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The map label for this gene is glnS [H]

Identifier: 59711416

GI number: 59711416

Start: 889209

End: 890867

Strand: Direct

Name: glnS [H]

Synonym: VF_0809

Alternate gene names: 59711416

Gene position: 889209-890867 (Clockwise)

Preceding gene: 59711415

Following gene: 59711418

Centisome position: 30.69

GC content: 39.42

Gene sequence:

>1659_bases
ATGAGTGAAACTGAAACTCGTCCTACCAACTTTATCCGTCAAATTATTGATGAAGATTTAAAGTCTGGTAAACATTCCAG
TGTCCATACTCGTTTCCCGCCAGAGCCAAATGGCTATCTGCATATCGGACACGCAAAATCTATCTGTTTGAATTTTGGTA
TTGCTCAAGATTATCAGGGTCAGTGTAATCTTCGTTTTGACGATACAAACCCTGAGAAAGAAGACATCGAATACGTTGAG
TCTATTAAGAATGACGTTAACTGGTTAGGTTTTCAGTGGAGTGGAGATATTCAATATTCTTCAAACTACTTTGATAAGCT
ATATGGTTATGCTGTTGAATTAATTGAAAAAGGATTAGCGTATGTTGATGAGCTAACTCCTGAGCAAATGCGTGAATACC
GTGGTTCTCTAAAAGAGCCAGGTAAAAACAGCCCGTACCGTGATCGTAGCGTAGAAGAAAACCTAGCGTTATTTGAACAA
ATGCGTGATGGTAAATTTAAAGAAGGCACAATTTGCTTACGAGCTAAAATTGATATGGCTTCTTCATTCATCGTACTTCG
TGATCCTGTTATTTATCGTGTACGTTTTGCTACTCACCATCAAACTGGTGATAAGTGGTGCATTTACCCAATGTACGACT
TCACACACTGTATTTCTGATGCGTTAGAAGGCATTACGCACTCTATTTGTACGCTTGAATTCCAAGACAACCGTCGTTTA
TACGATTGGGTACTAGAGAACATCACAATTGATTGCCAACCGCGTCAATATGAATTTAGCCGTCTAAATCTTGAATATAC
GGTAATGTCTAAGCGTAAGCTGAACCAACTAGTGACTGAGAAATTAGTAAATGGTTGGGATGACCCACGTATGCCTACTG
TTTCTGGTTTACGTCGTCGTGGCTTTACTTCTGCATCAATTCGCGAGTTCTGTAAGCGTATCGGTGTAACGAAACAAGAA
AACATGATTGAATTCAGCTCTCTTGAGTCTTGTATTCGCGATGATTTAAACGAATCAGCACCTCGTGCAATGGCTGTTCT
TGAGCCAGTGAAACTTGTGATTGAAAACTACGAAGAAGGTAAGGTTGAGACGCTAAATATTGCTAACCATCCAAATAAAC
CTGAAATGGGCACTCGTGAAGTACCATTTACTCGTGAAGTTTATATTGAACAAGATGATTTCCGCGAAGAAGCGAACAAA
AAATACAAGCGTTTAGTGCTAGGTAAAGAAGTTCGTTTACGTGGTGCTTACGTTATTCAAGCTAACCGTATTGAAAAAGA
CGAAGCAGGTAATATCACAACGATTTTCTGTAGTTACGATGAAGATACGTTAGGTAAAAACCCTGCAGATGGTCGTAAAG
TTAAAGGTGTTATTCACTGGGTTTCTGCTGATAAAGCATTACCAGCTGAAATTCGTTTATACGATCGTTTATTTACTGTA
CCAAACCCAGGTGCTGCGGATGATTTTGCTGCAACAATCAACCCTGAGTCTTTAGTGGTTAAAAATGGTTTTGTTGAACC
TAGTTTAGCAACAGCAGAAGCTGAAGTTGGTTATCAGTTTGAGCGTACAGGTTACTTCTGTGCAGATAACAAAGACTCAA
GTGCTGATGCATTAGTCTTTAACCGTACTGTAGGTTTACGTGATACTTGGGCTGGTTAA

Upstream 100 bases:

>100_bases
TTGATTCTATATATTGAGTATCTGCCCATAATTGTGGATCATAGGGAGATATGAACAATCTGTTCTTTCTGACAATACTA
ATACCAATGAGGTGCTTTAG

Downstream 100 bases:

>100_bases
TTAATCATTGCTAGCTAATAAAAAACCAGCATGAAAATGCTGGTTTTTTTATATGAGCTTGTCGCAAAAAGCGATTAATT
AAGCGTTGTGTGCATCATCA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MSETETRPTNFIRQIIDEDLKSGKHSSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPEKEDIEYVE
SIKNDVNWLGFQWSGDIQYSSNYFDKLYGYAVELIEKGLAYVDELTPEQMREYRGSLKEPGKNSPYRDRSVEENLALFEQ
MRDGKFKEGTICLRAKIDMASSFIVLRDPVIYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFQDNRRL
YDWVLENITIDCQPRQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTVSGLRRRGFTSASIREFCKRIGVTKQE
NMIEFSSLESCIRDDLNESAPRAMAVLEPVKLVIENYEEGKVETLNIANHPNKPEMGTREVPFTREVYIEQDDFREEANK
KYKRLVLGKEVRLRGAYVIQANRIEKDEAGNITTIFCSYDEDTLGKNPADGRKVKGVIHWVSADKALPAEIRLYDRLFTV
PNPGAADDFAATINPESLVVKNGFVEPSLATAEAEVGYQFERTGYFCADNKDSSADALVFNRTVGLRDTWAG

Sequences:

>Translated_552_residues
MSETETRPTNFIRQIIDEDLKSGKHSSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPEKEDIEYVE
SIKNDVNWLGFQWSGDIQYSSNYFDKLYGYAVELIEKGLAYVDELTPEQMREYRGSLKEPGKNSPYRDRSVEENLALFEQ
MRDGKFKEGTICLRAKIDMASSFIVLRDPVIYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFQDNRRL
YDWVLENITIDCQPRQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTVSGLRRRGFTSASIREFCKRIGVTKQE
NMIEFSSLESCIRDDLNESAPRAMAVLEPVKLVIENYEEGKVETLNIANHPNKPEMGTREVPFTREVYIEQDDFREEANK
KYKRLVLGKEVRLRGAYVIQANRIEKDEAGNITTIFCSYDEDTLGKNPADGRKVKGVIHWVSADKALPAEIRLYDRLFTV
PNPGAADDFAATINPESLVVKNGFVEPSLATAEAEVGYQFERTGYFCADNKDSSADALVFNRTVGLRDTWAG
>Mature_551_residues
SETETRPTNFIRQIIDEDLKSGKHSSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPEKEDIEYVES
IKNDVNWLGFQWSGDIQYSSNYFDKLYGYAVELIEKGLAYVDELTPEQMREYRGSLKEPGKNSPYRDRSVEENLALFEQM
RDGKFKEGTICLRAKIDMASSFIVLRDPVIYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFQDNRRLY
DWVLENITIDCQPRQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTVSGLRRRGFTSASIREFCKRIGVTKQEN
MIEFSSLESCIRDDLNESAPRAMAVLEPVKLVIENYEEGKVETLNIANHPNKPEMGTREVPFTREVYIEQDDFREEANKK
YKRLVLGKEVRLRGAYVIQANRIEKDEAGNITTIFCSYDEDTLGKNPADGRKVKGVIHWVSADKALPAEIRLYDRLFTVP
NPGAADDFAATINPESLVVKNGFVEPSLATAEAEVGYQFERTGYFCADNKDSSADALVFNRTVGLRDTWAG

