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The map label for this gene is rrt

Identifier: 59711651

GI number: 59711651

Start: 1151061

End: 1152248

Strand: Direct

Name: rrt

Synonym: VF_1044

Alternate gene names: NA

Gene position: 1151061-1152248 (Clockwise)

Preceding gene: 59711650

Following gene: 59711652

Centisome position: 39.73

GC content: 32.41

Gene sequence:

>1188_bases
ATGTATCAATTAGAACCTATCAAAAAAACCAAGCAAGTCATCGCCTCAATTCCTAATTTATGTTCTGCTTTAGATATAAC
TATTGATGAGTTGAATAAAGCTCTATCACTATCTTCTGAAGAACGCTATGTTCAAGGGAAAGTTTCAAAAAGTGATGGTA
GCTATCGAGATGTTTATAATCCTCATAATCTAATCAGAAAGATTCAGCGACGGATTAATCGTAGAATTTTTATAAAATTA
GTGGGCTGGCCTAGTTATATATTTGGTTCGATACCAAATAATATAGATAAAAATGGTAAGGTATTAGAAGCCAAAGATTA
TGTAAACTGTGCTGCTCAGCATTGTTTAGCAAAAAGCTTGTTAAAGATGGATCTTAAAGATTTTTTTAACAATATTCATA
TAGATCATGTCAAAGAAATGTTTGAGAAATTTTTTAACTATCCTAAAGATGTTTCTGAGGCATTAAGCAATATTTGCTGT
AGAGGGGACTCTCTGGTTCAAGGAGCCTTAACATCAAGTTATATAGCAAGTTTGTGTTTATGGGATCTTGAGCCACATTT
AGTTAAAAGACTAAAAAGAAAGCAGCTAATTTATACAAGATTAGTTGATGATATAACTGTGTCTTCTAAAATATCAAACT
TTCAGTTTGATATGACTATTGAGCATATTACATCTATGCTACATGAAATGGATTTACCAATAAATAATAGTAAAACCAAG
GTTGCTTATACATCAATTGAACCTTTAACAGTACATGGAATGAGAGTTAACTTTAAAGAACCAAGATACCCATCAGACGA
AGTTAGAAGGCTAAGAGCTGCCGTTCATAATATTGAAAGTTTAGCCTCAGAGCCCGGTTATAGAGTAACATTTGCATATA
GAAAAGATTTTAACCGATGTATGGGACGTGTTAATAAACTAAAAAGGGTTGAACATGAAAAGCACCAAACATTGGTTAAT
AAATTATTAAAAATCCTTCCTCTTCCATCGGAAAAGGATTTAAAACGTTGTAAGGCATCCATTCTTCGGTTAGAAACTGA
TTTCCCGCTTAAAGGTGATACGTATTGGTACAGGAAGCGGTTTTATATCGTTCATGATCGATTAAATGTGTTGCAAAGAA
CTTATAAGAGAACGGCGTTGAAATTAAGAAATAGAATGAAACCAATTAGGCCTGAATATGATGATTAA

Upstream 100 bases:

>100_bases
CTAAACGGTGGCTGTTTACAAATATTATCGATGAATGCAACACCGTTTGTTAATCTCTAGAGTATGAGTGGCTAGGCCTT
TATTGTGCTAAAGTGGAATT

Downstream 100 bases:

>100_bases
AATAATAAATTCGAACAAAGCACTTCGAAATCTTGTTTTCATATTTATATTTGTTGGTGCTATTGGTCTTTTGTTGTCTT
TATTATCAATAATCATGACT

Product: reverse transcriptase

Products: NA

Alternate protein names: EC86-RT; Reverse transcriptase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MYQLEPIKKTKQVIASIPNLCSALDITIDELNKALSLSSEERYVQGKVSKSDGSYRDVYNPHNLIRKIQRRINRRIFIKL
VGWPSYIFGSIPNNIDKNGKVLEAKDYVNCAAQHCLAKSLLKMDLKDFFNNIHIDHVKEMFEKFFNYPKDVSEALSNICC
RGDSLVQGALTSSYIASLCLWDLEPHLVKRLKRKQLIYTRLVDDITVSSKISNFQFDMTIEHITSMLHEMDLPINNSKTK
VAYTSIEPLTVHGMRVNFKEPRYPSDEVRRLRAAVHNIESLASEPGYRVTFAYRKDFNRCMGRVNKLKRVEHEKHQTLVN
KLLKILPLPSEKDLKRCKASILRLETDFPLKGDTYWYRKRFYIVHDRLNVLQRTYKRTALKLRNRMKPIRPEYDD

