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The map label for this gene is cysC [H]

Identifier: 59710930

GI number: 59710930

Start: 333649

End: 334263

Strand: Direct

Name: cysC [H]

Synonym: VF_0323

Alternate gene names: 59710930

Gene position: 333649-334263 (Clockwise)

Preceding gene: 59710929

Following gene: 172087655

Centisome position: 11.51

GC content: 40.0

Gene sequence:

>615_bases
ATGACAGCACTATCAGTAATAAAAGATGAGAATGTCGTTTGGCATCAGCATACAGTAACAAAGGAAATTCGTTCCGATCT
TAAAAAACAAAAACCGGCGGTGCTTTGGTTTACTGGATTATCGGGGGCAGGGAAATCAACCATTGCAGGTGCATTAGAAA
GTAAATTGGCAGAGCTTGGGTATCATACCTATTTACTTGATGGCGATAATGTTCGTCATGGTTTATGTAAAGATTTGGGC
TTTTCAGATCATGATAGGCAAGAAAACATTAGACGTATTGGTGAGCTTTCAAAGTTGATGGCAGATGCAGGGCTTATTGT
ATTAAGTGCGTTTATTTCACCTCATAGAGCTGAGCGTCAAATGGTTCGAGAATTACTGCCTGAGGGGGAGTTTTTAGAAG
TCTTTGTGAATACCTCTCTGGATGAGTGTGAAAAAAGAGATCCGAAGGGCTTATATAAAAAGGCACGAGCTGGTGAGATA
AAACATTTCACAGGGATTGACTCTGAATATCAACAACCGTTAAGCCCTGAAATTGATTTGCCCGCAGGAACTCAGTCGAT
AGAAGCATTAGTTGAACAGTGTTTAGAAGAGCTAAAAGTACGTTCAATTATCTAG

Upstream 100 bases:

>100_bases
TCGATTATGTGAAAGTGGGATTACCCATGTCGATTATTTATTCGGTATTGGTATTAGCATTAATCCCTTATTTTTTCCCA
TTTTAATTCAAGGATGAAAC

Downstream 100 bases:

>100_bases
AAGAAAAATAGCCCTAATAGTGATTGTTTTTGGAACTACTAGGGCTTTAATTATTTTTGATGCTTATCTATTAACTTAGA
CAACTAAGCCATCGTTGAAA

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTALSVIKDENVVWHQHTVTKEIRSDLKKQKPAVLWFTGLSGAGKSTIAGALESKLAELGYHTYLLDGDNVRHGLCKDLG
FSDHDRQENIRRIGELSKLMADAGLIVLSAFISPHRAERQMVRELLPEGEFLEVFVNTSLDECEKRDPKGLYKKARAGEI
KHFTGIDSEYQQPLSPEIDLPAGTQSIEALVEQCLEELKVRSII

Sequences:

>Translated_204_residues
MTALSVIKDENVVWHQHTVTKEIRSDLKKQKPAVLWFTGLSGAGKSTIAGALESKLAELGYHTYLLDGDNVRHGLCKDLG
FSDHDRQENIRRIGELSKLMADAGLIVLSAFISPHRAERQMVRELLPEGEFLEVFVNTSLDECEKRDPKGLYKKARAGEI
KHFTGIDSEYQQPLSPEIDLPAGTQSIEALVEQCLEELKVRSII
>Mature_203_residues
TALSVIKDENVVWHQHTVTKEIRSDLKKQKPAVLWFTGLSGAGKSTIAGALESKLAELGYHTYLLDGDNVRHGLCKDLGF
SDHDRQENIRRIGELSKLMADAGLIVLSAFISPHRAERQMVRELLPEGEFLEVFVNTSLDECEKRDPKGLYKKARAGEIK
HFTGIDSEYQQPLSPEIDLPAGTQSIEALVEQCLEELKVRSII

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=203, Percent_Identity=48.2758620689655, Blast_Score=187, Evalue=5e-48,
Organism=Homo sapiens, GI62912492, Length=206, Percent_Identity=47.5728155339806, Blast_Score=185, Evalue=3e-47,
Organism=Homo sapiens, GI34447231, Length=206, Percent_Identity=47.5728155339806, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI1789107, Length=198, Percent_Identity=65.1515151515152, Blast_Score=261, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17542422, Length=201, Percent_Identity=50.2487562189055, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6322852, Length=196, Percent_Identity=49.4897959183673, Blast_Score=186, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24667032, Length=196, Percent_Identity=46.4285714285714, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667028, Length=196, Percent_Identity=46.4285714285714, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667036, Length=196, Percent_Identity=46.4285714285714, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667040, Length=196, Percent_Identity=46.4285714285714, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI116007838, Length=196, Percent_Identity=46.4285714285714, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24667044, Length=196, Percent_Identity=46.4285714285714, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 22824; Mature: 22693

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALSVIKDENVVWHQHTVTKEIRSDLKKQKPAVLWFTGLSGAGKSTIAGALESKLAELG
CCCHHHHCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCC
YHTYLLDGDNVRHGLCKDLGFSDHDRQENIRRIGELSKLMADAGLIVLSAFISPHRAERQ
CEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
MVRELLPEGEFLEVFVNTSLDECEKRDPKGLYKKARAGEIKHFTGIDSEYQQPLSPEIDL
HHHHHCCCCCEEEHEECCCHHHHHCCCCHHHHHHHHCCCCHHHCCCCHHHHCCCCCCCCC
PAGTQSIEALVEQCLEELKVRSII
CCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TALSVIKDENVVWHQHTVTKEIRSDLKKQKPAVLWFTGLSGAGKSTIAGALESKLAELG
CCHHHHCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCC
YHTYLLDGDNVRHGLCKDLGFSDHDRQENIRRIGELSKLMADAGLIVLSAFISPHRAERQ
CEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
MVRELLPEGEFLEVFVNTSLDECEKRDPKGLYKKARAGEIKHFTGIDSEYQQPLSPEIDL
HHHHHCCCCCEEEHEECCCHHHHHCCCCHHHHHHHHCCCCHHHCCCCHHHHCCCCCCCCC
PAGTQSIEALVEQCLEELKVRSII
CCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]