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The map label for this gene is rbsK [H]

Identifier: 59712055

GI number: 59712055

Start: 1598972

End: 1599889

Strand: Direct

Name: rbsK [H]

Synonym: VF_1448

Alternate gene names: 59712055

Gene position: 1598972-1599889 (Clockwise)

Preceding gene: 59712054

Following gene: 59712056

Centisome position: 55.18

GC content: 44.88

Gene sequence:

>918_bases
ATGAATAAATTAGTTGTTTTAGGTAGCGTAAACGCAGACCACGTTCTTCAAGTTGCTTCATTCCCTCGCCCTGGCGAGAC
GTTACACGGTCACAGCTATTCCGTTATTCCTGGTGGCAAAGGCGCAAACCAAGCGGTTGCGGCGGCACGTTTAGGTGCTG
ATATCGCATTTATCGCAAGTGTGGGTGATGACAGTTTTGGTCACCAGATGATTGAAGCTTTTCAGTTTGATGGCATTAAT
ACCGAAGCGGTGATGATTGAAGAAAATACACCAACCGGCATTGCGATGATCCAAGTAGCAGCGACCGGCGAAAACAGCAT
TTGTATTTCAGCAGAAGCAAATGCGCGTTTAACGGCAGATCGTATCGCTCCTCATCACGGATTAATCGAAGCCGCTGATA
CCCTATTAATGCAACTTGAAACGCCTATTGAAACCATAGAAAAAGCAGCACAAATTGCCAAAGCAGCAGGAACTAAAGTG
GTATTAAACCCAGCCCCTGCACATCAATTAAGTGATGACTTATTACAACTTGTTGATATCATTACACCAAACGAAACAGA
AGCCGAACTATTAACAGGCATTCAAGTAACGGATATGGCAAGCGCTCAACAAGCGGCTGATGCACTTCATGCAAAAGGCA
TCGAAACCGTAATGATCACCCTTGGCAGCAAAGGGGTCTGGATAAGCCAAAATGGTTCTGGTCGCCAAGTTGAAGGTTTC
AAAGTACAAGCGACAGATACAACAGGTGCAGGAGATACTTTCAACGGTGCATTCTTAACTGGATTACAATCAGGCCGTAA
ATTGGATGATGCTATCAAGTTTGCTCACGCTGCTGCCGCAATATCTGTAACTCGAATGGGTGCTCAAACGTCAATACCTT
CAATCACTGAAGTCGAACGTTTTCTCTTAGAGCATTGA

Upstream 100 bases:

>100_bases
ACCTATCGTTAAATGTACGAATTAATCAGTGAACTGATCGCCCATTTACCCATATGTTTTAAGACCACATTCCGGTCACA
GATAAGAAACAAGGCACATT

Downstream 100 bases:

>100_bases
TAATTAAATATCGTTGCCTGTATTTGTATTTAATGTAGGCAACGATATAAACAAGGATTGAATTTATGGCAACAATCAAA
GATGTAGCCAAACATGCAAG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADIAFIASVGDDSFGHQMIEAFQFDGIN
TEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTADRIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKV
VLNPAPAHQLSDDLLQLVDIITPNETEAELLTGIQVTDMASAQQAADALHAKGIETVMITLGSKGVWISQNGSGRQVEGF
KVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVERFLLEH

Sequences:

>Translated_305_residues
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADIAFIASVGDDSFGHQMIEAFQFDGIN
TEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTADRIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKV
VLNPAPAHQLSDDLLQLVDIITPNETEAELLTGIQVTDMASAQQAADALHAKGIETVMITLGSKGVWISQNGSGRQVEGF
KVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVERFLLEH
>Mature_305_residues
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADIAFIASVGDDSFGHQMIEAFQFDGIN
TEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTADRIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKV
VLNPAPAHQLSDDLLQLVDIITPNETEAELLTGIQVTDMASAQQAADALHAKGIETVMITLGSKGVWISQNGSGRQVEGF
KVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVERFLLEH

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=292, Percent_Identity=40.0684931506849, Blast_Score=177, Evalue=7e-45,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=56.5217391304348, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI87082343, Length=308, Percent_Identity=29.5454545454545, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87081971, Length=305, Percent_Identity=27.8688524590164, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788491, Length=254, Percent_Identity=24.4094488188976, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788484, Length=286, Percent_Identity=24.1258741258741, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87082281, Length=279, Percent_Identity=24.3727598566308, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=301, Percent_Identity=38.8704318936877, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=28.6144578313253, Blast_Score=115, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6322565, Length=290, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20128807, Length=305, Percent_Identity=38.3606557377049, Blast_Score=157, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24583886, Length=298, Percent_Identity=32.8859060402685, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31838; Mature: 31838

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADIAFIAS
CCCEEEEECCCHHHEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEE
VGDDSFGHQMIEAFQFDGINTEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTAD
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEEEECCCCEEEHH
RIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKVVLNPAPAHQLSDDLLQLVDI
HCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
ITPNETEAELLTGIQVTDMASAQQAADALHAKGIETVMITLGSKGVWISQNGSGRQVEGF
CCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCEECCE
KVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVER
EEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
FLLEH
HHHCC
>Mature Secondary Structure
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADIAFIAS
CCCEEEEECCCHHHEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEE
VGDDSFGHQMIEAFQFDGINTEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTAD
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEEEECCCCEEEHH
RIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKVVLNPAPAHQLSDDLLQLVDI
HCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
ITPNETEAELLTGIQVTDMASAQQAADALHAKGIETVMITLGSKGVWISQNGSGRQVEGF
CCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCEECCE
KVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVER
EEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
FLLEH
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]