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The map label for this gene is rng [H]

Identifier: 59710983

GI number: 59710983

Start: 407563

End: 409032

Strand: Direct

Name: rng [H]

Synonym: VF_0376

Alternate gene names: 59710983

Gene position: 407563-409032 (Clockwise)

Preceding gene: 59710982

Following gene: 59710984

Centisome position: 14.07

GC content: 39.8

Gene sequence:

>1470_bases
ATGAGTACAGAGTTGTTAATAAACGTAACCCCGAGTGAAACTCGAGTTGCGATGATTGAAGCCGGTGTGCTTCAAGAAGT
TCACGTTGAAAGAGAAGCAAGGCGCGGTATTGTTGGTAATATTTATAAAGGCCGTGTAAGCCGAGTATTACCGGGGATGC
AAGCTGCGTTTATTGATATCGGTTTGGATAAAGCCGCATTTCTTCACGCCTCAGATATTGTCCCTCATACTGAATGTGTT
TCTGAAAATGAAAAACGTCAATTCCAAGTAAGGGATATTTCACAGCTTGTCCACCAAGGGCAAGATCTCGTTGTACAAGT
AGTCAAAGATCCTCTTGGTACAAAAGGTGCTCGCTTGACAACCGATATTACTCTGCCTTCTCGTTACTTGGTGTTTATGC
CTGGGGCAAGTCATGTTGGTGTATCTCAACGCATTGAAAGCGAGAAAGAGCGTAATCGTTTAAAAGATACCGTCTCTGAT
TATTGTGATGAGTTTGGTGGTTTTATTATTCGAACCGCAGCTGAAGGAGCGAGTGAAGCTGAGATCTCACAAGATGCCGC
TTTCTTAAAACGTTTATGGCATAAAGTAATTGAACGTCGTAAAAAGAACAAAACAAAGTCAATGCTTTATGGTGAGTTAG
GTTTAGACCAACGCATTTTACGTGATTTTGTGGGCACAGAGCTTGATCTGATTCGTGTGGATTCAAAGCTAGCATTTGAG
AAGCTAAAAGAATTTACAACAGAATTCGTACCTGAATTAACAAAGAAATTGGAATATTACTCAGGTGATAAACCTATTTT
TGACATGTATGAAACTGAGAATGAAATTCAACGAGCACTTGATCGTAAAGTAGAATTAAAATCTGGCGGTTATCTGATTA
TCGATCAAACCGAAGCTATGACTACCGTGGACATAAATACCGGTGCTTTTGTTGGTCGACGCAATTTAGAAGAAACCATT
TTTAATACCAATATTGAAGCTACACAAGCGATAGCTCGTCAACTTCGCTTACGGAATTTAGGTGGGATCATCATTATTGA
TTTCATTGATATGCTAAGTGAAGAGCATCGACGTCGCGTTCTCCAGTCTTTAGGCTCTGCTTTAGAAAAAGATCGTGTAA
AAACCAACATCAATGGTTTTACACAACTTGGTTTAGTTGAGATGACTCGTAAACGAACTCGAGAAAGTATTGAACATATA
TTATGTGGTCAATGTCCTACTTGTGAAGGTCGTGGAGCGGTGAAAACAGTGGAGAGCGTATGTTACGAAATTTTACGTGA
AATCACGCGTGTAAATCGTGCGTACGACTCTGATAAGTTTGTTGTTTATGCATCTGTAGCTGTTGCTGATGCCCTTGAAG
GGGAAGAGTCTCATGCATTAGCTGAACTTGAACTCTTTATTGGTAAACAAGTTAAAATTCAAGCTGAACCTCTTTATATC
CAAGAGCAGTTTGACGTCGTTATGATGTAA

Upstream 100 bases:

>100_bases
CTCGCGTATTGATGGCAGCTATCACGCTGTCATGGGACTGCCTTTGATGGAAACAGATCAGCTCTTACACCAATTTTTGT
AAAATTAGTGAGGTGCTCCA

Downstream 100 bases:

>100_bases
GAGAAAAATAAGTGACCACTAAGTTAATTCGTTTTGAACGTTGCTTGATGGGATTATTGCTGCTGGTATTTTTACTAGCA
GCATTAGTCATTACCAGCCT

Product: ribonuclease G

Products: NA

Alternate protein names: RNase G; Cytoplasmic axial filament protein [H]

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSTELLINVTPSETRVAMIEAGVLQEVHVEREARRGIVGNIYKGRVSRVLPGMQAAFIDIGLDKAAFLHASDIVPHTECV
SENEKRQFQVRDISQLVHQGQDLVVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESEKERNRLKDTVSD
YCDEFGGFIIRTAAEGASEAEISQDAAFLKRLWHKVIERRKKNKTKSMLYGELGLDQRILRDFVGTELDLIRVDSKLAFE
KLKEFTTEFVPELTKKLEYYSGDKPIFDMYETENEIQRALDRKVELKSGGYLIIDQTEAMTTVDINTGAFVGRRNLEETI
FNTNIEATQAIARQLRLRNLGGIIIIDFIDMLSEEHRRRVLQSLGSALEKDRVKTNINGFTQLGLVEMTRKRTRESIEHI
LCGQCPTCEGRGAVKTVESVCYEILREITRVNRAYDSDKFVVYASVAVADALEGEESHALAELELFIGKQVKIQAEPLYI
QEQFDVVMM

Sequences:

