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The map label for this gene is msrB [H]

Identifier: 59711521

GI number: 59711521

Start: 1008822

End: 1009229

Strand: Direct

Name: msrB [H]

Synonym: VF_0914

Alternate gene names: 59711521

Gene position: 1008822-1009229 (Clockwise)

Preceding gene: 59711518

Following gene: 59711523

Centisome position: 34.82

GC content: 36.27

Gene sequence:

>408_bases
ATGGAGACACAAAAAACATTTTTAGAATACACCGATGAAGAGTGGCGAAAAAAGCTTACAAAAGAAGAGTTTGATATTTG
TAGAAAACAAGGAACAGAAGCGCCTTTCTCAGGAACGTTATTACATAATAAAGAAAAAGGCTATTACGCCTGTACTTGTT
GCCAAACCATTTTATTTGTATCTGATAATAAATATGACTCAGGTTGTGGGTGGCCAAGCTTTGATGCCCCAGTGAACGAT
CAAGTCATAAGATATATTGAAGATAACAGCCACGGGATGAAAAGAATTGAAATCCGCTGTCGTCATTGTGATAGTCATTT
AGGGCATGTTTTTGATGATGGCCCCAAAACAACCAACGAAAGATATTGCGTGAATTCGGTTTCTTTAAATTTTTCGCAAG
ATAAATAA

Upstream 100 bases:

>100_bases
CGCTTGGTTGCTGTAAAATTACTTTGGCAAAGTATGTGCTACAAAGGTGATATATAGCAAGGTTTAATTTAAAGAAGTCT
AAGAAAGGAGTTTTATAAAA

Downstream 100 bases:

>100_bases
ATCCATATAAAATAAAAAAGGAGCACATTTCGGCTCCTTTTTTATTTACATCAGTAAATTAATTTTTCTCAGCTATCTTT
GGTAGTAGCTGTGCTGAGAA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
METQKTFLEYTDEEWRKKLTKEEFDICRKQGTEAPFSGTLLHNKEKGYYACTCCQTILFVSDNKYDSGCGWPSFDAPVND
QVIRYIEDNSHGMKRIEIRCRHCDSHLGHVFDDGPKTTNERYCVNSVSLNFSQDK

Sequences:

>Translated_135_residues
METQKTFLEYTDEEWRKKLTKEEFDICRKQGTEAPFSGTLLHNKEKGYYACTCCQTILFVSDNKYDSGCGWPSFDAPVND
QVIRYIEDNSHGMKRIEIRCRHCDSHLGHVFDDGPKTTNERYCVNSVSLNFSQDK
>Mature_135_residues
METQKTFLEYTDEEWRKKLTKEEFDICRKQGTEAPFSGTLLHNKEKGYYACTCCQTILFVSDNKYDSGCGWPSFDAPVND
QVIRYIEDNSHGMKRIEIRCRHCDSHLGHVFDDGPKTTNERYCVNSVSLNFSQDK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI37620216, Length=123, Percent_Identity=45.5284552845528, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI301336164, Length=123, Percent_Identity=45.5284552845528, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI301336162, Length=123, Percent_Identity=45.5284552845528, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI73089054, Length=123, Percent_Identity=45.5284552845528, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI117606353, Length=136, Percent_Identity=46.3235294117647, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1788077, Length=122, Percent_Identity=59.8360655737705, Blast_Score=161, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17553450, Length=135, Percent_Identity=47.4074074074074, Blast_Score=131, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=135, Percent_Identity=47.4074074074074, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319816, Length=141, Percent_Identity=39.7163120567376, Blast_Score=102, Evalue=3e-23,
Organism=Drosophila melanogaster, GI221378664, Length=132, Percent_Identity=42.4242424242424, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI221378662, Length=139, Percent_Identity=40.2877697841727, Blast_Score=122, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24645799, Length=132, Percent_Identity=42.4242424242424, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45553335, Length=132, Percent_Identity=42.4242424242424, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21356369, Length=132, Percent_Identity=42.4242424242424, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24645801, Length=143, Percent_Identity=39.8601398601399, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24645804, Length=143, Percent_Identity=39.8601398601399, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15721; Mature: 15721

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
5.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQKTFLEYTDEEWRKKLTKEEFDICRKQGTEAPFSGTLLHNKEKGYYACTCCQTILFV
CCCHHHHHHCCCHHHHHHHCHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEHHHHHHHHC
SDNKYDSGCGWPSFDAPVNDQVIRYIEDNSHGMKRIEIRCRHCDSHLGHVFDDGPKTTNE
CCCCCCCCCCCCCCCCCCCCHHEEEECCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCC
RYCVNSVSLNFSQDK
EEEEEEEEEECCCCC
>Mature Secondary Structure
METQKTFLEYTDEEWRKKLTKEEFDICRKQGTEAPFSGTLLHNKEKGYYACTCCQTILFV
CCCHHHHHHCCCHHHHHHHCHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEHHHHHHHHC
SDNKYDSGCGWPSFDAPVNDQVIRYIEDNSHGMKRIEIRCRHCDSHLGHVFDDGPKTTNE
CCCCCCCCCCCCCCCCCCCCHHEEEECCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCC
RYCVNSVSLNFSQDK
EEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]