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The map label for this gene is murQ [H]

Identifier: 59711721

GI number: 59711721

Start: 1226817

End: 1227719

Strand: Direct

Name: murQ [H]

Synonym: VF_1114

Alternate gene names: 59711721

Gene position: 1226817-1227719 (Clockwise)

Preceding gene: 59711718

Following gene: 59711722

Centisome position: 42.34

GC content: 40.97

Gene sequence:

>903_bases
ATGAAAATCGATTTAACAACATTAGTAACAGAGAGCCGTAACAAAGCGAGTGAAAATATCGATGTGTTATCAACGGTAGA
AATGCTAACCGTTATTAACCAAGAAGATCAAAAAGTTGCATTGGCTGTTGAAGCGATTCTTCCTCAAATTGCAGATGTTG
TTGATGCTATTGCCGTTGCTTTTCAATCTGGCGGTCGTTTGATTTACACAGGTGCGGGTACTTCAGGGCGTTTAGGTATT
TTGGATGCAAGTGAATGTCCTCCAACGTATGGTTCAAACCCTGATTTAGTTGTCGGCTTAATTGCTGGCGGACACAAAGC
GATTTTAAAAGCGGTTGAGAATGCTGAAGATAACCGTGAATTAGGCGCATCGGATCTACAAGACCTCGGTCTTAATGAGA
AAGATGTTTTAGTTGGTATTGCGGCAAGTGGTCGAACGCCTTATGTACTTGGTGCGATGGAATATGCGAAATCAGTAGGA
GCAACGGTTGCGACACTAAGTTGTAATCCAAATAGCCCAATGACAGAGCTTGCAGATATTAACATGACACCTGTTGTAGG
CCCTGAAGTAGTGACAGGTTCTTCTCGAATGAAGGCGGGAACAGCACAAAAATTAGTACTGAATATGCTAACAACAGGGG
CGATGATCCGCACTGGTAAAGTATTTGGAAATCTAATGGTTGACGTAGAAGCAACCAATGCAAAATTAGTTCAACGACAA
AAAAATATTGTGATTGAAGCAACAGGTTGCTCAGAAGTCGAAGCTTCAGAAGCATTATCTCAATGTGATAATCACTGTAA
AACAGCCATTTTAATGGTCTTGTCAGGGTTAGATGCACAAAGTGCGAAAGCAAAATTAGCACAACATAATGGCTTTATTC
GAAATGCACTTTCAGACCAGTAA

Upstream 100 bases:

>100_bases
GAATAACTTTTGTTGTGATTTTGGTCACTTTATGGAATTTTTTATTCTTTATGATAGCAAGCATCAAAATTAAGCATTTA
ACTTTTAAAGAGTACAGATT

Downstream 100 bases:

>100_bases
TTGGTAACAAGGCCTTATACCAATCTGGATGAATCAAATTTTATCTAGGTTGGTACCTCAACGAACAAATTAAAAAGGAA
CAGAAGATGGCTAAAATAAC

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKIDLTTLVTESRNKASENIDVLSTVEMLTVINQEDQKVALAVEAILPQIADVVDAIAVAFQSGGRLIYTGAGTSGRLGI
LDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRELGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMEYAKSVG
ATVATLSCNPNSPMTELADINMTPVVGPEVVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
KNIVIEATGCSEVEASEALSQCDNHCKTAILMVLSGLDAQSAKAKLAQHNGFIRNALSDQ

Sequences:

>Translated_300_residues
MKIDLTTLVTESRNKASENIDVLSTVEMLTVINQEDQKVALAVEAILPQIADVVDAIAVAFQSGGRLIYTGAGTSGRLGI
LDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRELGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMEYAKSVG
ATVATLSCNPNSPMTELADINMTPVVGPEVVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
KNIVIEATGCSEVEASEALSQCDNHCKTAILMVLSGLDAQSAKAKLAQHNGFIRNALSDQ
>Mature_300_residues
MKIDLTTLVTESRNKASENIDVLSTVEMLTVINQEDQKVALAVEAILPQIADVVDAIAVAFQSGGRLIYTGAGTSGRLGI
LDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRELGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMEYAKSVG
ATVATLSCNPNSPMTELADINMTPVVGPEVVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
KNIVIEATGCSEVEASEALSQCDNHCKTAILMVLSGLDAQSAKAKLAQHNGFIRNALSDQ

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=298, Percent_Identity=61.0738255033557, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31353; Mature: 31353

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDLTTLVTESRNKASENIDVLSTVEMLTVINQEDQKVALAVEAILPQIADVVDAIAVA
CEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FQSGGRLIYTGAGTSGRLGILDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRE
HHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCHH
LGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMEYAKSVGATVATLSCNPNSPMTELADI
CCCHHHHHCCCCCCCEEEEEECCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCHHHHHCC
NMTPVVGPEVVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
CCCCCCCCCEECCCCHHCCCHHHHHHHHHHHHCHHEEECCEEEEEEEEEECCCHHHHHHC
KNIVIEATGCSEVEASEALSQCDNHCKTAILMVLSGLDAQSAKAKLAQHNGFIRNALSDQ
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MKIDLTTLVTESRNKASENIDVLSTVEMLTVINQEDQKVALAVEAILPQIADVVDAIAVA
CEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FQSGGRLIYTGAGTSGRLGILDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRE
HHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCHH
LGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMEYAKSVGATVATLSCNPNSPMTELADI
CCCHHHHHCCCCCCCEEEEEECCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCHHHHHCC
NMTPVVGPEVVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
CCCCCCCCCEECCCCHHCCCHHHHHHHHHHHHCHHEEECCEEEEEEEEEECCCHHHHHHC
KNIVIEATGCSEVEASEALSQCDNHCKTAILMVLSGLDAQSAKAKLAQHNGFIRNALSDQ
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA