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The map label for this gene is tadA [H]

Identifier: 59711257

GI number: 59711257

Start: 710441

End: 710956

Strand: Direct

Name: tadA [H]

Synonym: VF_0650

Alternate gene names: 59711257

Gene position: 710441-710956 (Clockwise)

Preceding gene: 59711256

Following gene: 59711259

Centisome position: 24.52

GC content: 42.25

Gene sequence:

>516_bases
ATGAGTGTTAAACAAGAAAGCAGAGATGCCAGCTTTTATATGCAACGAGCAATGGAACTGGCTGCTATCGCAGAGCAAGA
GGGTGAAGTTCCTGTTGGTGCTGTGATTGTCTTGGATGATGAAATTATCGGAGAGGGGTGGAATCGCTCAATCAGTACTC
ATGATGCAACTGCTCATGCAGAAATGATGGCAATTAAACAAGCGGGTAGTAAAATTGAAAACTATCGCTTAGTTGATGCG
ACATTATACGTTACGTTAGAGCCATGCCCTATGTGTGCAGGCGCGATTGTACATAGTCGTATTAAACGCGTTATTTTTGG
TGCATCAGATATGAAAACAGGGGCATCAGGAAGCGTGATAAACTTGTTTACTTCAGCAACGGCGTTTCATTTTGTTGAAT
GTGAATCAGGCGTGATGGAAGAGGCATGTCGTTCTCAGTTGCAGGCGTTTTTTAAAAGAAGACGTAAAGAGAAGAAAGAA
GAGAAAAAAGCCAGAAGAGAAGCTGAGCAGAAATAA

Upstream 100 bases:

>100_bases
GCCAAAAGAAGGGATCTGGGCTGTGTACCCAAATAACCGACACCTTTCAACTAAGGTTCGTTTATTGGTTGAATTTTTAG
CACAAGAGCTAGCTGAGTAA

Downstream 100 bases:

>100_bases
AGACGAATAGGATCTAAAAAGGCAAGCCATTATTGGTTTGCCTTTTTCTTTTGTATGTCTATCGACAAGAGAAGGGGTCA
CCTGTGTCGAATAATGCTTG

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSVKQESRDASFYMQRAMELAAIAEQEGEVPVGAVIVLDDEIIGEGWNRSISTHDATAHAEMMAIKQAGSKIENYRLVDA
TLYVTLEPCPMCAGAIVHSRIKRVIFGASDMKTGASGSVINLFTSATAFHFVECESGVMEEACRSQLQAFFKRRRKEKKE
EKKARREAEQK

Sequences:

>Translated_171_residues
MSVKQESRDASFYMQRAMELAAIAEQEGEVPVGAVIVLDDEIIGEGWNRSISTHDATAHAEMMAIKQAGSKIENYRLVDA
TLYVTLEPCPMCAGAIVHSRIKRVIFGASDMKTGASGSVINLFTSATAFHFVECESGVMEEACRSQLQAFFKRRRKEKKE
EKKARREAEQK
>Mature_170_residues
SVKQESRDASFYMQRAMELAAIAEQEGEVPVGAVIVLDDEIIGEGWNRSISTHDATAHAEMMAIKQAGSKIENYRLVDAT
LYVTLEPCPMCAGAIVHSRIKRVIFGASDMKTGASGSVINLFTSATAFHFVECESGVMEEACRSQLQAFFKRRRKEKKEE
KKARREAEQK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=167, Percent_Identity=32.9341317365269, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=54.5454545454545, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI1786616, Length=156, Percent_Identity=31.4102564102564, Blast_Score=62, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541138, Length=176, Percent_Identity=34.6590909090909, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=40.8163265306122, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6325319, Length=104, Percent_Identity=35.5769230769231, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=116, Percent_Identity=33.6206896551724, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=30.8219178082192, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19022; Mature: 18891

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKQESRDASFYMQRAMELAAIAEQEGEVPVGAVIVLDDEIIGEGWNRSISTHDATAHA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHCCCCCCCCCCCCHHHHH
EMMAIKQAGSKIENYRLVDATLYVTLEPCPMCAGAIVHSRIKRVIFGASDMKTGASGSVI
HHHHHHHHCCHHHCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
NLFTSATAFHFVECESGVMEEACRSQLQAFFKRRRKEKKEEKKARREAEQK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVKQESRDASFYMQRAMELAAIAEQEGEVPVGAVIVLDDEIIGEGWNRSISTHDATAHA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHCCCCCCCCCCCCHHHHH
EMMAIKQAGSKIENYRLVDATLYVTLEPCPMCAGAIVHSRIKRVIFGASDMKTGASGSVI
HHHHHHHHCCHHHCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
NLFTSATAFHFVECESGVMEEACRSQLQAFFKRRRKEKKEEKKARREAEQK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]