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The map label for this gene is yeiJ [C]

Identifier: 59711703

GI number: 59711703

Start: 1210685

End: 1211890

Strand: Direct

Name: yeiJ [C]

Synonym: VF_1096

Alternate gene names: 59711703

Gene position: 1210685-1211890 (Clockwise)

Preceding gene: 59711702

Following gene: 59711709

Centisome position: 41.78

GC content: 40.8

Gene sequence:

>1206_bases
ATGACATCTTTACTTGGTATTTTTGCCATTTTACTGTTTGCTTATTTGTGTTCGACTGACCGCCGTAACATCCCTCTTAG
AACTGTCTCTTTGGCGTTTGGACTACAAATTATTTTTGCCTTACTGGTTCTATATGTTCCTGCTGGTAAAGAGGTTTTAA
ACTCTGTTACAGCAGGCGTATCAGGCGTGATTGATTATGGTCAACAAGGTATTGCCTTTTTATTCGGCGGTTTAGCTACT
GGCAAAGTTGGCTTTGTATTTGCCATTAACGTGCTTGGTATTATCATTTTCTTCTCGGCACTCATTTCTGCGCTTTACCA
CATTGGTGTGATGCCTAAAGTGATTAATTTCATTGGTGGTGGATTACAACGTCTACTTGGTACAGGGCGTGCAGAATCCC
TTGCAGCAACGGCTAATATCTTTGTTAGTATGGTAGAAGCTCCATTAGTTGTTCGTCCTTACTTAAAGCACATGAGTGAT
TCTCAGTTTTTTGCTGTGATGACATGTGGCCTAGCTTCTGTAGCTGGCGGAACCATGGTTGGTTATGCATCATTAGGTGT
GGATCTAAACTTCCTTATCTCTGCTGCATTCATGTCTGCACCAGCAGGATTATTAATGGCTAAGATGATGGTTCCACCGG
GTGATGAAGCAAATAATGATGATGAAATTACCTCTGTTGAGATTGATCATGCAACTAATGTATTTGAAGCATTAGCTGAT
GGTGCTATGTCTGGCTTGCGTATCGCTGTTGCGGTAGGTACGACGTTATTAGCGTTTGTCAGTGTGATTGCTTTACTTAA
CGGCTTACTAGGGCATGTTGGTGATATCTTTGGTATCAAACTAAGTTTTGAATTAATTCTTGGTTACTTGTTTGCTCCTG
TAGCTTTCATCTTAGGTGTGCCATGGAATGAAGCGATTCTTGCTGGTTCATTAATCGGTAATAAGATCGTGGTAAATGAA
TTTGTTGCCTTTATTCAATTAATGGAAGTGAAAGATCAACTAAGTCCACATTCTGTTGCGATAGTTACATTCGCACTGTG
CGGCTTTGCAAATATTTCAACCATGGCAATTTTGATTGGTGGTTTAGGTAGTCTTGTTCCTGAACGTCGTCCATTTATTG
CGAGAATGGGGTTCAGAGCGATTACTGCAGGTGTATTGGCTAACTTAATGAGTGCAGCGATCGCTGGTGTGATTTTGTCA
CTTTAA

Upstream 100 bases:

>100_bases
TGACCTGTGTCTCATTAACAGAGTGGTAGCAAAGTCGACTTGCACGCAAACCTTTGCGGATTAGAATGCGAACTCATTTT
CGATAGCATAGGTTTCTATC

Downstream 100 bases:

>100_bases
GTTAATTGCTTAATTTCAAATAAAGAAAAGGTTGCGATCAAAAAGTCGCAACCTTTATTTTTTCTAGTCCCTAGTCCCTA
GTCCCTAGTCCCTAGTCCCT

Product: nucleoside permease NupC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTSLLGIFAILLFAYLCSTDRRNIPLRTVSLAFGLQIIFALLVLYVPAGKEVLNSVTAGVSGVIDYGQQGIAFLFGGLAT
GKVGFVFAINVLGIIIFFSALISALYHIGVMPKVINFIGGGLQRLLGTGRAESLAATANIFVSMVEAPLVVRPYLKHMSD
SQFFAVMTCGLASVAGGTMVGYASLGVDLNFLISAAFMSAPAGLLMAKMMVPPGDEANNDDEITSVEIDHATNVFEALAD
GAMSGLRIAVAVGTTLLAFVSVIALLNGLLGHVGDIFGIKLSFELILGYLFAPVAFILGVPWNEAILAGSLIGNKIVVNE
FVAFIQLMEVKDQLSPHSVAIVTFALCGFANISTMAILIGGLGSLVPERRPFIARMGFRAITAGVLANLMSAAIAGVILS
L

Sequences:

