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The map label for this gene is secY [H]

Identifier: 59710864

GI number: 59710864

Start: 262401

End: 263732

Strand: Direct

Name: secY [H]

Synonym: VF_0257

Alternate gene names: 59710864

Gene position: 262401-263732 (Clockwise)

Preceding gene: 172087651

Following gene: 59710865

Centisome position: 9.06

GC content: 43.69

Gene sequence:

>1332_bases
ATGGCAAAGAAACCAGGAAAAGAAGTAAATAGTGCTCAGAGCGGCCTAGCTGAACTGAAATCGCGTCTGTTATTTGTTAT
AGGTGCGCTTTTAGTGTTCCGAGCAGGCTCATTTGTGCCAATTCCTGGGATTGACGCTGCTGTCCTTGCTGATCTTTTCG
AACAGCAGCAGGGTACCATCATTGAACTGTTTAACATGTTCTCTGGTGGTGCACTGTCGCGTGCCTCAATTCTAGCTCTA
GGTATTATGCCGTACATTTCGGCATCTATCGTTGTTCAGCTGTTAACAGTTGTTCATCCACCTCTAGCTGAATTGAAAAA
AGAAGGTGAGTCTGGTCGTCGTAAGATTAATCAGTACACACGTTATGGCACCTTGGTGCTGGCTACATTCCAAGCAATTG
GTATTGCAACCGGTCTACCAAGCATGATTCCAGGGTTAGTTGCTAACCCTGACATGATGTTCTATCTGACAGCTACAGTA
AGTTTAGTAACTGGTACCATGTTCTTAATGTGGTTAGGTGAACAAATTACTGAGCGTGGCATCGGTAACGGTATATCTTT
GATTATTTTCACAGGTATCGTTGCAGGTTTACCACCAGCTATCGGTGAAACGATCCAGCAGGCGCGTCAAGGTGAACTGC
ACGTGCTTCTTCTATTACTAATTGCAGTGATCTCATTTGCAGTTATCTACTTTGTAGTGTTCATGGAGCGTGGTCAACGT
CGTATCGTCGTTAACTATGCAAAACGTCAGCAAGGCCGTAAGGTATTTGCAGCTCAAAGTACTCACTTGCCACTTAAAAT
TAATATGGCTGGTGTGATTCCTGCAATTTTTGCATCAAGTATTATACTATTCCCTGGGACATTGGCTCAGTGGTTTGGTG
GTAACGGTGAAGGAACATTCGGTTGGTTAACTGATGTTTCAATGGCATTAAGTCCAGGTCAACCGTTATACGTAATGCTT
TATGCAGCAGCAATTATCTTCTTCTGTTTCTTCTATACTGCGTTGGTGTTTAACCCGCGTGAAACAGCTGATAACTTGAA
GAAGTCTGGTGCATTCGTACCCGGAATCCGCCCAGGTGAACAGACTACGAAATACATCGATAAAGTTATGACACGTCTAA
CCCTTGCTGGTGCGATGTACATTACCTTTATCTGTCTGATTCCCGAGTTTATGATGATCGCTTGGAACGTACGCTTCTAT
TTTGGCGGTACTTCCCTACTAATCGTAGTTGTTGTTATCATGGACTTTATGGCACAGGTTCAGACTCATCTGATGTCTCA
ACAGTATGAGTCCGTGTTGAAGAAGGCTAATCTGAAAGGCTACGGTCGTTAA

Upstream 100 bases:

>100_bases
CTGTAACTGTTAAAGGTCTACGCGTAACGAAAGGCGCTAAAGCTGCGATCGAAGCTGCAGGCGGTAAGATCGAGGAATAA
TCCTCGAAGGATGAGGTACA

Downstream 100 bases:

>100_bases
TTTCAGGTTCCAATTTTACGGAGTTTAGCAATGAAAGTTCGTGCTTCCGTTAAAAAAATCTGCCGCAACTGTAAAGTTAT
TAAGCGCAACGGTGTTGTGC

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MAKKPGKEVNSAQSGLAELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFEQQQGTIIELFNMFSGGALSRASILAL
GIMPYISASIVVQLLTVVHPPLAELKKEGESGRRKINQYTRYGTLVLATFQAIGIATGLPSMIPGLVANPDMMFYLTATV
SLVTGTMFLMWLGEQITERGIGNGISLIIFTGIVAGLPPAIGETIQQARQGELHVLLLLLIAVISFAVIYFVVFMERGQR
RIVVNYAKRQQGRKVFAAQSTHLPLKINMAGVIPAIFASSIILFPGTLAQWFGGNGEGTFGWLTDVSMALSPGQPLYVML
YAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTTKYIDKVMTRLTLAGAMYITFICLIPEFMMIAWNVRFY
FGGTSLLIVVVVIMDFMAQVQTHLMSQQYESVLKKANLKGYGR

Sequences:

>Translated_443_residues
MAKKPGKEVNSAQSGLAELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFEQQQGTIIELFNMFSGGALSRASILAL
GIMPYISASIVVQLLTVVHPPLAELKKEGESGRRKINQYTRYGTLVLATFQAIGIATGLPSMIPGLVANPDMMFYLTATV
SLVTGTMFLMWLGEQITERGIGNGISLIIFTGIVAGLPPAIGETIQQARQGELHVLLLLLIAVISFAVIYFVVFMERGQR
RIVVNYAKRQQGRKVFAAQSTHLPLKINMAGVIPAIFASSIILFPGTLAQWFGGNGEGTFGWLTDVSMALSPGQPLYVML
YAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTTKYIDKVMTRLTLAGAMYITFICLIPEFMMIAWNVRFY
FGGTSLLIVVVVIMDFMAQVQTHLMSQQYESVLKKANLKGYGR
>Mature_442_residues
AKKPGKEVNSAQSGLAELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFEQQQGTIIELFNMFSGGALSRASILALG
IMPYISASIVVQLLTVVHPPLAELKKEGESGRRKINQYTRYGTLVLATFQAIGIATGLPSMIPGLVANPDMMFYLTATVS
LVTGTMFLMWLGEQITERGIGNGISLIIFTGIVAGLPPAIGETIQQARQGELHVLLLLLIAVISFAVIYFVVFMERGQRR
IVVNYAKRQQGRKVFAAQSTHLPLKINMAGVIPAIFASSIILFPGTLAQWFGGNGEGTFGWLTDVSMALSPGQPLYVMLY
AAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTTKYIDKVMTRLTLAGAMYITFICLIPEFMMIAWNVRFYF
GGTSLLIVVVVIMDFMAQVQTHLMSQQYESVLKKANLKGYGR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=445, Percent_Identity=82.247191011236, Blast_Score=679, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48352; Mature: 48221

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKPGKEVNSAQSGLAELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFEQQQGTI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHH
IELFNMFSGGALSRASILALGIMPYISASIVVQLLTVVHPPLAELKKEGESGRRKINQYT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHH
RYGTLVLATFQAIGIATGLPSMIPGLVANPDMMFYLTATVSLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHHHCCHHHCCCHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
IGNGISLIIFTGIVAGLPPAIGETIQQARQGELHVLLLLLIAVISFAVIYFVVFMERGQR
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIVVNYAKRQQGRKVFAAQSTHLPLKINMAGVIPAIFASSIILFPGTLAQWFGGNGEGTF
EEEEEHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCH
GWLTDVSMALSPGQPLYVMLYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCH
QTTKYIDKVMTRLTLAGAMYITFICLIPEFMMIAWNVRFYFGGTSLLIVVVVIMDFMAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHH
QTHLMSQQYESVLKKANLKGYGR
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKKPGKEVNSAQSGLAELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFEQQQGTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHH
IELFNMFSGGALSRASILALGIMPYISASIVVQLLTVVHPPLAELKKEGESGRRKINQYT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHH
RYGTLVLATFQAIGIATGLPSMIPGLVANPDMMFYLTATVSLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHHHCCHHHCCCHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
IGNGISLIIFTGIVAGLPPAIGETIQQARQGELHVLLLLLIAVISFAVIYFVVFMERGQR
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIVVNYAKRQQGRKVFAAQSTHLPLKINMAGVIPAIFASSIILFPGTLAQWFGGNGEGTF
EEEEEHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCH
GWLTDVSMALSPGQPLYVMLYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCH
QTTKYIDKVMTRLTLAGAMYITFICLIPEFMMIAWNVRFYFGGTSLLIVVVVIMDFMAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHH
QTHLMSQQYESVLKKANLKGYGR
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]