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The map label for this gene is nqrA [H]

Identifier: 59711332

GI number: 59711332

Start: 791680

End: 793077

Strand: Direct

Name: nqrA [H]

Synonym: VF_0725

Alternate gene names: 59711332

Gene position: 791680-793077 (Clockwise)

Preceding gene: 59711331

Following gene: 59711333

Centisome position: 27.32

GC content: 41.85

Gene sequence:

>1398_bases
ATGCAGTGTCGTGTCTTATATAGAATCTTTTTTCCCATAAAATTAGTGCAAGTGCGTATGATTACAATAAAAAAGGGTTT
GGATCTTCCTATTGCAGGTGTTCCTACTCAGGTGATTAATGATGGTAAATCCATCACTAAAGTCGCCTTGCTTGGCGAAG
AGTACGTTGGTATGCGTCCTACGATGCATGTCCGCGTGGAAGATGTAGTAAAGAAAGGTCAGGTTCTTTTTGCAGATAAA
AAGAATCCAGGCGTAGTATTTACTGCTCCAGTAAGTGGTAAGGTTGTTGAAATTAACCGTGGTGCGAAGCGCGTACTTCA
ATCTGTAGTAATTGCAGTTGAAGGCGAAGAGCAGGTTACTTTTAATAGCTATGCAGCAAATGAACTAGTGTCGCTTGATC
GTGAAACGATCAAAACACAACTGGTTGATTCAGGTGCATGGACTGCATTACGTACTCGTCCGTTCAGCAAGGTTCCAGCG
ATTGATTCTGAAACAAAGGCTATCTTTGTTACTGCTATGGATACTAATCCACTAGCGGCTGATGCAGAAGTGATCATTAA
CCAACAAGAAGAAGCCTTTATTGCAGGCCTAGACCTATTATCTGTATTAACAGGTGATAAAGTTTACGTATGTAAGAAAG
GAGGTAGCTTACCTCGTTCTTCTCAAAAAAATGTTGAAGAACATGTATTTGATGGCCCTCATCCAGCTGGTTTAGCCGGT
ACTCACATGCATTACTTGTATCCTGTTGATACAAATCATGTAGCGTGGAGCATTGGTTACCAAGATGTGATTGCATTCGG
TCAACTGTTCTTAACGGGTGAAATCTACTCTGAAAGAATCGTATCTTTAGCTGGCCCTGCAGTAAATAATCCTCGTTTAG
TTCGTACTATTACTGGTGCAAGCTTAGTTGATTTAACTGACAGTGAAGTAATGCCTGGTGAGATTCGTGTGATTTCTGGT
TCTGTACTTAACGGTACGCAAGCATCAGGTCCTCACGCTTACCTTGGTCGTTACCATCAGCAAGTTTCTGTTCTTCGTGA
AGGTCGTGAGAAAGAATTGTTTGGTTGGGCTGTTCCTGGCAAAAACAAATTCTCAGTAACTCGTTCATTCTTGAGTCACT
TATTCTCAGGTCAACTGTTTAACATGACGACAACTACTAACGGTAGTGATCGTGCAATGGTGCCAATCGGTAACTACGAA
CGCGTATTACCATTAGACATGGAAGCAACCATGTTATTGCGTGACCTTTGTGCTGGTGATGTTGACAGTGCACAACGCTT
AGGTGCATTAGAGTTAGATGAAGAAGATCTAGGTCTATGTACATATGTGTGCCCTGGTAAATATGAGTATGGTCCAATGC
TTCGTGAGATCTTGGATACCATCGAGAAGGAAGGGTAA

Upstream 100 bases:

>100_bases
GAATCCTCCGCCTTAAAACAGCTTTTTTCGTATTTATGTAAAAAGCATATTACTAGGATGTTAATAGTGTTGCGCGATTT
GTGTCGTCAATACTGGACAC

Downstream 100 bases:

>100_bases
TTGATGAGCCTTTTAAATTTATTTGAAAAAGTTGAACATCATTTTGAGCCAGGCGGTAAATATGAGAAGTGGTTTGCTTT
ATACGAAGCAACAGCAACAC

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MQCRVLYRIFFPIKLVQVRMITIKKGLDLPIAGVPTQVINDGKSITKVALLGEEYVGMRPTMHVRVEDVVKKGQVLFADK
KNPGVVFTAPVSGKVVEINRGAKRVLQSVVIAVEGEEQVTFNSYAANELVSLDRETIKTQLVDSGAWTALRTRPFSKVPA
IDSETKAIFVTAMDTNPLAADAEVIINQQEEAFIAGLDLLSVLTGDKVYVCKKGGSLPRSSQKNVEEHVFDGPHPAGLAG
THMHYLYPVDTNHVAWSIGYQDVIAFGQLFLTGEIYSERIVSLAGPAVNNPRLVRTITGASLVDLTDSEVMPGEIRVISG
SVLNGTQASGPHAYLGRYHQQVSVLREGREKELFGWAVPGKNKFSVTRSFLSHLFSGQLFNMTTTTNGSDRAMVPIGNYE
RVLPLDMEATMLLRDLCAGDVDSAQRLGALELDEEDLGLCTYVCPGKYEYGPMLREILDTIEKEG

Sequences:

>Translated_465_residues
MQCRVLYRIFFPIKLVQVRMITIKKGLDLPIAGVPTQVINDGKSITKVALLGEEYVGMRPTMHVRVEDVVKKGQVLFADK
KNPGVVFTAPVSGKVVEINRGAKRVLQSVVIAVEGEEQVTFNSYAANELVSLDRETIKTQLVDSGAWTALRTRPFSKVPA
IDSETKAIFVTAMDTNPLAADAEVIINQQEEAFIAGLDLLSVLTGDKVYVCKKGGSLPRSSQKNVEEHVFDGPHPAGLAG
THMHYLYPVDTNHVAWSIGYQDVIAFGQLFLTGEIYSERIVSLAGPAVNNPRLVRTITGASLVDLTDSEVMPGEIRVISG
SVLNGTQASGPHAYLGRYHQQVSVLREGREKELFGWAVPGKNKFSVTRSFLSHLFSGQLFNMTTTTNGSDRAMVPIGNYE
RVLPLDMEATMLLRDLCAGDVDSAQRLGALELDEEDLGLCTYVCPGKYEYGPMLREILDTIEKEG
>Mature_465_residues
MQCRVLYRIFFPIKLVQVRMITIKKGLDLPIAGVPTQVINDGKSITKVALLGEEYVGMRPTMHVRVEDVVKKGQVLFADK
KNPGVVFTAPVSGKVVEINRGAKRVLQSVVIAVEGEEQVTFNSYAANELVSLDRETIKTQLVDSGAWTALRTRPFSKVPA
IDSETKAIFVTAMDTNPLAADAEVIINQQEEAFIAGLDLLSVLTGDKVYVCKKGGSLPRSSQKNVEEHVFDGPHPAGLAG
THMHYLYPVDTNHVAWSIGYQDVIAFGQLFLTGEIYSERIVSLAGPAVNNPRLVRTITGASLVDLTDSEVMPGEIRVISG
SVLNGTQASGPHAYLGRYHQQVSVLREGREKELFGWAVPGKNKFSVTRSFLSHLFSGQLFNMTTTTNGSDRAMVPIGNYE
RVLPLDMEATMLLRDLCAGDVDSAQRLGALELDEEDLGLCTYVCPGKYEYGPMLREILDTIEKEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 50931; Mature: 50931

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCRVLYRIFFPIKLVQVRMITIKKGLDLPIAGVPTQVINDGKSITKVALLGEEYVGMRP
CCEEEEEEEHHHHEEEEEEEEEEECCCCCCCCCCCHHHHCCCCCEEEEEEECHHHCCCCC
TMHVRVEDVVKKGQVLFADKKNPGVVFTAPVSGKVVEINRGAKRVLQSVVIAVEGEEQVT
EEEEEHHHHHHCCCEEEEECCCCCEEEECCCCCEEEEECCHHHHHHHHEEEEECCCCEEE
FNSYAANELVSLDRETIKTQLVDSGAWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLAA
ECCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCC
DAEVIINQQEEAFIAGLDLLSVLTGDKVYVCKKGGSLPRSSQKNVEEHVFDGPHPAGLAG
CHHEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCC
THMHYLYPVDTNHVAWSIGYQDVIAFGQLFLTGEIYSERIVSLAGPAVNNPRLVRTITGA
CCEEEEEEECCCCEEEECCHHHHHHHHHHEEEHHHHHHHHHHHCCCCCCCCEEEEEECCC
SLVDLTDSEVMPGEIRVISGSVLNGTQASGPHAYLGRYHQQVSVLREGREKELFGWAVPG
EEEECCCCCCCCCEEEEEECCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCC
KNKFSVTRSFLSHLFSGQLFNMTTTTNGSDRAMVPIGNYERVLPLDMEATMLLRDLCAGD
CCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCEEEECCCHHHHHHHHHHCCC
VDSAQRLGALELDEEDLGLCTYVCPGKYEYGPMLREILDTIEKEG
CCHHHHCCCEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQCRVLYRIFFPIKLVQVRMITIKKGLDLPIAGVPTQVINDGKSITKVALLGEEYVGMRP
CCEEEEEEEHHHHEEEEEEEEEEECCCCCCCCCCCHHHHCCCCCEEEEEEECHHHCCCCC
TMHVRVEDVVKKGQVLFADKKNPGVVFTAPVSGKVVEINRGAKRVLQSVVIAVEGEEQVT
EEEEEHHHHHHCCCEEEEECCCCCEEEECCCCCEEEEECCHHHHHHHHEEEEECCCCEEE
FNSYAANELVSLDRETIKTQLVDSGAWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLAA
ECCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCC
DAEVIINQQEEAFIAGLDLLSVLTGDKVYVCKKGGSLPRSSQKNVEEHVFDGPHPAGLAG
CHHEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCC
THMHYLYPVDTNHVAWSIGYQDVIAFGQLFLTGEIYSERIVSLAGPAVNNPRLVRTITGA
CCEEEEEEECCCCEEEECCHHHHHHHHHHEEEHHHHHHHHHHHCCCCCCCCEEEEEECCC
SLVDLTDSEVMPGEIRVISGSVLNGTQASGPHAYLGRYHQQVSVLREGREKELFGWAVPG
EEEECCCCCCCCCEEEEEECCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCC
KNKFSVTRSFLSHLFSGQLFNMTTTTNGSDRAMVPIGNYERVLPLDMEATMLLRDLCAGD
CCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCEEEECCCHHHHHHHHHHCCC
VDSAQRLGALELDEEDLGLCTYVCPGKYEYGPMLREILDTIEKEG
CCHHHHCCCEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA