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The map label for this gene is pkn1 [H]

Identifier: 59711684

GI number: 59711684

Start: 1189415

End: 1190173

Strand: Reverse

Name: pkn1 [H]

Synonym: VF_1077

Alternate gene names: 59711684

Gene position: 1190173-1189415 (Counterclockwise)

Preceding gene: 59711685

Following gene: 59711683

Centisome position: 41.08

GC content: 38.47

Gene sequence:

>759_bases
ATGAGTATAATGAATAATATGGTACTAATTTCAGGTCAACCTTACCAAAGAGGGTCGATTCTAAGTTCTGATGAGCAACC
AATAAAAACCATCTCACTCTCTCCATTCTTTATGGATATACACCCAGTATTAAATAAAGATTACCGTGTTTTTATTGAGC
AAGGTGGTTATTCAGACCCTAGATATTGGTCAACAACTGGATTCAAATTCATCCAAGAGCACAATATTACTGAACCTTTA
TATTGGAATGATCCCAATTGGAATGGGGATAAAAAACCAGTCACAGGGATCAGTTGGTATGAAGCTCAAGCTTTTGCTTG
TTTTGTTGGTAAAGAACTTCCAACTGAATCGCAGTGGGAATACGCGGCAAAAGGAAATGATAACCGTATGTATCCTTGGG
GAAATACAGAGCCAGATTTAAATATCGCGAATTTCGCTCCCGATTGTGAACCAGTTGAATTTAATCGAAGCTCAACAGAC
TGGGATGCTCATCCACAAAATCGATCTCCTTTTGGTTGTATAGACATGGGGGGAAACCTTGCAGAGTGGTGTTTAGATAA
TTATTTACCGAATTATGCATGGGATGATAACCATGTTGATCCACTTTGTATTTTAGACATCTCTTTTGATCATGTGGTGA
GAGGCGGTTCAGGCTTACACGATGAAAATTATATGCGCAGCACCAGCAGAGATAATTATCCCCCAACGGTAAGAGATAAT
ATTGTTGGTTTTCGTTGTGTAAAAAACATTACAGAGTAG

Upstream 100 bases:

>100_bases
TTGCTGCAACAAGACCTGAAGATATTGAATACCTTGGTATCGCAATTTATGGCACCAAAAAAATCATCAATAAACACACG
GGAAACTTGGGGTTAATAAG

Downstream 100 bases:

>100_bases
GTTGTGAGGTTGTATGGAACAATTTGAAAAGACCCCTTTTATTGAGAAAAAACCGTCGTCTCTAAGATATTATCAAGAAG
GGCCACAAGAAACGCATGAA

Product: NirV precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSIMNNMVLISGQPYQRGSILSSDEQPIKTISLSPFFMDIHPVLNKDYRVFIEQGGYSDPRYWSTTGFKFIQEHNITEPL
YWNDPNWNGDKKPVTGISWYEAQAFACFVGKELPTESQWEYAAKGNDNRMYPWGNTEPDLNIANFAPDCEPVEFNRSSTD
WDAHPQNRSPFGCIDMGGNLAEWCLDNYLPNYAWDDNHVDPLCILDISFDHVVRGGSGLHDENYMRSTSRDNYPPTVRDN
IVGFRCVKNITE

Sequences:

>Translated_252_residues
MSIMNNMVLISGQPYQRGSILSSDEQPIKTISLSPFFMDIHPVLNKDYRVFIEQGGYSDPRYWSTTGFKFIQEHNITEPL
YWNDPNWNGDKKPVTGISWYEAQAFACFVGKELPTESQWEYAAKGNDNRMYPWGNTEPDLNIANFAPDCEPVEFNRSSTD
WDAHPQNRSPFGCIDMGGNLAEWCLDNYLPNYAWDDNHVDPLCILDISFDHVVRGGSGLHDENYMRSTSRDNYPPTVRDN
IVGFRCVKNITE
>Mature_251_residues
SIMNNMVLISGQPYQRGSILSSDEQPIKTISLSPFFMDIHPVLNKDYRVFIEQGGYSDPRYWSTTGFKFIQEHNITEPLY
WNDPNWNGDKKPVTGISWYEAQAFACFVGKELPTESQWEYAAKGNDNRMYPWGNTEPDLNIANFAPDCEPVEFNRSSTDW
DAHPQNRSPFGCIDMGGNLAEWCLDNYLPNYAWDDNHVDPLCILDISFDHVVRGGSGLHDENYMRSTSRDNYPPTVRDNI
VGFRCVKNITE

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248087, Length=270, Percent_Identity=28.1481481481481, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI194248088, Length=278, Percent_Identity=27.3381294964029, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194248090, Length=136, Percent_Identity=32.3529411764706, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI257470975, Length=260, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI38202250, Length=284, Percent_Identity=26.056338028169, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20130397, Length=262, Percent_Identity=28.2442748091603, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 28958; Mature: 28827

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIMNNMVLISGQPYQRGSILSSDEQPIKTISLSPFFMDIHPVLNKDYRVFIEQGGYSDP
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECHHHCCCEEEEEECCCCCCC
RYWSTTGFKFIQEHNITEPLYWNDPNWNGDKKPVTGISWYEAQAFACFVGKELPTESQWE
CEECCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEHHHCEEEEEECCCCCCCCCCE
YAAKGNDNRMYPWGNTEPDLNIANFAPDCEPVEFNRSSTDWDAHPQNRSPFGCIDMGGNL
EEECCCCCEECCCCCCCCCCEECCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEECCCCH
AEWCLDNYLPNYAWDDNHVDPLCILDISFDHVVRGGSGLHDENYMRSTSRDNYPPTVRDN
HHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHCCCCCCCCCHHHHHHCCCCCCCCCHHHC
IVGFRCVKNITE
CHHHHHHHHHCC
>Mature Secondary Structure 
SIMNNMVLISGQPYQRGSILSSDEQPIKTISLSPFFMDIHPVLNKDYRVFIEQGGYSDP
CCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECHHHCCCEEEEEECCCCCCC
RYWSTTGFKFIQEHNITEPLYWNDPNWNGDKKPVTGISWYEAQAFACFVGKELPTESQWE
CEECCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEHHHCEEEEEECCCCCCCCCCE
YAAKGNDNRMYPWGNTEPDLNIANFAPDCEPVEFNRSSTDWDAHPQNRSPFGCIDMGGNL
EEECCCCCEECCCCCCCCCCEECCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEECCCCH
AEWCLDNYLPNYAWDDNHVDPLCILDISFDHVVRGGSGLHDENYMRSTSRDNYPPTVRDN
HHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHCCCCCCCCCHHHHHHCCCCCCCCCHHHC
IVGFRCVKNITE
CHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]