Sequences:

>Translated_395_residues
MYQLEPIKKTKQVIASIPNLCSALDITIDELNKALSLSSEERYVQGKVSKSDGSYRDVYNPHNLIRKIQRRINRRIFIKL
VGWPSYIFGSIPNNIDKNGKVLEAKDYVNCAAQHCLAKSLLKMDLKDFFNNIHIDHVKEMFEKFFNYPKDVSEALSNICC
RGDSLVQGALTSSYIASLCLWDLEPHLVKRLKRKQLIYTRLVDDITVSSKISNFQFDMTIEHITSMLHEMDLPINNSKTK
VAYTSIEPLTVHGMRVNFKEPRYPSDEVRRLRAAVHNIESLASEPGYRVTFAYRKDFNRCMGRVNKLKRVEHEKHQTLVN
KLLKILPLPSEKDLKRCKASILRLETDFPLKGDTYWYRKRFYIVHDRLNVLQRTYKRTALKLRNRMKPIRPEYDD
>Mature_395_residues
MYQLEPIKKTKQVIASIPNLCSALDITIDELNKALSLSSEERYVQGKVSKSDGSYRDVYNPHNLIRKIQRRINRRIFIKL
VGWPSYIFGSIPNNIDKNGKVLEAKDYVNCAAQHCLAKSLLKMDLKDFFNNIHIDHVKEMFEKFFNYPKDVSEALSNICC
RGDSLVQGALTSSYIASLCLWDLEPHLVKRLKRKQLIYTRLVDDITVSSKISNFQFDMTIEHITSMLHEMDLPINNSKTK
VAYTSIEPLTVHGMRVNFKEPRYPSDEVRRLRAAVHNIESLASEPGYRVTFAYRKDFNRCMGRVNKLKRVEHEKHQTLVN
KLLKILPLPSEKDLKRCKASILRLETDFPLKGDTYWYRKRFYIVHDRLNVLQRTYKRTALKLRNRMKPIRPEYDD

Specific function: Participates in the synthesis of a msDNA (a branched RNA linked by a 2',5'-phosphodiester linkage to a single-stranded DNA) of unknown function. The retron transcript serves as primer and template to the reaction, and codes for the RT [H]

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000123
- InterPro:   IPR000477 [H]

Pfam domain/function: PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 46274; Mature: 46274

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQLEPIKKTKQVIASIPNLCSALDITIDELNKALSLSSEERYVQGKVSKSDGSYRDVYN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCC
PHNLIRKIQRRINRRIFIKLVGWPSYIFGSIPNNIDKNGKVLEAKDYVNCAAQHCLAKSL
HHHHHHHHHHHHCCEEEEEEECCHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
LKMDLKDFFNNIHIDHVKEMFEKFFNYPKDVSEALSNICCRGDSLVQGALTSSYIASLCL
HHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
WDLEPHLVKRLKRKQLIYTRLVDDITVSSKISNFQFDMTIEHITSMLHEMDLPINNSKTK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCCCCCE
VAYTSIEPLTVHGMRVNFKEPRYPSDEVRRLRAAVHNIESLASEPGYRVTFAYRKDFNRC
EEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
MGRVNKLKRVEHEKHQTLVNKLLKILPLPSEKDLKRCKASILRLETDFPLKGDTYWYRKR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEHEE
FYIVHDRLNVLQRTYKRTALKLRNRMKPIRPEYDD
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MYQLEPIKKTKQVIASIPNLCSALDITIDELNKALSLSSEERYVQGKVSKSDGSYRDVYN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCC
PHNLIRKIQRRINRRIFIKLVGWPSYIFGSIPNNIDKNGKVLEAKDYVNCAAQHCLAKSL
HHHHHHHHHHHHCCEEEEEEECCHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
LKMDLKDFFNNIHIDHVKEMFEKFFNYPKDVSEALSNICCRGDSLVQGALTSSYIASLCL
HHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
WDLEPHLVKRLKRKQLIYTRLVDDITVSSKISNFQFDMTIEHITSMLHEMDLPINNSKTK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCCCCCE
VAYTSIEPLTVHGMRVNFKEPRYPSDEVRRLRAAVHNIESLASEPGYRVTFAYRKDFNRC
EEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
MGRVNKLKRVEHEKHQTLVNKLLKILPLPSEKDLKRCKASILRLETDFPLKGDTYWYRKR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEHEE
FYIVHDRLNVLQRTYKRTALKLRNRMKPIRPEYDD
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2466573; 1722556 [H]