>Translated_489_residues
MSTELLINVTPSETRVAMIEAGVLQEVHVEREARRGIVGNIYKGRVSRVLPGMQAAFIDIGLDKAAFLHASDIVPHTECV
SENEKRQFQVRDISQLVHQGQDLVVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESEKERNRLKDTVSD
YCDEFGGFIIRTAAEGASEAEISQDAAFLKRLWHKVIERRKKNKTKSMLYGELGLDQRILRDFVGTELDLIRVDSKLAFE
KLKEFTTEFVPELTKKLEYYSGDKPIFDMYETENEIQRALDRKVELKSGGYLIIDQTEAMTTVDINTGAFVGRRNLEETI
FNTNIEATQAIARQLRLRNLGGIIIIDFIDMLSEEHRRRVLQSLGSALEKDRVKTNINGFTQLGLVEMTRKRTRESIEHI
LCGQCPTCEGRGAVKTVESVCYEILREITRVNRAYDSDKFVVYASVAVADALEGEESHALAELELFIGKQVKIQAEPLYI
QEQFDVVMM
>Mature_488_residues
STELLINVTPSETRVAMIEAGVLQEVHVEREARRGIVGNIYKGRVSRVLPGMQAAFIDIGLDKAAFLHASDIVPHTECVS
ENEKRQFQVRDISQLVHQGQDLVVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESEKERNRLKDTVSDY
CDEFGGFIIRTAAEGASEAEISQDAAFLKRLWHKVIERRKKNKTKSMLYGELGLDQRILRDFVGTELDLIRVDSKLAFEK
LKEFTTEFVPELTKKLEYYSGDKPIFDMYETENEIQRALDRKVELKSGGYLIIDQTEAMTTVDINTGAFVGRRNLEETIF
NTNIEATQAIARQLRLRNLGGIIIIDFIDMLSEEHRRRVLQSLGSALEKDRVKTNINGFTQLGLVEMTRKRTRESIEHIL
CGQCPTCEGRGAVKTVESVCYEILREITRVNRAYDSDKFVVYASVAVADALEGEESHALAELELFIGKQVKIQAEPLYIQ
EQFDVVMM

Specific function: Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure [H]

COG id: COG1530

COG function: function code J; Ribonucleases G and E

Gene ontology:

Cell location: Cytoplasm, cytoskeleton [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI87082235, Length=489, Percent_Identity=78.5276073619632, Blast_Score=792, Evalue=0.0,
Organism=Escherichia coli, GI1787325, Length=464, Percent_Identity=33.6206896551724, Blast_Score=264, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR019307
- InterPro:   IPR022967
- InterPro:   IPR004659 [H]

Pfam domain/function: PF10150 RNase_E_G; PF00575 S1 [H]

EC number: 3.1.4.- [C]

Molecular weight: Translated: 55326; Mature: 55195

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTELLINVTPSETRVAMIEAGVLQEVHVEREARRGIVGNIYKGRVSRVLPGMQAAFIDI
CCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHEEC
GLDKAAFLHASDIVPHTECVSENEKRQFQVRDISQLVHQGQDLVVQVVKDPLGTKGARLT
CCCHHHHEEHHCCCCCHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEE
TDITLPSRYLVFMPGASHVGVSQRIESEKERNRLKDTVSDYCDEFGGFIIRTAAEGASEA
EEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHH
EISQDAAFLKRLWHKVIERRKKNKTKSMLYGELGLDQRILRDFVGTELDLIRVDSKLAFE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECHHHHHH
KLKEFTTEFVPELTKKLEYYSGDKPIFDMYETENEIQRALDRKVELKSGGYLIIDQTEAM
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHCEEECCCCEEEEECCCCE
TTVDINTGAFVGRRNLEETIFNTNIEATQAIARQLRLRNLGGIIIIDFIDMLSEEHRRRV
EEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
LQSLGSALEKDRVKTNINGFTQLGLVEMTRKRTRESIEHILCGQCPTCEGRGAVKTVESV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
CYEILREITRVNRAYDSDKFVVYASVAVADALEGEESHALAELELFIGKQVKIQAEPLYI
HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCEEE
QEQFDVVMM
ECCCCEEEC
>Mature Secondary Structure 
STELLINVTPSETRVAMIEAGVLQEVHVEREARRGIVGNIYKGRVSRVLPGMQAAFIDI
CCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHEEC
GLDKAAFLHASDIVPHTECVSENEKRQFQVRDISQLVHQGQDLVVQVVKDPLGTKGARLT
CCCHHHHEEHHCCCCCHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEE
TDITLPSRYLVFMPGASHVGVSQRIESEKERNRLKDTVSDYCDEFGGFIIRTAAEGASEA
EEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHH
EISQDAAFLKRLWHKVIERRKKNKTKSMLYGELGLDQRILRDFVGTELDLIRVDSKLAFE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECHHHHHH
KLKEFTTEFVPELTKKLEYYSGDKPIFDMYETENEIQRALDRKVELKSGGYLIIDQTEAM
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHCEEECCCCEEEEECCCCE
TTVDINTGAFVGRRNLEETIFNTNIEATQAIARQLRLRNLGGIIIIDFIDMLSEEHRRRV
EEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
LQSLGSALEKDRVKTNINGFTQLGLVEMTRKRTRESIEHILCGQCPTCEGRGAVKTVESV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
CYEILREITRVNRAYDSDKFVVYASVAVADALEGEESHALAELELFIGKQVKIQAEPLYI
HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCEEE
QEQFDVVMM
ECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]