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The map label for this gene is glnH [C]

Identifier: 59711700

GI number: 59711700

Start: 1207527

End: 1208627

Strand: Direct

Name: glnH [C]

Synonym: VF_1093

Alternate gene names: 59711700

Gene position: 1207527-1208627 (Clockwise)

Preceding gene: 59711697

Following gene: 59711701

Centisome position: 41.67

GC content: 35.69

Gene sequence:

>1101_bases
ATGCAGGGAGATAGGGTAAAGCGCTTGTGGTGTAAAGGAGTGATACGTTTATTCTCAATTCTATTGATTTTTAGTTCTTT
TTTTGTACAAGCACAGCCGCAATTAAAGGTGGGTGCTTATCATTGTCCTCCATTTATTTTTGAATCTAGCGAAGAGCAGT
ATGACGGTTTGAGTATGATTCTTTGGCAACGTATTGCTGAAATCATGCAAGTTGAATACAAGGTAAGTCATTATGGGCTT
CAAGAGTTACTTAGTGCGGCTGAAGTGGGTGAAATAGACGTAGGTGTTTCATGCATATCAATAACCCCTGACCGTGAAGA
ACATGTCGATTTTTCCCATTCCTTTTATGAAACTCACCTTGCCATAGCGGTTAAAAATCGAAGTTATCTTGATTCATTTA
TTAGCATTATTACTAATAAAACCTTATGGAAGGCTATTTGTCTCTTCTTATTTGTAGCGATCTCAGTAGGTACTTTTTAT
TACTTATTAGAGCGTAAAAATAACGATAAATTATATTCGATGCCAACCAAACGAGGACGCATAGCTGAAGCGTTTATTTT
AGGGGTGTTGTTTATTACTAAAGGGCCATTTAATTATTTTGAATTTAAAACATTGTCGGCAAGAGTGGTAACGGTATTAA
TTGCCATGTTTTCTACCGTATTTATCGCTAGTATCACAGCAGTACTAGCAAGTTCACTCACATTAGAGCAGTTAAGGTTT
GATGTAAAAGGCATCAATGATTTATCAAAAGTAAAAACGGGTGCGAAGCAAGGAACTACCGCTTCATTACTACTGAGTAA
TCACAGCATTGCCCACGATACCTACAAAGATATGGATGCGCTTTTATTGGCTCTTGAAAAAGGTCAATTAGATGCCGTTG
TCGCTGATGATGCTGTATTGCGATATATGATTAAGAAAGGAAAGGGAAAAGACTTATTTTTAGATTTAACGGTATTACCA
TATCAGTTAGAGAAGCAAAATTACGGTTTAGTATTAATTGAAAATAGTCCTTATGAAGAGAAAATTAATCGAGCACTATT
ACAAGTTCGAGAAACCAACGAATGGCATCAAATACTATTAGAGTATTTTGCTGAAAAATAA

Upstream 100 bases:

>100_bases
AAATCAATAACAAATATTCGAGATTATTTATAACCACTGCTACCTTTTAATATAGATATAAATAAAAAGAGTAAGCTCTA
TATTTTAAGGAGTTCATATT

Downstream 100 bases:

>100_bases
CAGAATTTGTGAGTAAAAAGTATCAGGTTTAGGTTGTGTCACGTATTATTGAAATTGCGACAATATAGAGTGAATTTAGG
AGTAATTGATGTCGAGTATG

Product: glutamate-gated potassium channel

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: Ionotropic Glutamate Receptor; Glutamate-Gated Potassium Channel; Ligand-Gated Ion Channel Family Protein; Ion Transport 2 Domain-Containing Protein; Ion Channel Family; Ligand-Gated Ion Channel Periplasmic Domain

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MQGDRVKRLWCKGVIRLFSILLIFSSFFVQAQPQLKVGAYHCPPFIFESSEEQYDGLSMILWQRIAEIMQVEYKVSHYGL
QELLSAAEVGEIDVGVSCISITPDREEHVDFSHSFYETHLAIAVKNRSYLDSFISIITNKTLWKAICLFLFVAISVGTFY
YLLERKNNDKLYSMPTKRGRIAEAFILGVLFITKGPFNYFEFKTLSARVVTVLIAMFSTVFIASITAVLASSLTLEQLRF
DVKGINDLSKVKTGAKQGTTASLLLSNHSIAHDTYKDMDALLLALEKGQLDAVVADDAVLRYMIKKGKGKDLFLDLTVLP
YQLEKQNYGLVLIENSPYEEKINRALLQVRETNEWHQILLEYFAEK

Sequences:

