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The map label for this gene is dcuB [H]

Identifier: 59711695

GI number: 59711695

Start: 1198671

End: 1199984

Strand: Direct

Name: dcuB [H]

Synonym: VF_1088

Alternate gene names: 59711695

Gene position: 1198671-1199984 (Clockwise)

Preceding gene: 59711694

Following gene: 59711696

Centisome position: 41.37

GC content: 39.04

Gene sequence:

>1314_bases
ATGTTTTTAATTGAGTTTTTAATCGTACTAGTATGTATTTTAATCGGTGCTCGAATTGGTGGTATCGGTTTAGGTGTTAT
GGGTGGTATTGGTTTAGCCATACTAAGTTTTGTTTTTGGTTTACAACCGACAAGTCCGCCTATTGATGTAATGTTGATGA
TCATGGCTGTAGTAGCTGCTGCTGCTGCAATGCAAGCTGCTGGTGGTCTTGAATATTTAATCAAAATTGCTTCAAATATT
CTTCGTAAAAATCCTCGTCATATTACTTTTATTGCCCCTTTAGTGACGTACATGTTTACTTTCTTGGCAGGTACTGGACA
CGTAGCTTATTCAGTTTTACCTGTTATTGCAGAAGTAAGCCGTCGTAGTGGTATTCGCCCAGAACGTCCACTTGGAATGG
CAGTAATTGCTTCTCAATTTGCAATTGTAGCGAGTCCAATTGCTGCTGCGGTTGTCGCTGTTGTTGCCTTTTTAGAGCCA
CAAGGAATTACTTTAGCTGATGTATTAATGGTAACGATTCCGGGCACATTCTGTGGTTTAGCACTAGCTTGCGTTATTGT
TAACAAGATTGGTAAAGAGCTAAAAGACGATCCTGAATACCAACGTCGTATGCAAGATCCAACGTTCCGTAAGGAAATGG
AACAAGAAGTACAAGTAGAAGAAATTGAAATTAAACCAGAAGCTAAAAAAGCGGTAGGACTATTCCTATTTGGTGCATTC
GCCGTGGTTATTATGGGTGCATTCCCTGCATTACGTCCTAACTTCAATGGATCTCCAATGGGCATGGCTCATACTATTGA
AATCGTAATGTTAGCAATGGCAGCTTTAATTATTTTACTATGTAAGCCTGATGGAAATGAAATAACACAAGGTTCAGTTT
TCCATGCAGGTATGCGTGCAATCGTAGCTATATTTGGTATTGCATGGTTAGGTGATACGTTTATCGCAGGTCATGACATC
ATGGTAAAAGAAGCGGTATCTGGCTTAGTTGAAGTTGCTCCATGGACATTTGCTTTTGCATTGTTTGGTTTATCTGTAAT
GGTAAACAGTCAAGGCGCAACAACGGCAGTATTAGTACCTGTAGGTATTGCATTAGGCTTACCACCAGAAGTGATTATCG
CAACATTTGTTGCTGTAAATGGTTACTTCTTTATTCCTAACTATGGTCCGATTATCGCATCTATTGATTTTGACCGTACA
GGCACAACTAAGATTGGTAAATACATTTTTAACCACAGCTTTATGCTTCCTGGTCTATTAAGTATGATCTTCAGTATCGT
GTTCGGATTTATTTTTGCAAGCATGGTTTTATAA

Upstream 100 bases:

>100_bases
ACCCGATTATTATTCGCTCGATTTTGGAGTTTAAATTGCAGACGAATAACGTAGCAATTTAAAAATTTATTATATAAAAG
CTATCATCAGGGAGATTGAT

Downstream 100 bases:

>100_bases
CGCTTAATCAAAAATATAAATACACTTTAATTAGAACAAAGGCGAGCCTTAATGGCTCGCCTTTTTTTGTTTGATTTCTC
AAATGTGAAAAGATTAACAT

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MFLIEFLIVLVCILIGARIGGIGLGVMGGIGLAILSFVFGLQPTSPPIDVMLMIMAVVAAAAAMQAAGGLEYLIKIASNI
LRKNPRHITFIAPLVTYMFTFLAGTGHVAYSVLPVIAEVSRRSGIRPERPLGMAVIASQFAIVASPIAAAVVAVVAFLEP
QGITLADVLMVTIPGTFCGLALACVIVNKIGKELKDDPEYQRRMQDPTFRKEMEQEVQVEEIEIKPEAKKAVGLFLFGAF
AVVIMGAFPALRPNFNGSPMGMAHTIEIVMLAMAALIILLCKPDGNEITQGSVFHAGMRAIVAIFGIAWLGDTFIAGHDI
MVKEAVSGLVEVAPWTFAFALFGLSVMVNSQGATTAVLVPVGIALGLPPEVIIATFVAVNGYFFIPNYGPIIASIDFDRT
GTTKIGKYIFNHSFMLPGLLSMIFSIVFGFIFASMVL