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=527, Percent_Identity=46.6793168880455, Blast_Score=454, Evalue=1e-128,
Organism=Homo sapiens, GI62241042, Length=517, Percent_Identity=34.4294003868472, Blast_Score=292, Evalue=7e-79,
Organism=Escherichia coli, GI1786895, Length=551, Percent_Identity=80.0362976406534, Blast_Score=952, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=210, Percent_Identity=27.6190476190476, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=533, Percent_Identity=43.9024390243902, Blast_Score=442, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17511007, Length=520, Percent_Identity=34.0384615384615, Blast_Score=268, Evalue=6e-72,
Organism=Saccharomyces cerevisiae, GI6324742, Length=562, Percent_Identity=43.4163701067616, Blast_Score=406, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321192, Length=544, Percent_Identity=35.8455882352941, Blast_Score=310, Evalue=4e-85,
Organism=Drosophila melanogaster, GI17864488, Length=528, Percent_Identity=44.1287878787879, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24649466, Length=516, Percent_Identity=35.6589147286822, Blast_Score=276, Evalue=2e-74,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 63395; Mature: 63264

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETETRPTNFIRQIIDEDLKSGKHSSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQG
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHEEEEECCCCCCCCC
QCNLRFDDTNPEKEDIEYVESIKNDVNWLGFQWSGDIQYSSNYFDKLYGYAVELIEKGLA
CEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHH
YVDELTPEQMREYRGSLKEPGKNSPYRDRSVEENLALFEQMRDGKFKEGTICLRAKIDMA
HHHHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
SSFIVLRDPVIYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFQDNRRL
CCEEEEECCEEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHEEEEEECCCCHH
YDWVLENITIDCQPRQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTVSGLRRR
HHHHHHCCEEECCCCCEEHEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHC
GFTSASIREFCKRIGVTKQENMIEFSSLESCIRDDLNESAPRAMAVLEPVKLVIENYEEG
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
KVETLNIANHPNKPEMGTREVPFTREVYIEQDDFREEANKKYKRLVLGKEVRLRGAYVIQ
CEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
ANRIEKDEAGNITTIFCSYDEDTLGKNPADGRKVKGVIHWVSADKALPAEIRLYDRLFTV
ECCCCCCCCCCEEEEEEECCCHHCCCCCCCCCEEEEEEEEEECCCCCCHHHEEEHHEEEC
PNPGAADDFAATINPESLVVKNGFVEPSLATAEAEVGYQFERTGYFCADNKDSSADALVF
CCCCCCCCCEEECCCCEEEEECCCCCCCCCCCHHHCCEEEECCCEEEECCCCCCCCEEEE
NRTVGLRDTWAG
EECCCCCCCCCC
>Mature Secondary Structure 
SETETRPTNFIRQIIDEDLKSGKHSSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHEEEEECCCCCCCCC
QCNLRFDDTNPEKEDIEYVESIKNDVNWLGFQWSGDIQYSSNYFDKLYGYAVELIEKGLA
CEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHH
YVDELTPEQMREYRGSLKEPGKNSPYRDRSVEENLALFEQMRDGKFKEGTICLRAKIDMA
HHHHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
SSFIVLRDPVIYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFQDNRRL
CCEEEEECCEEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHEEEEEECCCCHH
YDWVLENITIDCQPRQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTVSGLRRR
HHHHHHCCEEECCCCCEEHEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHC
GFTSASIREFCKRIGVTKQENMIEFSSLESCIRDDLNESAPRAMAVLEPVKLVIENYEEG
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
KVETLNIANHPNKPEMGTREVPFTREVYIEQDDFREEANKKYKRLVLGKEVRLRGAYVIQ
CEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
ANRIEKDEAGNITTIFCSYDEDTLGKNPADGRKVKGVIHWVSADKALPAEIRLYDRLFTV
ECCCCCCCCCCEEEEEEECCCHHCCCCCCCCCEEEEEEEEEECCCCCCHHHEEEHHEEEC
PNPGAADDFAATINPESLVVKNGFVEPSLATAEAEVGYQFERTGYFCADNKDSSADALVF
CCCCCCCCCEEECCCCEEEEECCCCCCCCCCCHHHCCEEEECCCEEEECCCCCCCCEEEE
NRTVGLRDTWAG
EECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA