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The map label for this gene is recD [H]

Identifier: 59711190

GI number: 59711190

Start: 640434

End: 642452

Strand: Direct

Name: recD [H]

Synonym: VF_0583

Alternate gene names: 59711190

Gene position: 640434-642452 (Clockwise)

Preceding gene: 59711189

Following gene: 59711191

Centisome position: 22.1

GC content: 40.66

Gene sequence:

>2019_bases
ATGCTTAAGCAATTACAACACTTAATGGATCATGGTGTACTTCGCCCATTGGATCTTCAATTTGCTAAATTTATCGCTCA
GCAAGAAAAAAACAGTGATAGTAATTTACTTATGTTGCTATCAGCCATTACGAGTCATGAACTAGGTCGTGGTCATGTAT
GTATTGATATTGAGCAGATAGAGCAAGGGGAGCTCTTTACTCTTCCAGCAAAATATCGTGATGCATTATTAGAGTTAGTC
CCTGAAAGAAGCGCTTGGGCAGAACAATTAATTAATGCATCAACTGTCTCAAATGGCACAGAGGCAACCCCTTTAGCTTT
TGATGGTACTCGCTTGTATTTACAACGCTACTGGGCATTTGAACAACGTGTGTCTAACCGTATTACTAAAGCGGCGCAAA
GTGTTGCAGTAAACCCTCAGCTATCGAATACATTGGATGAGTTGTTTGCTCGTCAGTATCATTTTCTATTTTCAGCATTG
AAAAAGTTGGAGAATAACAATCAAGTTTCTCGCCAACAATTAGTGTGCGATATGTTGGATGTTGTTCAATCTGATGATCT
GGATTGGCAGGCGATTGATACGGTGTTATTAGCTGCGACCAAATCTTCAGAATTAGAAACGTTAGATCAATTAATTCCAA
ATAACCACTGTGTGAATTGGCAAAAAGTCGCGGCAGCTGTGGCGTTAACTCGTCGATTCTCAGTAATTTCTGGTGGTCCA
GGTACGGGTAAAACAACCACAGTAACCAAGCTTTTGGCTTCCTTAGTGACACAAGCTAAGCAGGATAATAAGAACATAGC
GATTAAACTGGTTGCGCCAACAGGTAAAGCCGCGGCGCGTTTGACTGAATCCATTGGTCAGGCGGTACAATCCATTGGTT
TAGCACCTGAAGTGAAAGAAGCGATCCCAACAGATGCCAGTACACTACATCGCTTACTTGGTTATATTCCTAATCAAGTG
GATTTTCGTCATAACAAATCCAATCCGTTACACCTTGATGTATTGGTGGTGGATGAAGCGTCTATGGTCGATTTGCCTAT
GATGGCTCGATTACTCGATGCCGTGCCTGAACACGCTCGTGTTATTTTATTGGGTGATAAAGATCAACTCGCTTCAGTTG
AAGCGGGAGCGGTGTTAGGTGATATTTGTCAGTTTACTAAAATGGGTTACAGCCAGAATCAAGCACAGCAATTATCTCAA
CTAACTGGCTTTAATCTATCGGCACAATTACATAATAATGCGGTTGCAGATAGCTTATGTATGCTGCAAAAGAGTTACCG
TTTTGATGCGCGTTCAGGCATAGGTCAGCTTGCCAAAGCAATTAATGAAGGCAGTAAATTTAAAGTAGAAGCTGTGTGGG
ATAAAGGGTTTTCAGATATTCGTTTTCATGATTTAAGTAATAATAGCTACAACGCAATGATTACTATGATGGTTAATGGT
TATCGTAGTTACTTAGGGCATATCCATGCAGGTGATAAACCTGAAATCGTACTGAAAGCATTTAGCCAAATTCAATTATT
ATGTGCGATGCGCGAAGGGGATTTTGGTGTGGTTGGATTAAATCAACGTATTGAAAAAGCGTTGAAAAAGTCTGATTTAA
TCCCTCATGGTGATGAAATTTGGTATTCGGGTCGTCCTGTTATGGTTACGCAAAATGATTATGGTGTTGGTTTGTATAAT
GGCGATATTGGTATTGCTATGCCAGATCCTATTGATCAGCGTTTGCGTGTCTATTTTGATATGCCAGATGGCTCTATTCG
TGGTGTGCTACCAAGCCAATTACCAGAACATGAAACGGTTTATGCTATGACCATTCATAAGTCTCAGGGCTCTGAGTTTG
AGCATACAGTATTGGCATTACCAGCAGAGTTTAGCCCAATTTTAACCCGTGAGCTGATTTATACGGGCGTGACTCGAGCG
AAGAAAAAACTCGATTTATTTGCGACGGAAAAAGTGGTGGCTCGAGGGGTTATGATTAAAACTCAGAGAAACAGTGGGTT
AGTATCACTAATGAATTAA

Upstream 100 bases:

>100_bases
CATGAAGGGCATAATGCAAATTCTAACGGTGTATTTTATTCAAAACCGAGTAAAGCCTTGTTAGAAGAGTTAGAGAAATT
GGTAGATGGAGAAACAGTTG

Downstream 100 bases:

>100_bases
ATAATATAAGAGTGATTAACTTTTAGAAGTCGGTCACTCTATTATTTCATCTTTGTAATAGTTATTTACTATTTTTGAGT
CTAGCCAAAGAGTCAAAAAT

Product: exonuclease V (RecBCD complex), alpha subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MLKQLQHLMDHGVLRPLDLQFAKFIAQQEKNSDSNLLMLLSAITSHELGRGHVCIDIEQIEQGELFTLPAKYRDALLELV
PERSAWAEQLINASTVSNGTEATPLAFDGTRLYLQRYWAFEQRVSNRITKAAQSVAVNPQLSNTLDELFARQYHFLFSAL
KKLENNNQVSRQQLVCDMLDVVQSDDLDWQAIDTVLLAATKSSELETLDQLIPNNHCVNWQKVAAAVALTRRFSVISGGP
GTGKTTTVTKLLASLVTQAKQDNKNIAIKLVAPTGKAAARLTESIGQAVQSIGLAPEVKEAIPTDASTLHRLLGYIPNQV
DFRHNKSNPLHLDVLVVDEASMVDLPMMARLLDAVPEHARVILLGDKDQLASVEAGAVLGDICQFTKMGYSQNQAQQLSQ
LTGFNLSAQLHNNAVADSLCMLQKSYRFDARSGIGQLAKAINEGSKFKVEAVWDKGFSDIRFHDLSNNSYNAMITMMVNG
YRSYLGHIHAGDKPEIVLKAFSQIQLLCAMREGDFGVVGLNQRIEKALKKSDLIPHGDEIWYSGRPVMVTQNDYGVGLYN
GDIGIAMPDPIDQRLRVYFDMPDGSIRGVLPSQLPEHETVYAMTIHKSQGSEFEHTVLALPAEFSPILTRELIYTGVTRA
KKKLDLFATEKVVARGVMIKTQRNSGLVSLMN

Sequences:

>Translated_672_residues
MLKQLQHLMDHGVLRPLDLQFAKFIAQQEKNSDSNLLMLLSAITSHELGRGHVCIDIEQIEQGELFTLPAKYRDALLELV
PERSAWAEQLINASTVSNGTEATPLAFDGTRLYLQRYWAFEQRVSNRITKAAQSVAVNPQLSNTLDELFARQYHFLFSAL
KKLENNNQVSRQQLVCDMLDVVQSDDLDWQAIDTVLLAATKSSELETLDQLIPNNHCVNWQKVAAAVALTRRFSVISGGP
GTGKTTTVTKLLASLVTQAKQDNKNIAIKLVAPTGKAAARLTESIGQAVQSIGLAPEVKEAIPTDASTLHRLLGYIPNQV
DFRHNKSNPLHLDVLVVDEASMVDLPMMARLLDAVPEHARVILLGDKDQLASVEAGAVLGDICQFTKMGYSQNQAQQLSQ
LTGFNLSAQLHNNAVADSLCMLQKSYRFDARSGIGQLAKAINEGSKFKVEAVWDKGFSDIRFHDLSNNSYNAMITMMVNG
YRSYLGHIHAGDKPEIVLKAFSQIQLLCAMREGDFGVVGLNQRIEKALKKSDLIPHGDEIWYSGRPVMVTQNDYGVGLYN
GDIGIAMPDPIDQRLRVYFDMPDGSIRGVLPSQLPEHETVYAMTIHKSQGSEFEHTVLALPAEFSPILTRELIYTGVTRA
KKKLDLFATEKVVARGVMIKTQRNSGLVSLMN
>Mature_672_residues
MLKQLQHLMDHGVLRPLDLQFAKFIAQQEKNSDSNLLMLLSAITSHELGRGHVCIDIEQIEQGELFTLPAKYRDALLELV
PERSAWAEQLINASTVSNGTEATPLAFDGTRLYLQRYWAFEQRVSNRITKAAQSVAVNPQLSNTLDELFARQYHFLFSAL
KKLENNNQVSRQQLVCDMLDVVQSDDLDWQAIDTVLLAATKSSELETLDQLIPNNHCVNWQKVAAAVALTRRFSVISGGP
GTGKTTTVTKLLASLVTQAKQDNKNIAIKLVAPTGKAAARLTESIGQAVQSIGLAPEVKEAIPTDASTLHRLLGYIPNQV
DFRHNKSNPLHLDVLVVDEASMVDLPMMARLLDAVPEHARVILLGDKDQLASVEAGAVLGDICQFTKMGYSQNQAQQLSQ
LTGFNLSAQLHNNAVADSLCMLQKSYRFDARSGIGQLAKAINEGSKFKVEAVWDKGFSDIRFHDLSNNSYNAMITMMVNG
YRSYLGHIHAGDKPEIVLKAFSQIQLLCAMREGDFGVVGLNQRIEKALKKSDLIPHGDEIWYSGRPVMVTQNDYGVGLYN
GDIGIAMPDPIDQRLRVYFDMPDGSIRGVLPSQLPEHETVYAMTIHKSQGSEFEHTVLALPAEFSPILTRELIYTGVTRA
KKKLDLFATEKVVARGVMIKTQRNSGLVSLMN