Sequences:

>Translated_437_residues
MFLIEFLIVLVCILIGARIGGIGLGVMGGIGLAILSFVFGLQPTSPPIDVMLMIMAVVAAAAAMQAAGGLEYLIKIASNI
LRKNPRHITFIAPLVTYMFTFLAGTGHVAYSVLPVIAEVSRRSGIRPERPLGMAVIASQFAIVASPIAAAVVAVVAFLEP
QGITLADVLMVTIPGTFCGLALACVIVNKIGKELKDDPEYQRRMQDPTFRKEMEQEVQVEEIEIKPEAKKAVGLFLFGAF
AVVIMGAFPALRPNFNGSPMGMAHTIEIVMLAMAALIILLCKPDGNEITQGSVFHAGMRAIVAIFGIAWLGDTFIAGHDI
MVKEAVSGLVEVAPWTFAFALFGLSVMVNSQGATTAVLVPVGIALGLPPEVIIATFVAVNGYFFIPNYGPIIASIDFDRT
GTTKIGKYIFNHSFMLPGLLSMIFSIVFGFIFASMVL
>Mature_437_residues
MFLIEFLIVLVCILIGARIGGIGLGVMGGIGLAILSFVFGLQPTSPPIDVMLMIMAVVAAAAAMQAAGGLEYLIKIASNI
LRKNPRHITFIAPLVTYMFTFLAGTGHVAYSVLPVIAEVSRRSGIRPERPLGMAVIASQFAIVASPIAAAVVAVVAFLEP
QGITLADVLMVTIPGTFCGLALACVIVNKIGKELKDDPEYQRRMQDPTFRKEMEQEVQVEEIEIKPEAKKAVGLFLFGAF
AVVIMGAFPALRPNFNGSPMGMAHTIEIVMLAMAALIILLCKPDGNEITQGSVFHAGMRAIVAIFGIAWLGDTFIAGHDI
MVKEAVSGLVEVAPWTFAFALFGLSVMVNSQGATTAVLVPVGIALGLPPEVIIATFVAVNGYFFIPNYGPIIASIDFDRT
GTTKIGKYIFNHSFMLPGLLSMIFSIVFGFIFASMVL

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=439, Percent_Identity=41.002277904328, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI1790565, Length=405, Percent_Identity=41.7283950617284, Blast_Score=309, Evalue=3e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 46543; Mature: 46543

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLIEFLIVLVCILIGARIGGIGLGVMGGIGLAILSFVFGLQPTSPPIDVMLMIMAVVAA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AAAMQAAGGLEYLIKIASNILRKNPRHITFIAPLVTYMFTFLAGTGHVAYSVLPVIAEVS
HHHHHHHCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RRSGIRPERPLGMAVIASQFAIVASPIAAAVVAVVAFLEPQGITLADVLMVTIPGTFCGL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
ALACVIVNKIGKELKDDPEYQRRMQDPTFRKEMEQEVQVEEIEIKPEAKKAVGLFLFGAF
HHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHH
AVVIMGAFPALRPNFNGSPMGMAHTIEIVMLAMAALIILLCKPDGNEITQGSVFHAGMRA
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
IVAIFGIAWLGDTFIAGHDIMVKEAVSGLVEVAPWTFAFALFGLSVMVNSQGATTAVLVP
HHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEH
VGIALGLPPEVIIATFVAVNGYFFIPNYGPIIASIDFDRTGTTKIGKYIFNHSFMLPGLL
HHHHHCCCHHHHHHHHHHHCCEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHH
SMIFSIVFGFIFASMVL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFLIEFLIVLVCILIGARIGGIGLGVMGGIGLAILSFVFGLQPTSPPIDVMLMIMAVVAA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AAAMQAAGGLEYLIKIASNILRKNPRHITFIAPLVTYMFTFLAGTGHVAYSVLPVIAEVS
HHHHHHHCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RRSGIRPERPLGMAVIASQFAIVASPIAAAVVAVVAFLEPQGITLADVLMVTIPGTFCGL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
ALACVIVNKIGKELKDDPEYQRRMQDPTFRKEMEQEVQVEEIEIKPEAKKAVGLFLFGAF
HHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHH
AVVIMGAFPALRPNFNGSPMGMAHTIEIVMLAMAALIILLCKPDGNEITQGSVFHAGMRA
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
IVAIFGIAWLGDTFIAGHDIMVKEAVSGLVEVAPWTFAFALFGLSVMVNSQGATTAVLVP
HHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEH
VGIALGLPPEVIIATFVAVNGYFFIPNYGPIIASIDFDRTGTTKIGKYIFNHSFMLPGLL
HHHHHCCCHHHHHHHHHHHCCEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHH
SMIFSIVFGFIFASMVL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]