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The map label for this gene is ccoN [H]

Identifier: 59711906

GI number: 59711906

Start: 1450804

End: 1452234

Strand: Direct

Name: ccoN [H]

Synonym: VF_1299

Alternate gene names: 59711906

Gene position: 1450804-1452234 (Clockwise)

Preceding gene: 59711901

Following gene: 59711907

Centisome position: 50.07

GC content: 40.88

Gene sequence:

>1431_bases
ATGAGCCAAGTACAGCAGCATGAACAAAACTACAACTATACCGTTGTTCGTCAGTTCTCTTTAGTTACCATACTTTGGGG
TATTGTTGGCATGGGTGTAGGTGTACTAATTGCCGCTCAGTTAGTTTGGCCGCAACTAAATTTCGACACACCATGGCTAA
CGTATAGCCGTTTGCGCCCTCTGCATACCAATGCAGTAATCTTCGCATTCGGTACAAGTGCCCTGTTCGCAACATCTTAT
TATGTTGTTCAGAGAACTTGTCAAACACGTTTGTTTGGTGGTCCATTAGTTGCGTTCACCTTCTGGGGATGGCAAGCAAT
TATTCTAGCAGCAGCAATTACGTTGCCTCTAGGTATTACATCAGGTAAAGAATATGCCGAATTAGAGTGGCCGATTGATA
TCGCTATTACACTAGTTTGGGTTGCGTATGCTATCGTATTCTTTGGAACCTTGTTTAAACGTAAAACATCTCATATTTAC
GTAGCTAACTGGTTTTTTGGAGCCTTCATTTTAACCGTTGCTGTTCTTCATATTGTGAATAGTCTTGCGGTTCCTGTATC
TCTAACAAAATCGTATTCAATGTACTCAGGTGCGGTCGATGCGATGGTTCAATGGTGGTACGGTCATAATGCGGTAGGTT
TCCTTTTAACTGCAGGTTTCTTAGGTATGATGTATTACTTCGTACCGAAACAAGCTGAACGTCCAGTTTACTCTTACCGT
TTATCTATTGTTCACTTCTGGGCATTAGTTTCTCTTTATATCTGGGCTGGTCCTCACCACTTACATTACACCGCACTACC
TGATTGGACACAGTCGCTTGGTATGGTGATGTCATTAGTCCTATTCGCACCATCATGGGGCGGCATGATTAATGGTATTA
TGACGTTATCTGGTGCTTGGCATAAGCTTCGTTATGACCCTATCTTACGTTTCCTAATTGTTTCTTTGTCCTTCTATGGT
ATGTCGACATTTGAAGGCCCAATGATGGCAATTAAATCTGTAAATGCCCTATCTCACTATACTGATTGGACAATTGGTCA
CGTACACTCTGGTGCTTTAGGTTGGGTTGCAATGGTTTCAATTGGTTCTTTATACCACTTAATTCCTAAGCTATTTGGTC
AAGAACGTATGTACTCTGTATCACTAATCAATGTTCACTTCTGGTTAGCAACAATCGGTACCGTTTTTTATATTGTAGCA
ATGTGGATTTCTGGTGTAATGCAAGGCTTGATGTGGCGAGCAGTAAATGCTGACGGTACATTAACATACAGCTTTGTTGA
ATCATTAGAAGCATCATACCCATTTTACTTCGTTCGCTTTATAGGTGGTTTAATCTTCTTATCAGGAATGTTCTTACTTG
CATACAATACATATAAGACCATTACTGCTCCGAAGAACAGCCTTAAAGCAATTCCACAACCGGCACAATAA

Upstream 100 bases:

>100_bases
TAATTATTTAGAAATAGAATTTTGGATGGCATTGCGGACATTATTGTTCGCACTAAGGAAAGTAAAGTGTAGTTAATAAT
AAAAGTGGAAGCATGCAATT

Downstream 100 bases:

>100_bases
GGAGACCATGTTATGAGTTCTAATCGTCATGAAATCATAGAAAAAAATGTTGGTCTTCTTGCGGTTCTTATCGTTGTTGC
TATCAGTTTTGGTGCATTAG

Product: cbb3-type cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome BB(3) subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSQVQQHEQNYNYTVVRQFSLVTILWGIVGMGVGVLIAAQLVWPQLNFDTPWLTYSRLRPLHTNAVIFAFGTSALFATSY
YVVQRTCQTRLFGGPLVAFTFWGWQAIILAAAITLPLGITSGKEYAELEWPIDIAITLVWVAYAIVFFGTLFKRKTSHIY
VANWFFGAFILTVAVLHIVNSLAVPVSLTKSYSMYSGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYSYR
LSIVHFWALVSLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAWHKLRYDPILRFLIVSLSFYG
MSTFEGPMMAIKSVNALSHYTDWTIGHVHSGALGWVAMVSIGSLYHLIPKLFGQERMYSVSLINVHFWLATIGTVFYIVA
MWISGVMQGLMWRAVNADGTLTYSFVESLEASYPFYFVRFIGGLIFLSGMFLLAYNTYKTITAPKNSLKAIPQPAQ

Sequences:

>Translated_476_residues
MSQVQQHEQNYNYTVVRQFSLVTILWGIVGMGVGVLIAAQLVWPQLNFDTPWLTYSRLRPLHTNAVIFAFGTSALFATSY
YVVQRTCQTRLFGGPLVAFTFWGWQAIILAAAITLPLGITSGKEYAELEWPIDIAITLVWVAYAIVFFGTLFKRKTSHIY
VANWFFGAFILTVAVLHIVNSLAVPVSLTKSYSMYSGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYSYR
LSIVHFWALVSLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAWHKLRYDPILRFLIVSLSFYG
MSTFEGPMMAIKSVNALSHYTDWTIGHVHSGALGWVAMVSIGSLYHLIPKLFGQERMYSVSLINVHFWLATIGTVFYIVA
MWISGVMQGLMWRAVNADGTLTYSFVESLEASYPFYFVRFIGGLIFLSGMFLLAYNTYKTITAPKNSLKAIPQPAQ
>Mature_475_residues
SQVQQHEQNYNYTVVRQFSLVTILWGIVGMGVGVLIAAQLVWPQLNFDTPWLTYSRLRPLHTNAVIFAFGTSALFATSYY
VVQRTCQTRLFGGPLVAFTFWGWQAIILAAAITLPLGITSGKEYAELEWPIDIAITLVWVAYAIVFFGTLFKRKTSHIYV
ANWFFGAFILTVAVLHIVNSLAVPVSLTKSYSMYSGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYSYRL
SIVHFWALVSLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAWHKLRYDPILRFLIVSLSFYGM
STFEGPMMAIKSVNALSHYTDWTIGHVHSGALGWVAMVSIGSLYHLIPKLFGQERMYSVSLINVHFWLATIGTVFYIVAM
WISGVMQGLMWRAVNADGTLTYSFVESLEASYPFYFVRFIGGLIFLSGMFLLAYNTYKTITAPKNSLKAIPQPAQ

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG3278

COG function: function code O; Cbb3-type cytochrome oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004677
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 53601; Mature: 53470

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCEEEECCCHHHHCCCCCCC
>Mature Secondary Structure 
SQVQQHEQNYNYTVVRQFSLVTILWGIVGMGVGVLIAAQLVWPQLNFDTPWLTYSRLRP
CCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCC
LHTNAVIFAFGTSALFATSYYVVQRTCQTRLFGGPLVAFTFWGWQAIILAAAITLPLGIT
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SGKEYAELEWPIDIAITLVWVAYAIVFFGTLFKRKTSHIYVANWFFGAFILTVAVLHIVN
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHH
SLAVPVSLTKSYSMYSGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYSYR
HHCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LSIVHFWALVSLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAW
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCH
HKLRYDPILRFLIVSLSFYGMSTFEGPMMAIKSVNALSHYTDWTIGHVHSGALGWVAMVS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHH
IGSLYHLIPKLFGQERMYSVSLINVHFWLATIGTVFYIVAMWISGVMQGLMWRAVNADGT
HHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
LTYSFVESLEASYPFYFVRFIGGLIFLSGMFLLAYNTYKTITAPKNSLKAIPQPAQ
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCEEEECCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7891558 [H]