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=676, Percent_Identity=46.8934911242604, Blast_Score=553, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 74377; Mature: 74377

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQLQHLMDHGVLRPLDLQFAKFIAQQEKNSDSNLLMLLSAITSHELGRGHVCIDIEQI
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEHHCC
EQGELFTLPAKYRDALLELVPERSAWAEQLINASTVSNGTEATPLAFDGTRLYLQRYWAF
CCCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHH
EQRVSNRITKAAQSVAVNPQLSNTLDELFARQYHFLFSALKKLENNNQVSRQQLVCDMLD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VVQSDDLDWQAIDTVLLAATKSSELETLDQLIPNNHCVNWQKVAAAVALTRRFSVISGGP
HHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCC
GTGKTTTVTKLLASLVTQAKQDNKNIAIKLVAPTGKAAARLTESIGQAVQSIGLAPEVKE
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHH
AIPTDASTLHRLLGYIPNQVDFRHNKSNPLHLDVLVVDEASMVDLPMMARLLDAVPEHAR
HCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCE
VILLGDKDQLASVEAGAVLGDICQFTKMGYSQNQAQQLSQLTGFNLSAQLHNNAVADSLC
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEHHCCCHHHHHHH
MLQKSYRFDARSGIGQLAKAINEGSKFKVEAVWDKGFSDIRFHDLSNNSYNAMITMMVNG
HHHHHCCCCHHCCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEEEHHH
YRSYLGHIHAGDKPEIVLKAFSQIQLLCAMREGDFGVVGLNQRIEKALKKSDLIPHGDEI
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCE
WYSGRPVMVTQNDYGVGLYNGDIGIAMPDPIDQRLRVYFDMPDGSIRGVLPSQLPEHETV
EECCCEEEEECCCCEEEEEECCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEE
YAMTIHKSQGSEFEHTVLALPAEFSPILTRELIYTGVTRAKKKLDLFATEKVVARGVMIK
EEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
TQRNSGLVSLMN
EECCCCCEEECC
>Mature Secondary Structure
MLKQLQHLMDHGVLRPLDLQFAKFIAQQEKNSDSNLLMLLSAITSHELGRGHVCIDIEQI
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEHHCC
EQGELFTLPAKYRDALLELVPERSAWAEQLINASTVSNGTEATPLAFDGTRLYLQRYWAF
CCCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHH
EQRVSNRITKAAQSVAVNPQLSNTLDELFARQYHFLFSALKKLENNNQVSRQQLVCDMLD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VVQSDDLDWQAIDTVLLAATKSSELETLDQLIPNNHCVNWQKVAAAVALTRRFSVISGGP
HHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCC
GTGKTTTVTKLLASLVTQAKQDNKNIAIKLVAPTGKAAARLTESIGQAVQSIGLAPEVKE
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHH
AIPTDASTLHRLLGYIPNQVDFRHNKSNPLHLDVLVVDEASMVDLPMMARLLDAVPEHAR
HCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCE
VILLGDKDQLASVEAGAVLGDICQFTKMGYSQNQAQQLSQLTGFNLSAQLHNNAVADSLC
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEHHCCCHHHHHHH
MLQKSYRFDARSGIGQLAKAINEGSKFKVEAVWDKGFSDIRFHDLSNNSYNAMITMMVNG
HHHHHCCCCHHCCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEEEHHH
YRSYLGHIHAGDKPEIVLKAFSQIQLLCAMREGDFGVVGLNQRIEKALKKSDLIPHGDEI
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCE
WYSGRPVMVTQNDYGVGLYNGDIGIAMPDPIDQRLRVYFDMPDGSIRGVLPSQLPEHETV
EECCCEEEEECCCCEEEEEECCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEE
YAMTIHKSQGSEFEHTVLALPAEFSPILTRELIYTGVTRAKKKLDLFATEKVVARGVMIK
EEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
TQRNSGLVSLMN
EECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]