>Translated_366_residues
MQGDRVKRLWCKGVIRLFSILLIFSSFFVQAQPQLKVGAYHCPPFIFESSEEQYDGLSMILWQRIAEIMQVEYKVSHYGL
QELLSAAEVGEIDVGVSCISITPDREEHVDFSHSFYETHLAIAVKNRSYLDSFISIITNKTLWKAICLFLFVAISVGTFY
YLLERKNNDKLYSMPTKRGRIAEAFILGVLFITKGPFNYFEFKTLSARVVTVLIAMFSTVFIASITAVLASSLTLEQLRF
DVKGINDLSKVKTGAKQGTTASLLLSNHSIAHDTYKDMDALLLALEKGQLDAVVADDAVLRYMIKKGKGKDLFLDLTVLP
YQLEKQNYGLVLIENSPYEEKINRALLQVRETNEWHQILLEYFAEK
>Mature_366_residues
MQGDRVKRLWCKGVIRLFSILLIFSSFFVQAQPQLKVGAYHCPPFIFESSEEQYDGLSMILWQRIAEIMQVEYKVSHYGL
QELLSAAEVGEIDVGVSCISITPDREEHVDFSHSFYETHLAIAVKNRSYLDSFISIITNKTLWKAICLFLFVAISVGTFY
YLLERKNNDKLYSMPTKRGRIAEAFILGVLFITKGPFNYFEFKTLSARVVTVLIAMFSTVFIASITAVLASSLTLEQLRF
DVKGINDLSKVKTGAKQGTTASLLLSNHSIAHDTYKDMDALLLALEKGQLDAVVADDAVLRYMIKKGKGKDLFLDLTVLP
YQLEKQNYGLVLIENSPYEEKINRALLQVRETNEWHQILLEYFAEK

Specific function: Involved In A Glutamine-Transport System Glnhpq. [C]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI197313638, Length=284, Percent_Identity=26.4084507042254, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI197313636, Length=284, Percent_Identity=26.4084507042254, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4504125, Length=284, Percent_Identity=26.4084507042254, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI55770854, Length=297, Percent_Identity=26.5993265993266, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI153946391, Length=294, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147803, Length=367, Percent_Identity=22.0708446866485, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24648559, Length=361, Percent_Identity=23.5457063711911, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24644257, Length=292, Percent_Identity=24.6575342465753, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: 1440 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 460 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41650; Mature: 41650

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGDRVKRLWCKGVIRLFSILLIFSSFFVQAQPQLKVGAYHCPPFIFESSEEQYDGLSMI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCEECCCCEECCCCCHHCHHHHH
LWQRIAEIMQVEYKVSHYGLQELLSAAEVGEIDVGVSCISITPDREEHVDFSHSFYETHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEECCCCHHHCCHHHHHHHEEE
AIAVKNRSYLDSFISIITNKTLWKAICLFLFVAISVGTFYYLLERKNNDKLYSMPTKRGR
EEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCH
IAEAFILGVLFITKGPFNYFEFKTLSARVVTVLIAMFSTVFIASITAVLASSLTLEQLRF
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKGINDLSKVKTGAKQGTTASLLLSNHSIAHDTYKDMDALLLALEKGQLDAVVADDAVL
HHCCCCHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
RYMIKKGKGKDLFLDLTVLPYQLEKQNYGLVLIENSPYEEKINRALLQVRETNEWHQILL
HHHHHCCCCCEEEEEEEECCEEECCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
EYFAEK
HHHHCC
>Mature Secondary Structure
MQGDRVKRLWCKGVIRLFSILLIFSSFFVQAQPQLKVGAYHCPPFIFESSEEQYDGLSMI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCEECCCCEECCCCCHHCHHHHH
LWQRIAEIMQVEYKVSHYGLQELLSAAEVGEIDVGVSCISITPDREEHVDFSHSFYETHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEECCCCHHHCCHHHHHHHEEE
AIAVKNRSYLDSFISIITNKTLWKAICLFLFVAISVGTFYYLLERKNNDKLYSMPTKRGR
EEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCH
IAEAFILGVLFITKGPFNYFEFKTLSARVVTVLIAMFSTVFIASITAVLASSLTLEQLRF
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKGINDLSKVKTGAKQGTTASLLLSNHSIAHDTYKDMDALLLALEKGQLDAVVADDAVL
HHCCCCHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
RYMIKKGKGKDLFLDLTVLPYQLEKQNYGLVLIENSPYEEKINRALLQVRETNEWHQILL
HHHHHCCCCCEEEEEEEECCEEECCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
EYFAEK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: Translocates substrate across the membrane [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA