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The map label for this gene is ubiG

Identifier: 59711810

GI number: 59711810

Start: 1338970

End: 1339674

Strand: Reverse

Name: ubiG

Synonym: VF_1203

Alternate gene names: 59711810

Gene position: 1339674-1338970 (Counterclockwise)

Preceding gene: 172087693

Following gene: 59711809

Centisome position: 46.23

GC content: 39.72

Gene sequence:

>705_bases
ATGACTCAGCAGTTAAATGTCGACCCGGCAGAAATCAAAAAATTTGAAGATATGGCTTCACGTTGGTGGGATTTAGAAGG
TGAATTTAAACCTCTACACCAAATTAATCCTCTTCGTTTAAATTACGTGCTTGAAAACGCGAATGGCCTCTTTGGTAAAA
AAGTACTTGATGTAGGCTGTGGTGGCGGGATTTTAGCTGAAAGCATGGCAAAACAAGGGGCAGATGTTATTGGTTTGGAT
ATGGGGAAAGAACCTTTAACTGTTGCACGCTTACACGCTTTAGAAACAGGAACCAAACTCGAATACGTTCAATCAACGGC
CGAACAACACGCTGAAGAGAACCCTGAGACGTATGATGTGGTTACCTGTATGGAAATGCTTGAGCACGTACCTGACCCAC
TTTCAGTTATCCGCTCTTGTGCAAAAATGGTAAAACCTGGCGGACACGTATTCTTCTCAACCCTGAACCGCAATATCAAG
TCTTATTTATTTGCTATTGTTGGTGCAGAGCAATTATTAAAATTAGTACCAAAAGGTACACACGATCATAATAAGTTCAT
TCGTCCTTCTGAACTGTTAAAAATGTTAGATCAAACTGCATTACAAGAACGTGGCATTACCGGTTTGCATTATAACCCTC
TTACCGATACCTACTCTCTTGGTAAGAATGTAGATGTTAATTATATTGTTCACACTACATTATAA

Upstream 100 bases:

>100_bases
TAAACCTCAGAAAATGTGCTGAAAAAATCGCCATTTTAAATACTCACTTTCTCATTTTTTTCTGTATATAATAGAGGGAT
ATAAAAAAGGAATATTAACT

Downstream 100 bases:

>100_bases
CCTTCTGCTTCTTTCTTAATCTAAATGGCTTTTTATTATACAAGCGTCTCATTAAAGAGCCATTTATAACCTTAATTAAT
ATACTGCTATACCTAAATTC

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTQQLNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLENANGLFGKKVLDVGCGGGILAESMAKQGADVIGLD
MGKEPLTVARLHALETGTKLEYVQSTAEQHAEENPETYDVVTCMEMLEHVPDPLSVIRSCAKMVKPGGHVFFSTLNRNIK
SYLFAIVGAEQLLKLVPKGTHDHNKFIRPSELLKMLDQTALQERGITGLHYNPLTDTYSLGKNVDVNYIVHTTL

Sequences:

>Translated_234_residues
MTQQLNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLENANGLFGKKVLDVGCGGGILAESMAKQGADVIGLD
MGKEPLTVARLHALETGTKLEYVQSTAEQHAEENPETYDVVTCMEMLEHVPDPLSVIRSCAKMVKPGGHVFFSTLNRNIK
SYLFAIVGAEQLLKLVPKGTHDHNKFIRPSELLKMLDQTALQERGITGLHYNPLTDTYSLGKNVDVNYIVHTTL
>Mature_233_residues
TQQLNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLENANGLFGKKVLDVGCGGGILAESMAKQGADVIGLDM
GKEPLTVARLHALETGTKLEYVQSTAEQHAEENPETYDVVTCMEMLEHVPDPLSVIRSCAKMVKPGGHVFFSTLNRNIKS
YLFAIVGAEQLLKLVPKGTHDHNKFIRPSELLKMLDQTALQERGITGLHYNPLTDTYSLGKNVDVNYIVHTTL

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=243, Percent_Identity=36.2139917695473, Blast_Score=179, Evalue=2e-45,
Organism=Escherichia coli, GI1788564, Length=227, Percent_Identity=71.8061674008811, Blast_Score=353, Evalue=8e-99,
Organism=Caenorhabditis elegans, GI115533050, Length=234, Percent_Identity=32.4786324786325, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324476, Length=232, Percent_Identity=32.7586206896552, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281365311, Length=236, Percent_Identity=33.0508474576271, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24585589, Length=228, Percent_Identity=32.8947368421053, Blast_Score=147, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_VIBF1 (Q5E5J8)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_204586.1
- ProteinModelPortal:   Q5E5J8
- STRING:   Q5E5J8
- GeneID:   3278569
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_1203
- NMPDR:   fig|312309.3.peg.1051
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   Q5E5J8
- ProtClustDB:   PRK05134
- BioCyc:   VFIS312309:VF1203-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 26116; Mature: 25985

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQLNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLENANGLFGKKVLDVGC
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHCCC
GGGILAESMAKQGADVIGLDMGKEPLTVARLHALETGTKLEYVQSTAEQHAEENPETYDV
CCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
VTCMEMLEHVPDPLSVIRSCAKMVKPGGHVFFSTLNRNIKSYLFAIVGAEQLLKLVPKGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HDHNKFIRPSELLKMLDQTALQERGITGLHYNPLTDTYSLGKNVDVNYIVHTTL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCEEEEEEECC
>Mature Secondary Structure 
TQQLNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLENANGLFGKKVLDVGC
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHCCC
GGGILAESMAKQGADVIGLDMGKEPLTVARLHALETGTKLEYVQSTAEQHAEENPETYDV
CCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
VTCMEMLEHVPDPLSVIRSCAKMVKPGGHVFFSTLNRNIKSYLFAIVGAEQLLKLVPKGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HDHNKFIRPSELLKMLDQTALQERGITGLHYNPLTDTYSLGKNVDVNYIVHTTL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA