCAGCATTTAATTATCGAATTCGTATTATT
GAACTTAAAGAGAGCAAAAA

Downstream 100 bases:

>100_bases
AATACAGTAAATTAACATAGTTAACCTAAATGCTTTGGGTTTAATGATAAATAAGAGTGATAAATATGTGGAAATCTCTT
CTAACATTAGTGGAAGATGA

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MLNTHQTIIFSKTVCPFCVKAKAILDDKGIEYKVLTLDEDLTKEEMVALIQEKENITVNTVPQIYLDRKYIGGHDDLVAF
FERQDTDMDLGDFEL

Sequences:

>Translated_95_residues
MLNTHQTIIFSKTVCPFCVKAKAILDDKGIEYKVLTLDEDLTKEEMVALIQEKENITVNTVPQIYLDRKYIGGHDDLVAF
FERQDTDMDLGDFEL
>Mature_95_residues
MLNTHQTIIFSKTVCPFCVKAKAILDDKGIEYKVLTLDEDLTKEEMVALIQEKENITVNTVPQIYLDRKYIGGHDDLVAF
FERQDTDMDLGDFEL

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=80, Percent_Identity=40, Blast_Score=63, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 10943; Mature: 10943

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTHQTIIFSKTVCPFCVKAKAILDDKGIEYKVLTLDEDLTKEEMVALIQEKENITVNT
CCCCCCEEEEECCCCCHHHHHHEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEC
VPQIYLDRKYIGGHDDLVAFFERQDTDMDLGDFEL
CCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLNTHQTIIFSKTVCPFCVKAKAILDDKGIEYKVLTLDEDLTKEEMVALIQEKENITVNT
CCCCCCEEEEECCCCCHHHHHHEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEC
VPQIYLDRKYIGGHDDLVAFFERQDTDMDLGDFEL
CCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA