Click here to switch to the map view.

The map label for this gene is higA-2 [H]

Identifier: 59711960

GI number: 59711960

Start: 1497166

End: 1497480

Strand: Reverse

Name: higA-2 [H]

Synonym: VF_1353

Alternate gene names: 59711960

Gene position: 1497480-1497166 (Counterclockwise)

Preceding gene: 59711961

Following gene: 172087699

Centisome position: 51.68

GC content: 43.49

Gene sequence:

>315_bases
ATGAGCAATCGTGACTTATTTACTGAATTAAGTTCAGCACTTGTTGAAGCTAAAGAGCATTCAGAGGGTAAAGTAACCCT
GAAAACTCACCAAGTTAATGACATCAGTGAGTTAGATATCTCGCCTGATGAAATTGTGAGTATTCGTGAGCAATTCAATA
TGTCTCGTGGTGTATTCGCTCGTTTACTGCATACATCATCACGTACATTAGAAAACTGGGAGCAGGGGCGCAGCGCACCT
AATGGGCAAGCTGTTACTCTTCTAAAGTTGGTTCAGCGCCACCCCGAAACTCTGTCGCACATCGCTGAACTATAG

Upstream 100 bases:

>100_bases
TTTGCTATCTGTACGTTACTTGCGTATACTTTGTATCTGGAAAGTATCGAAAGAATACCCCAGTGATAATGAGTTTAAGC
TTTTATGGAGGCGTGGCGCA

Downstream 100 bases:

>100_bases
CAATCTGTTTAAAAGTAATTCGCAACGCATGGCATTTTTACTATGCGTTGCATTTAGTTTTTAACGTGGCAGCGGCATCT
TTTCTCTCTACTTCAAACGA

Product: virulence gene repressor RsaL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MSNRDLFTELSSALVEAKEHSEGKVTLKTHQVNDISELDISPDEIVSIREQFNMSRGVFARLLHTSSRTLENWEQGRSAP
NGQAVTLLKLVQRHPETLSHIAEL

Sequences:

>Translated_104_residues
MSNRDLFTELSSALVEAKEHSEGKVTLKTHQVNDISELDISPDEIVSIREQFNMSRGVFARLLHTSSRTLENWEQGRSAP
NGQAVTLLKLVQRHPETLSHIAEL
>Mature_103_residues
SNRDLFTELSSALVEAKEHSEGKVTLKTHQVNDISELDISPDEIVSIREQFNMSRGVFARLLHTSSRTLENWEQGRSAPN
GQAVTLLKLVQRHPETLSHIAEL

Specific function: Antitoxin that counteracts the effect of the higB-2 toxin. Binds to its own promoter and regulates transcription of the higB-2/higA-2 operon [H]

COG id: COG2944

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 11721; Mature: 11590

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRDLFTELSSALVEAKEHSEGKVTLKTHQVNDISELDISPDEIVSIREQFNMSRGVFA
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHHHCCHHHHHH
RLLHTSSRTLENWEQGRSAPNGQAVTLLKLVQRHPETLSHIAEL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHCC
>Mature Secondary Structure 
SNRDLFTELSSALVEAKEHSEGKVTLKTHQVNDISELDISPDEIVSIREQFNMSRGVFA
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHHHCCHHHHHH
RLLHTSSRTLENWEQGRSAPNGQAVTLLKLVQRHPETLSHIAEL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]