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The map label for this gene is dcuD [H]

Identifier: 59711857

GI number: 59711857

Start: 1390529

End: 1391818

Strand: Direct

Name: dcuD [H]

Synonym: VF_1250

Alternate gene names: 59711857

Gene position: 1390529-1391818 (Clockwise)

Preceding gene: 59711856

Following gene: 59711858

Centisome position: 47.99

GC content: 29.46

Gene sequence:

>1290_bases
ATGCTTATGTCTATATTTATATTAACATTAATGATTTTATCTCTAATATATAAGAGAAAATACATACCTTTGATTTTTAT
ATTGTTAGGGATTGTTGTTTCCTTGTTTAATGGCGTAGAATTACGAGAAATCGCTTTAAACTTCTCTAATGCATTAAGCT
CTGTTTTTTTATCTATCGGGTTAAATATTGTTGTTATTATAGCGTTCTCTGAATATGTTAATAAAAATGGGGCAACAAAA
GATTTAGTTTTACTCGTTTATAAACCAATAAGTAAAATAAAAGATAGATACTTAATCCTTGCTATGTTTTATTTAATAGG
ATTAGCATTAAGCACAGTAATCACATCCGCATCAGCTCTATCTATGATATATATGTCTACTGTATTCCCTATACTGATAT
CTAAGGGAATAAGTAAAGAAGGTGCAGCGGGAATGATCGCTTCAGTTGGAGTAATAGAATTTGGTCACTTAAAATCGAGT
ACTATTTTTATGGCTGAAGAGCAAAATAGATTAATAAATGATTATGTTATTAATGGACAATTATTTTTATTTATTGGTAT
CGCTATTGTCGGTGCAATTAGCCATTACTTCTGGCAACGTTACCTCGATAACCGTTTGACTAATGATAACGATGAAAAAT
CATTAACAGATAATCTAGATTATCAGCATAAAATCAGTATATTTACGGCACTGCTACCGTTACTTCCGCTATTTCTTATT
TTACCTGAACATCTATTCACTAAACTAAACTTGCCACTTTGGACTATTGGGATGATATGTATTTCAATCTCGTTTATTTT
AGATCTAAAATCCAATAAATTTAATGTTAAAGAACAATTATCTTTCTTTTTAACTAGCATTAGTAACTCATTTTTCTTTA
TCGTATCTGTCATTGTTGGCGGTAAATTTCTAGTCAATTCGTTACCGATAGAAAGTATTATTAATATTTATAGCCATATG
TCTTTAGGTTCTATAAACCCGATTATTTTATCATCAGTATTATTATTGGCTATCGTGTTATTTTGTACTTTGCTTGGTTC
TGGAACGGTCTCTTTTATTACAATAACGTCAATAATGTCAAAATTTAAAATCGTATCGATGAATCAGTTCAGTTCAACAT
TTACATCGATGCAAATGATATCAGGAATAGGAAGAACAATATCCCCTGTATCTCCAACTACATTATTATGCTCCCAAATT
TCTGGAGTTACACTATCTAGCATAATATTAAGAAATATTGTCCCAACCATACTTATTGTAATTTTATCAATCATATACAG
CAATATTTGA

Upstream 100 bases:

>100_bases
ATACATCTGAGCAAATACTTAAAAATGGAAGAACATCTGAAATAGAATCTCACTTTCTATCAATAAAAAGAATGCTAGAT
CTCGTGCCTGGAACTCGGTA

Downstream 100 bases:

>100_bases
GGTTAGTTATGAATAAATACGTGATCATTCTGGAAGCTAGTGAAGATAAAAATAAGGATGATACTGGCTTTAGAAAAGAT
ACAGCACCGATAATTAAAGC

Product: C4-dicarboxylate anaerobic carrier

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLMSIFILTLMILSLIYKRKYIPLIFILLGIVVSLFNGVELREIALNFSNALSSVFLSIGLNIVVIIAFSEYVNKNGATK
DLVLLVYKPISKIKDRYLILAMFYLIGLALSTVITSASALSMIYMSTVFPILISKGISKEGAAGMIASVGVIEFGHLKSS
TIFMAEEQNRLINDYVINGQLFLFIGIAIVGAISHYFWQRYLDNRLTNDNDEKSLTDNLDYQHKISIFTALLPLLPLFLI
LPEHLFTKLNLPLWTIGMICISISFILDLKSNKFNVKEQLSFFLTSISNSFFFIVSVIVGGKFLVNSLPIESIINIYSHM
SLGSINPIILSSVLLLAIVLFCTLLGSGTVSFITITSIMSKFKIVSMNQFSSTFTSMQMISGIGRTISPVSPTTLLCSQI
SGVTLSSIILRNIVPTILIVILSIIYSNI

Sequences:

>Translated_429_residues
MLMSIFILTLMILSLIYKRKYIPLIFILLGIVVSLFNGVELREIALNFSNALSSVFLSIGLNIVVIIAFSEYVNKNGATK
DLVLLVYKPISKIKDRYLILAMFYLIGLALSTVITSASALSMIYMSTVFPILISKGISKEGAAGMIASVGVIEFGHLKSS
TIFMAEEQNRLINDYVINGQLFLFIGIAIVGAISHYFWQRYLDNRLTNDNDEKSLTDNLDYQHKISIFTALLPLLPLFLI
LPEHLFTKLNLPLWTIGMICISISFILDLKSNKFNVKEQLSFFLTSISNSFFFIVSVIVGGKFLVNSLPIESIINIYSHM
SLGSINPIILSSVLLLAIVLFCTLLGSGTVSFITITSIMSKFKIVSMNQFSSTFTSMQMISGIGRTISPVSPTTLLCSQI
SGVTLSSIILRNIVPTILIVILSIIYSNI
>Mature_429_residues
MLMSIFILTLMILSLIYKRKYIPLIFILLGIVVSLFNGVELREIALNFSNALSSVFLSIGLNIVVIIAFSEYVNKNGATK
DLVLLVYKPISKIKDRYLILAMFYLIGLALSTVITSASALSMIYMSTVFPILISKGISKEGAAGMIASVGVIEFGHLKSS
TIFMAEEQNRLINDYVINGQLFLFIGIAIVGAISHYFWQRYLDNRLTNDNDEKSLTDNLDYQHKISIFTALLPLLPLFLI
LPEHLFTKLNLPLWTIGMICISISFILDLKSNKFNVKEQLSFFLTSISNSFFFIVSVIVGGKFLVNSLPIESIINIYSHM
SLGSINPIILSSVLLLAIVLFCTLLGSGTVSFITITSIMSKFKIVSMNQFSSTFTSMQMISGIGRTISPVSPTTLLCSQI
SGVTLSSIILRNIVPTILIVILSIIYSNI

Specific function: May have a role in the transport of dicarboxylates from the periplasm across the inner membrane. Seems not to be essential for growth. It is likely to be a cryptic gene, as no or low expression has been found under a number of growth conditions and when t

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1789622, Length=375, Percent_Identity=26.9333333333333, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786839, Length=364, Percent_Identity=27.4725274725275, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 47475; Mature: 47475

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMSIFILTLMILSLIYKRKYIPLIFILLGIVVSLFNGVELREIALNFSNALSSVFLSIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
LNIVVIIAFSEYVNKNGATKDLVLLVYKPISKIKDRYLILAMFYLIGLALSTVITSASAL
CHHEEEEEEHHHHCCCCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMIYMSTVFPILISKGISKEGAAGMIASVGVIEFGHLKSSTIFMAEEQNRLINDYVINGQ
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCCCCEEEEECHHCCHHHHEEECCH
LFLFIGIAIVGAISHYFWQRYLDNRLTNDNDEKSLTDNLDYQHKISIFTALLPLLPLFLI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LPEHLFTKLNLPLWTIGMICISISFILDLKSNKFNVKEQLSFFLTSISNSFFFIVSVIVG
HHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHC
GKFLVNSLPIESIINIYSHMSLGSINPIILSSVLLLAIVLFCTLLGSGTVSFITITSIMS
CHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KFKIVSMNQFSSTFTSMQMISGIGRTISPVSPTTLLCSQISGVTLSSIILRNIVPTILIV
HHHEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ILSIIYSNI
HHHHHHHCC
>Mature Secondary Structure
MLMSIFILTLMILSLIYKRKYIPLIFILLGIVVSLFNGVELREIALNFSNALSSVFLSIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
LNIVVIIAFSEYVNKNGATKDLVLLVYKPISKIKDRYLILAMFYLIGLALSTVITSASAL
CHHEEEEEEHHHHCCCCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMIYMSTVFPILISKGISKEGAAGMIASVGVIEFGHLKSSTIFMAEEQNRLINDYVINGQ
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCCCCEEEEECHHCCHHHHEEECCH
LFLFIGIAIVGAISHYFWQRYLDNRLTNDNDEKSLTDNLDYQHKISIFTALLPLLPLFLI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LPEHLFTKLNLPLWTIGMICISISFILDLKSNKFNVKEQLSFFLTSISNSFFFIVSVIVG
HHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHC
GKFLVNSLPIESIINIYSHMSLGSINPIILSSVLLLAIVLFCTLLGSGTVSFITITSIMS
CHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KFKIVSMNQFSSTFTSMQMISGIGRTISPVSPTTLLCSQISGVTLSSIILRNIVPTILIV
HHHEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ILSIIYSNI
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]