>Translated_401_residues
MTSLLGIFAILLFAYLCSTDRRNIPLRTVSLAFGLQIIFALLVLYVPAGKEVLNSVTAGVSGVIDYGQQGIAFLFGGLAT
GKVGFVFAINVLGIIIFFSALISALYHIGVMPKVINFIGGGLQRLLGTGRAESLAATANIFVSMVEAPLVVRPYLKHMSD
SQFFAVMTCGLASVAGGTMVGYASLGVDLNFLISAAFMSAPAGLLMAKMMVPPGDEANNDDEITSVEIDHATNVFEALAD
GAMSGLRIAVAVGTTLLAFVSVIALLNGLLGHVGDIFGIKLSFELILGYLFAPVAFILGVPWNEAILAGSLIGNKIVVNE
FVAFIQLMEVKDQLSPHSVAIVTFALCGFANISTMAILIGGLGSLVPERRPFIARMGFRAITAGVLANLMSAAIAGVILS
L
>Mature_400_residues
TSLLGIFAILLFAYLCSTDRRNIPLRTVSLAFGLQIIFALLVLYVPAGKEVLNSVTAGVSGVIDYGQQGIAFLFGGLATG
KVGFVFAINVLGIIIFFSALISALYHIGVMPKVINFIGGGLQRLLGTGRAESLAATANIFVSMVEAPLVVRPYLKHMSDS
QFFAVMTCGLASVAGGTMVGYASLGVDLNFLISAAFMSAPAGLLMAKMMVPPGDEANNDDEITSVEIDHATNVFEALADG
AMSGLRIAVAVGTTLLAFVSVIALLNGLLGHVGDIFGIKLSFELILGYLFAPVAFILGVPWNEAILAGSLIGNKIVVNEF
VAFIQLMEVKDQLSPHSVAIVTFALCGFANISTMAILIGGLGSLVPERRPFIARMGFRAITAGVLANLMSAAIAGVILSL

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI42542381, Length=409, Percent_Identity=36.4303178484108, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI227116277, Length=410, Percent_Identity=35.3658536585366, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI11545853, Length=358, Percent_Identity=36.8715083798883, Blast_Score=226, Evalue=4e-59,
Organism=Escherichia coli, GI1788485, Length=412, Percent_Identity=41.2621359223301, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1788488, Length=412, Percent_Identity=40.7766990291262, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1788737, Length=395, Percent_Identity=28.6075949367089, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17560276, Length=394, Percent_Identity=32.48730964467, Blast_Score=221, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI71991794, Length=412, Percent_Identity=32.7669902912621, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI25146537, Length=211, Percent_Identity=32.7014218009479, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45552517, Length=403, Percent_Identity=33.2506203473945, Blast_Score=227, Evalue=9e-60,
Organism=Drosophila melanogaster, GI19921868, Length=403, Percent_Identity=33.2506203473945, Blast_Score=227, Evalue=9e-60,
Organism=Drosophila melanogaster, GI45552519, Length=403, Percent_Identity=33.2506203473945, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI281360430, Length=400, Percent_Identity=33.25, Blast_Score=225, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 41913; Mature: 41782

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLLGIFAILLFAYLCSTDRRNIPLRTVSLAFGLQIIFALLVLYVPAGKEVLNSVTAGV
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SGVIDYGQQGIAFLFGGLATGKVGFVFAINVLGIIIFFSALISALYHIGVMPKVINFIGG
HHHHHCCCCHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GLQRLLGTGRAESLAATANIFVSMVEAPLVVRPYLKHMSDSQFFAVMTCGLASVAGGTMV
HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCE
GYASLGVDLNFLISAAFMSAPAGLLMAKMMVPPGDEANNDDEITSVEIDHATNVFEALAD
EHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
GAMSGLRIAVAVGTTLLAFVSVIALLNGLLGHVGDIFGIKLSFELILGYLFAPVAFILGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PWNEAILAGSLIGNKIVVNEFVAFIQLMEVKDQLSPHSVAIVTFALCGFANISTMAILIG
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLGSLVPERRPFIARMGFRAITAGVLANLMSAAIAGVILSL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSLLGIFAILLFAYLCSTDRRNIPLRTVSLAFGLQIIFALLVLYVPAGKEVLNSVTAGV
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SGVIDYGQQGIAFLFGGLATGKVGFVFAINVLGIIIFFSALISALYHIGVMPKVINFIGG
HHHHHCCCCHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GLQRLLGTGRAESLAATANIFVSMVEAPLVVRPYLKHMSDSQFFAVMTCGLASVAGGTMV
HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCE
GYASLGVDLNFLISAAFMSAPAGLLMAKMMVPPGDEANNDDEITSVEIDHATNVFEALAD
EHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
GAMSGLRIAVAVGTTLLAFVSVIALLNGLLGHVGDIFGIKLSFELILGYLFAPVAFILGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PWNEAILAGSLIGNKIVVNEFVAFIQLMEVKDQLSPHSVAIVTFALCGFANISTMAILIG
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLGSLVPERRPFIARMGFRAITAGVLANLMSAAIAGVILSL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]