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The map label for this gene is ruvA

Identifier: 59711558

GI number: 59711558

Start: 1046930

End: 1047553

Strand: Direct

Name: ruvA

Synonym: VF_0951

Alternate gene names: 59711558

Gene position: 1046930-1047553 (Clockwise)

Preceding gene: 59711557

Following gene: 59711559

Centisome position: 36.13

GC content: 39.58

Gene sequence:

>624_bases
GTGATTGGACGTCTTCGCGGAAATTTATTAGAAAAACAACCACCAGAATTATTAATTGAAGTGAGTGGTATTGGCTATGA
AGTACAGATGCCAATGAGCTGTTTTTATGAATTACCAGAAGTTGGTTCGGAAGCCATTATTTATACTCATTATGTTGTAC
GTGAAGATGCACAGCTACTATATGGTTTTAATACTAAAAATGAACGAGCGTTGTTTCGTGAAGTAATTAAAGCAAATGGT
GTTGGTCCTAAACTGGGCTTAGCTATTCTATCAGGAATGACGGCAGCGCAATTTGTGCAAAGTGTTGAACGTGAAGATAT
CTCAACTTTAGTTAAGTTACCGGGTGTTGGTAAAAAGACAGCGGAAAGACTTGTTGTTGAAATGAAAGATAGATTAAAAG
GATGGGGAGCGGGTGATCTGTTTACGCCAGCGACCGATGCCGCGCCAATGGATGATGGTTCAGAATTTATCACATCTCCA
CAAAGTGCTGTGGATGAAGCGGTTAGTGCATTAATTGCATTAGGTTATAAACCTCAGCAAGCATCTAAGACTGTTTCTCA
AATTGCTAAGCCGGACATGACCAGCGAAGTATTGATCCGTGAATCATTAAAGTCGATGATTTAA

Upstream 100 bases:

>100_bases
ACCAGTGTCGCTTGTTATAAATTCTCATTTCTTTTACTGGATATCTATCCAGTTCTTTATTACTATCTTAACTTATTATT
TATTTTAAAGAGTATCTATT

Downstream 100 bases:

>100_bases
TCATCTTCTAATTGTTGAGTACTTATTATGATTGAAGCTGATCGTTTAATTGCAGCAGATAACCCAACTTTTCGTGAAGA
GGATGTGATTGATAGAGCCA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPEVGSEAIIYTHYVVREDAQLLYGFNTKNERALFREVIKANG
VGPKLGLAILSGMTAAQFVQSVEREDISTLVKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPATDAAPMDDGSEFITSP
QSAVDEAVSALIALGYKPQQASKTVSQIAKPDMTSEVLIRESLKSMI

Sequences:

>Translated_207_residues
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPEVGSEAIIYTHYVVREDAQLLYGFNTKNERALFREVIKANG
VGPKLGLAILSGMTAAQFVQSVEREDISTLVKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPATDAAPMDDGSEFITSP
QSAVDEAVSALIALGYKPQQASKTVSQIAKPDMTSEVLIRESLKSMI
>Mature_207_residues
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPEVGSEAIIYTHYVVREDAQLLYGFNTKNERALFREVIKANG
VGPKLGLAILSGMTAAQFVQSVEREDISTLVKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPATDAAPMDDGSEFITSP
QSAVDEAVSALIALGYKPQQASKTVSQIAKPDMTSEVLIRESLKSMI

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=212, Percent_Identity=66.9811320754717, Blast_Score=290, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_VIBF1 (Q5E6A0)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_204334.1
- ProteinModelPortal:   Q5E6A0
- SMR:   Q5E6A0
- STRING:   Q5E6A0
- GeneID:   3278001
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0951
- NMPDR:   fig|312309.3.peg.800
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q5E6A0
- ProtClustDB:   PRK00116
- BioCyc:   VFIS312309:VF0951-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22565; Mature: 22565

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPEVGSEAIIYTHYVVREDAQLL
CCCCCCCCHHCCCCCCEEEEECCCCEEEECCHHHHHHHHCCCCCEEEEHHHHHHCCCHHE
YGFNTKNERALFREVIKANGVGPKLGLAILSGMTAAQFVQSVEREDISTLVKLPGVGKKT
ECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLVVEMKDRLKGWGAGDLFTPATDAAPMDDGSEFITSPQSAVDEAVSALIALGYKPQQ
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCH
ASKTVSQIAKPDMTSEVLIRESLKSMI
HHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPEVGSEAIIYTHYVVREDAQLL
CCCCCCCCHHCCCCCCEEEEECCCCEEEECCHHHHHHHHCCCCCEEEEHHHHHHCCCHHE
YGFNTKNERALFREVIKANGVGPKLGLAILSGMTAAQFVQSVEREDISTLVKLPGVGKKT
ECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLVVEMKDRLKGWGAGDLFTPATDAAPMDDGSEFITSPQSAVDEAVSALIALGYKPQQ
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCH
ASKTVSQIAKPDMTSEVLIRESLKSMI
HHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA