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The map label for this gene is nahR [H]

Identifier: 59711181

GI number: 59711181

Start: 627309

End: 628301

Strand: Direct

Name: nahR [H]

Synonym: VF_0574

Alternate gene names: 59711181

Gene position: 627309-628301 (Clockwise)

Preceding gene: 59711179

Following gene: 59711185

Centisome position: 21.65

GC content: 35.45

Gene sequence:

>993_bases
ATGAGTTCAAGATTACGAGTTACTATAAAATTATTCAAATCGATTGTATTGCTATTAACTATGAATGAAATTAATTGGAA
GGCAGTAGACTTAAATTTATTAGTCGCTTTTAGCACTTTAATGGAAACCAAAAGTGTTTCACTCGCTGCAAATAAATTGT
TTGTGGGTCAATCAGCGATGAGTCATAGTCTTTCTCGTCTGCGTGAGTTACTACATGATCCTTTGTTTGAAAGACAAGGA
CATCAAATGATCCCCACAGCAAAAGCGATTCAATTATATCCTTTAGTTAATAAAGTATTACAAACGATCTCTGGTGATAT
TTTAAAGGTGGATACGTTTGAAGCGAGTGAGTTTACCGGTACTTTTAAAATAGGGATGACGGATTATGCAGAACTTCTTT
TTGCAGCAGATATTTTTGATGCCATTCATCAATTAGCGCCAAATGCGCAACTTTGTTTTACTACGGTAGATAAAGCTAAC
TATCAAGATCGTTTTGATTCTGAACCATTAGATCTTGTTATTGGAAGCATGAAACCAGAATTAAAAGAATTTCAATATCA
GACGTTATACACAGAAAAGCACGTATGTATGTGGGATGGACAGCGACATTTGTTTAGTTCGCCAATAACTCTTGACGATT
ATATTTCTTTGCCCCACGCATTAGTCAGCCCTGATGGAGCATTAAAAACAGGGGTAGATAAAGAGTTAAAAGCATTAGGA
GTGGGTCGTTCTGTTAGTGTGGCCTCTAAGCATTTTTTAACCATAAGACATTTAATGAAAAAAAGAGATTTAATTTGTGT
GGTTCCTGAGTTGATGGCTCAGTTAGATCTTTTTTCTGAAAAACTGGTGCATTCCGAGCCACCAATTAATGTTGGGGAAT
TTGATATTCAATTGATTTGGCAGACGAGAAATAAAGAAAATAAACGCTATCAATGGCTTAAAGAGTTACTTATTCAAACC
ATTGAGAAAAGCGTTGCAGTTTATAGGGCGTAG

Upstream 100 bases:

>100_bases
ACCAAAACTTACCCAGCCTAACAAAAAAAATCGTTTAAATATTTCAAACATAATCTACTCAGCTTTTGATGTGTGATCCA
ATTTTGGATATTCAATTTTG

Downstream 100 bases:

>100_bases
TATGAGTTTTTCTAATTTCTATCGCCCAAAAGCGTCTTTAATTTTTTCATCTGTTTTATATTGGCTTAGTGCATAAACAG
ACCAAATAGCAGCAGGGATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSSRLRVTIKLFKSIVLLLTMNEINWKAVDLNLLVAFSTLMETKSVSLAANKLFVGQSAMSHSLSRLRELLHDPLFERQG
HQMIPTAKAIQLYPLVNKVLQTISGDILKVDTFEASEFTGTFKIGMTDYAELLFAADIFDAIHQLAPNAQLCFTTVDKAN
YQDRFDSEPLDLVIGSMKPELKEFQYQTLYTEKHVCMWDGQRHLFSSPITLDDYISLPHALVSPDGALKTGVDKELKALG
VGRSVSVASKHFLTIRHLMKKRDLICVVPELMAQLDLFSEKLVHSEPPINVGEFDIQLIWQTRNKENKRYQWLKELLIQT
IEKSVAVYRA

Sequences:

>Translated_330_residues
MSSRLRVTIKLFKSIVLLLTMNEINWKAVDLNLLVAFSTLMETKSVSLAANKLFVGQSAMSHSLSRLRELLHDPLFERQG
HQMIPTAKAIQLYPLVNKVLQTISGDILKVDTFEASEFTGTFKIGMTDYAELLFAADIFDAIHQLAPNAQLCFTTVDKAN
YQDRFDSEPLDLVIGSMKPELKEFQYQTLYTEKHVCMWDGQRHLFSSPITLDDYISLPHALVSPDGALKTGVDKELKALG
VGRSVSVASKHFLTIRHLMKKRDLICVVPELMAQLDLFSEKLVHSEPPINVGEFDIQLIWQTRNKENKRYQWLKELLIQT
IEKSVAVYRA
>Mature_329_residues
SSRLRVTIKLFKSIVLLLTMNEINWKAVDLNLLVAFSTLMETKSVSLAANKLFVGQSAMSHSLSRLRELLHDPLFERQGH
QMIPTAKAIQLYPLVNKVLQTISGDILKVDTFEASEFTGTFKIGMTDYAELLFAADIFDAIHQLAPNAQLCFTTVDKANY
QDRFDSEPLDLVIGSMKPELKEFQYQTLYTEKHVCMWDGQRHLFSSPITLDDYISLPHALVSPDGALKTGVDKELKALGV
GRSVSVASKHFLTIRHLMKKRDLICVVPELMAQLDLFSEKLVHSEPPINVGEFDIQLIWQTRNKENKRYQWLKELLIQTI
EKSVAVYRA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=305, Percent_Identity=24.2622950819672, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87081766, Length=243, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786820, Length=274, Percent_Identity=25.5474452554745, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37527; Mature: 37396

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRLRVTIKLFKSIVLLLTMNEINWKAVDLNLLVAFSTLMETKSVSLAANKLFVGQSAM
CCCCCEEHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEECHHHH
SHSLSRLRELLHDPLFERQGHQMIPTAKAIQLYPLVNKVLQTISGDILKVDTFEASEFTG
HHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCE
TFKIGMTDYAELLFAADIFDAIHQLAPNAQLCFTTVDKANYQDRFDSEPLDLVIGSMKPE
EEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHEECCCCHH
LKEFQYQTLYTEKHVCMWDGQRHLFSSPITLDDYISLPHALVSPDGALKTGVDKELKALG
HHHHHHHHHHCCCEEEEECCCHHHCCCCCCHHHHHCCCHHHCCCCCCHHCCCHHHHHHHC
VGRSVSVASKHFLTIRHLMKKRDLICVVPELMAQLDLFSEKLVHSEPPINVGEFDIQLIW
CCCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
QTRNKENKRYQWLKELLIQTIEKSVAVYRA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSRLRVTIKLFKSIVLLLTMNEINWKAVDLNLLVAFSTLMETKSVSLAANKLFVGQSAM
CCCCEEHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEECHHHH
SHSLSRLRELLHDPLFERQGHQMIPTAKAIQLYPLVNKVLQTISGDILKVDTFEASEFTG
HHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCE
TFKIGMTDYAELLFAADIFDAIHQLAPNAQLCFTTVDKANYQDRFDSEPLDLVIGSMKPE
EEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHEECCCCHH
LKEFQYQTLYTEKHVCMWDGQRHLFSSPITLDDYISLPHALVSPDGALKTGVDKELKALG
HHHHHHHHHHCCCEEEEECCCHHHCCCCCCHHHHHCCCHHHCCCCCCHHCCCHHHHHHHC
VGRSVSVASKHFLTIRHLMKKRDLICVVPELMAQLDLFSEKLVHSEPPINVGEFDIQLIW
CCCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
QTRNKENKRYQWLKELLIQTIEKSVAVYRA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]