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The map label for this gene is luxS [H]

Identifier: 59711152

GI number: 59711152

Start: 593925

End: 594443

Strand: Direct

Name: luxS [H]

Synonym: VF_0545

Alternate gene names: 59711152

Gene position: 593925-594443 (Clockwise)

Preceding gene: 59711151

Following gene: 59711155

Centisome position: 20.5

GC content: 38.92

Gene sequence:

>519_bases
ATGCCATTGTTAGATAGTTTTACTGTAGATCATACTCGTATGGAAGCACCGGCGGTTCGTGTTGCGAAAACAATGCAAAC
ACCTAAAGGCGATACAATTACTGTATTTGATTTACGCTTTACGGCACCAAATAAAGATATTCTGTCAGAGAAAGGCATTC
ATACATTAGAGCATTTATACGCAGGTTTTATGCGTAACCACCTTAATGGCAGCGGTGTTGAAATTATTGATATCTCGCCA
ATGGGGTGTCGTACTGGCTTCTATATGAGCTTGATCGGTACACCAGCTGAGCAAGCGGTTGCTGATGCATGGGTTTCATC
AATGGAAGATGTGCTGAAAGTAGAAGCTCAAAATAAAATTCCTGAACTGAATGAGTATCAATGTGGTACTTATGAAATGC
ATTCACTTGATGAAGCAAAAGCAATCGCAAGCACAGTGCTTGCATCAGGTATCAGCGTAAATAAAAATGATGAACTTGCA
CTATCTGATTCAATGCTAAAAGAATTATCTAATCATTAA

Upstream 100 bases:

>100_bases
AAAACTTATGGTTGGCAATTAAAGCAATGTAAGGCTGAGCTAGAGAGACAAAGCAGTTGGTGGTGGTAAGCCATCATTTA
TAACTTTAAAGGATTAAAAT

Downstream 100 bases:

>100_bases
TTGACGTTTTAATTTGAAAAAAAAGCCCGCATTTAGCGGGCTTTTTTTAGCTGAATATCAGCTTTAACCATTGATAGTAT
TGGTATACAAATTATTTATC

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPLLDSFTVDHTRMEAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGFMRNHLNGSGVEIIDISP
MGCRTGFYMSLIGTPAEQAVADAWVSSMEDVLKVEAQNKIPELNEYQCGTYEMHSLDEAKAIASTVLASGISVNKNDELA
LSDSMLKELSNH

Sequences:

>Translated_172_residues
MPLLDSFTVDHTRMEAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGFMRNHLNGSGVEIIDISP
MGCRTGFYMSLIGTPAEQAVADAWVSSMEDVLKVEAQNKIPELNEYQCGTYEMHSLDEAKAIASTVLASGISVNKNDELA
LSDSMLKELSNH
>Mature_171_residues
PLLDSFTVDHTRMEAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGFMRNHLNGSGVEIIDISPM
GCRTGFYMSLIGTPAEQAVADAWVSSMEDVLKVEAQNKIPELNEYQCGTYEMHSLDEAKAIASTVLASGISVNKNDELAL
SDSMLKELSNH

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=169, Percent_Identity=75.7396449704142, Blast_Score=281, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 18889; Mature: 18757

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMEAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLY
CCCCCCCCCCHHHHHCHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRNHLNGSGVEIIDISPMGCRTGFYMSLIGTPAEQAVADAWVSSMEDVLKVEAQNKI
HHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PELNEYQCGTYEMHSLDEAKAIASTVLASGISVNKNDELALSDSMLKELSNH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCC
>Mature Secondary Structure 
PLLDSFTVDHTRMEAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLY
CCCCCCCCCHHHHHCHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRNHLNGSGVEIIDISPMGCRTGFYMSLIGTPAEQAVADAWVSSMEDVLKVEAQNKI
HHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PELNEYQCGTYEMHSLDEAKAIASTVLASGISVNKNDELALSDSMLKELSNH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA