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The map label for this gene is xerD [H]

Identifier: 59711055

GI number: 59711055

Start: 477430

End: 478326

Strand: Direct

Name: xerD [H]

Synonym: VF_0448

Alternate gene names: 59711055

Gene position: 477430-478326 (Clockwise)

Preceding gene: 59711053

Following gene: 59711056

Centisome position: 16.48

GC content: 39.13

Gene sequence:

>897_bases
ATGAATAATGATATGGCATTAATGGAGCGTTTTTTAGATACCATGTGGATGGAGCGTGGCCTGTCTGAAAATACGTTGGC
TTCATATCGAAACGATTTAGTGAAGTTGTTGCAGTGGTTAGAAGATAATCACTATAAATGTGCTTCTATTTCAGCGATGG
GACTTAATGAGTTTCAAGCTTATTTAGTTGATAAAGAATATAAACAAACTTCTCGAGCTCGAATGCTGTCTGCATTACGT
CGTTTTTTTCAGTATTTACATCGTGAAAAAATCCGCGGAGATGATCCCACAGCATTACTTGCTAGCCCTAAATTACCTCA
ACGCTTACCAAAAGATTTAAGTGAAGAGCAAGTTGATGCGTTGCTTAATGCTCCGAATGTCGAAGATCCTCTAGAGCTTC
GAGATCGAGCAATGTTAGAACTACTTTATGCAACAGGTTTACGTGTTACTGAGCTAGTTAGCTTAACCATGGAAAATGTA
AGTTTACGCCAAGGTGTTGTACGAGTTACTGGTAAAGGTGATAAAGAACGTTTAGTCCCAATGGGAGAGAATGCCGTAGA
TTGGATTGAGCAGTTTTTAACTCATGGTCGTCCAATGCTGCTTGGTGAAAAAAGTTCGGATGTCGTGTTTCCTAGTAAAC
GAGCAAAACAAATGACTCGTCAGACATTTTGGCACCGAATTAAGCATTATGCTGTTATTGCTGGTATTGATTCTGATAAA
TTATCGCCACACGTATTGCGACATGCTTTTGCTACACATCTTTTAAACTATGGCGCAGATCTCCGTGTTGTACAAATGTT
GTTAGGACATAGTGATCTTTCAACAACACAAATATATACTCATGTAGCAACGGAACGTTTGAAGCAAATTCATCAAGAGC
ATCACCCTCGCTCATAA

Upstream 100 bases:

>100_bases
AATGATTATTAAAATTAAACTTGCATTTAAAGTGGGTAAAATTGTTTAATACTGTAATTCTAACCAGTGTTTTCTGGAAT
GTACGTTAAGTGGTAAGTAG

Downstream 100 bases:

>100_bases
TTGAGGGAACTTCTGGTGGTTTAAAAACTCTAAACTTCAAATCTTCTACAATTACATTTTTTATAGGTACCCTTATGTCA
TTTATTCGCCGAACTAGTGC

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNNDMALMERFLDTMWMERGLSENTLASYRNDLVKLLQWLEDNHYKCASISAMGLNEFQAYLVDKEYKQTSRARMLSALR
RFFQYLHREKIRGDDPTALLASPKLPQRLPKDLSEEQVDALLNAPNVEDPLELRDRAMLELLYATGLRVTELVSLTMENV
SLRQGVVRVTGKGDKERLVPMGENAVDWIEQFLTHGRPMLLGEKSSDVVFPSKRAKQMTRQTFWHRIKHYAVIAGIDSDK
LSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS

Sequences:

>Translated_298_residues
MNNDMALMERFLDTMWMERGLSENTLASYRNDLVKLLQWLEDNHYKCASISAMGLNEFQAYLVDKEYKQTSRARMLSALR
RFFQYLHREKIRGDDPTALLASPKLPQRLPKDLSEEQVDALLNAPNVEDPLELRDRAMLELLYATGLRVTELVSLTMENV
SLRQGVVRVTGKGDKERLVPMGENAVDWIEQFLTHGRPMLLGEKSSDVVFPSKRAKQMTRQTFWHRIKHYAVIAGIDSDK
LSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS
>Mature_298_residues
MNNDMALMERFLDTMWMERGLSENTLASYRNDLVKLLQWLEDNHYKCASISAMGLNEFQAYLVDKEYKQTSRARMLSALR
RFFQYLHREKIRGDDPTALLASPKLPQRLPKDLSEEQVDALLNAPNVEDPLELRDRAMLELLYATGLRVTELVSLTMENV
SLRQGVVRVTGKGDKERLVPMGENAVDWIEQFLTHGRPMLLGEKSSDVVFPSKRAKQMTRQTFWHRIKHYAVIAGIDSDK
LSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=301, Percent_Identity=68.7707641196013, Blast_Score=430, Evalue=1e-122,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=38.013698630137, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1790768, Length=169, Percent_Identity=28.4023668639053, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790767, Length=179, Percent_Identity=27.3743016759777, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34404; Mature: 34404

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNDMALMERFLDTMWMERGLSENTLASYRNDLVKLLQWLEDNHYKCASISAMGLNEFQA
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
YLVDKEYKQTSRARMLSALRRFFQYLHREKIRGDDPTALLASPKLPQRLPKDLSEEQVDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHCCHHHHHH
LLNAPNVEDPLELRDRAMLELLYATGLRVTELVSLTMENVSLRQGVVRVTGKGDKERLVP
HHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCC
MGENAVDWIEQFLTHGRPMLLGEKSSDVVFPSKRAKQMTRQTFWHRIKHYAVIAGIDSDK
CCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCC
LSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNNDMALMERFLDTMWMERGLSENTLASYRNDLVKLLQWLEDNHYKCASISAMGLNEFQA
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
YLVDKEYKQTSRARMLSALRRFFQYLHREKIRGDDPTALLASPKLPQRLPKDLSEEQVDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHCCHHHHHH
LLNAPNVEDPLELRDRAMLELLYATGLRVTELVSLTMENVSLRQGVVRVTGKGDKERLVP
HHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCC
MGENAVDWIEQFLTHGRPMLLGEKSSDVVFPSKRAKQMTRQTFWHRIKHYAVIAGIDSDK
CCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCC
LSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA