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The map label for this gene is surA

Identifier: 59710895

GI number: 59710895

Start: 292201

End: 293514

Strand: Reverse

Name: surA

Synonym: VF_0288

Alternate gene names: 59710895

Gene position: 293514-292201 (Counterclockwise)

Preceding gene: 59710896

Following gene: 59710894

Centisome position: 10.13

GC content: 40.26

Gene sequence:

>1314_bases
ATGAAAAACTGGAAATTCCCACTGATTAGCACACTTTTATTGCTGCTAACCATCAATGTGCATGCTGCTCCTGTTGAGCT
TGATCGTGTTGTTGCGATCGTTGATGAGGGAGTTGTACTACAAAGCGACATTGATACCTCATTAAAAACAGTAAAAATTA
ACGCACAAGAAAAGGGGCAACCTCTTCCTGATGAAGCAGTACTTCGTGAACAAGTACTAGAGAAACTCATTGTTGATACG
ATTCAAAGCCAGCAAGCTGAAAAAATGGGTATTCGTATTGATGATACTCGCCTTGAAGCTGCATTGAATGATATCGCAAA
AGAAAACAACATGACCTTAGCGCAGCTACAACAAAAAACAGCAGCTCAAGGACTTCCTTATGCCAATTTCCGCGAACAAA
TTCGTAAAGAAATAGCAGCAAGTGAAGCTCGTAATGCTCAAGTACGTCGCCGTATTAATATTCTTCCTCAAGAAGTAGAG
AGTCTTGCTCAGCTACTTGCAGAAGAAACTCAAGCAACAGTTCAATACAAAATCAGCCATATCCAGCTAAGAGTTGAAGA
TGGTGCAACTCAAGCAGATAAAGAAGCATTAGAAAAACAAGCTGAAGATCTTACAGAGCGATTAAAGCAAGGTGCTGATT
TTGCGACAATGGCTTACACCTACTCGAAAGGTCCAAAAGCTCTACAAGGTGGTGATTGGGGTTGGATGCGTAAAGAAGAA
ATGCCAACTATCTTTGCAGACCAAATTACCGGCCAAGGTAAAAACAGTATTATTGGTCCATTCCGTTCAGGCGTTGGTTT
CCATATATTAAAAATTGATGATGTGAAGGGACTTGAAACGGTTGCTGTAACAGAAGTAAATGCGCGTCATATTCTAATAA
AAACTTCAGTAATCATGAGTGATGAAGGTGCACAGCGTCTATTAAATACGATCATCGATGATATTAAATCAGGTAAAGAA
ACCTTTGCAGATATGGCACAACGTTATAGCCAAGACCCAGGCTCTGCTGCAAATGATGGTGAACTAGGTTTCCAAACTCC
GGATTTATACGTACCAGAATTTAAACACCAAGTTGAAACTCTACCTGTAGGTCAAATTAGCGCACCATTTAAAACGGTTC
ACGGCTGGCATATTGCTGAAGTATTAGAGCGTCGCCAAGTTGATAGAACTGATGCTGCGATGAAAAACAAAGCATACCGA
ATTCTTCTTAACCGTAAATTTAATGAAGAAGCTGGTGCATGGCTACAAGAAATCCGTGCAAGTGCTTATGTTGAAATCTT
ACAGGACGACGATGGTGAAGATGACAATGAATAA

Upstream 100 bases:

>100_bases
GACTACGGTCGCCCGTTCTACCTAAATAATTAATTATATGGAAATACATGAAGAGCCAACACTCTAAGGCTCTTCATTCT
CCTTACTCTTGGATGACACT

Downstream 100 bases:

>100_bases
TATTAAACGCATTGCGATCACTCCCGGCGAACCATCGGGTATTGGCCCAGATCTTGTTATTGCTATTGCTCAACAAGACT
GGCCTCATCAACTTGTCATT

Product: peptidyl-prolyl cis-trans isomerase (PPIase)

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKNWKFPLISTLLLLLTINVHAAPVELDRVVAIVDEGVVLQSDIDTSLKTVKINAQEKGQPLPDEAVLREQVLEKLIVDT
IQSQQAEKMGIRIDDTRLEAALNDIAKENNMTLAQLQQKTAAQGLPYANFREQIRKEIAASEARNAQVRRRINILPQEVE
SLAQLLAEETQATVQYKISHIQLRVEDGATQADKEALEKQAEDLTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEE
MPTIFADQITGQGKNSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKTSVIMSDEGAQRLLNTIIDDIKSGKE
TFADMAQRYSQDPGSAANDGELGFQTPDLYVPEFKHQVETLPVGQISAPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYR
ILLNRKFNEEAGAWLQEIRASAYVEILQDDDGEDDNE

Sequences:

>Translated_437_residues
MKNWKFPLISTLLLLLTINVHAAPVELDRVVAIVDEGVVLQSDIDTSLKTVKINAQEKGQPLPDEAVLREQVLEKLIVDT
IQSQQAEKMGIRIDDTRLEAALNDIAKENNMTLAQLQQKTAAQGLPYANFREQIRKEIAASEARNAQVRRRINILPQEVE
SLAQLLAEETQATVQYKISHIQLRVEDGATQADKEALEKQAEDLTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEE
MPTIFADQITGQGKNSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKTSVIMSDEGAQRLLNTIIDDIKSGKE
TFADMAQRYSQDPGSAANDGELGFQTPDLYVPEFKHQVETLPVGQISAPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYR
ILLNRKFNEEAGAWLQEIRASAYVEILQDDDGEDDNE
>Mature_437_residues
MKNWKFPLISTLLLLLTINVHAAPVELDRVVAIVDEGVVLQSDIDTSLKTVKINAQEKGQPLPDEAVLREQVLEKLIVDT
IQSQQAEKMGIRIDDTRLEAALNDIAKENNMTLAQLQQKTAAQGLPYANFREQIRKEIAASEARNAQVRRRINILPQEVE
SLAQLLAEETQATVQYKISHIQLRVEDGATQADKEALEKQAEDLTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEE
MPTIFADQITGQGKNSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKTSVIMSDEGAQRLLNTIIDDIKSGKE
TFADMAQRYSQDPGSAANDGELGFQTPDLYVPEFKHQVETLPVGQISAPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYR
ILLNRKFNEEAGAWLQEIRASAYVEILQDDDGEDDNE

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=430, Percent_Identity=49.0697674418605, Blast_Score=406, Evalue=1e-114,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_VIBF1 (Q5E863)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_203671.1
- HSSP:   Q9SL42
- ProteinModelPortal:   Q5E863
- SMR:   Q5E863
- STRING:   Q5E863
- GeneID:   3277834
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0288
- NMPDR:   fig|312309.3.peg.288
- eggNOG:   COG0760
- HOGENOM:   HBG391483
- OMA:   RHILIKT
- ProtClustDB:   CLSK873981
- BioCyc:   VFIS312309:VF0288-MONOMER
- HAMAP:   MF_01183
- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 48867; Mature: 48867

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNWKFPLISTLLLLLTINVHAAPVELDRVVAIVDEGVVLQSDIDTSLKTVKINAQEKGQ
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEECCCCCCEEEEEECHHHCCC
PLPDEAVLREQVLEKLIVDTIQSQQAEKMGIRIDDTRLEAALNDIAKENNMTLAQLQQKT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHH
AAQGLPYANFREQIRKEIAASEARNAQVRRRINILPQEVESLAQLLAEETQATVQYKISH
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEE
IQLRVEDGATQADKEALEKQAEDLTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEE
EEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHC
MPTIFADQITGQGKNSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKTSVIMS
CCCHHHHHHCCCCCCCCCCCHHCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEEEEEC
DEGAQRLLNTIIDDIKSGKETFADMAQRYSQDPGSAANDGELGFQTPDLYVPEFKHQVET
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LPVGQISAPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYRILLNRKFNEEAGAWLQEIRA
CCCCCCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
SAYVEILQDDDGEDDNE
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKNWKFPLISTLLLLLTINVHAAPVELDRVVAIVDEGVVLQSDIDTSLKTVKINAQEKGQ
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEECCCCCCEEEEEECHHHCCC
PLPDEAVLREQVLEKLIVDTIQSQQAEKMGIRIDDTRLEAALNDIAKENNMTLAQLQQKT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHH
AAQGLPYANFREQIRKEIAASEARNAQVRRRINILPQEVESLAQLLAEETQATVQYKISH
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEE
IQLRVEDGATQADKEALEKQAEDLTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEE
EEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHC
MPTIFADQITGQGKNSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKTSVIMS
CCCHHHHHHCCCCCCCCCCCHHCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEEEEEC
DEGAQRLLNTIIDDIKSGKETFADMAQRYSQDPGSAANDGELGFQTPDLYVPEFKHQVET
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LPVGQISAPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYRILLNRKFNEEAGAWLQEIRA
CCCCCCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
SAYVEILQDDDGEDDNE
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA