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The map label for this gene is yeeO [C]

Identifier: 59710810

GI number: 59710810

Start: 225513

End: 227012

Strand: Reverse

Name: yeeO [C]

Synonym: VF_0203

Alternate gene names: 59710810

Gene position: 227012-225513 (Counterclockwise)

Preceding gene: 59710813

Following gene: 59710809

Centisome position: 7.83

GC content: 43.73

Gene sequence:

>1500_bases
GTGAGTACCCCTGAAACCTATAAGCGCAGCGCCCTGAATCCTGAAACCTCGCTTTTGCTCTTCCTCGTCCCTAATCCCTC
GAATCTCACCCCTATTTCCTATACACTAACCATCCCACCACCACACGAGAAAACCATGCTAGATAAACACGGTTTACTAA
CTCAACCTATCAGCGACGTGCTTCGTAAACTCACGACGCCTATGGTTTTTGGTATGGTTGCCATTCTGCTATTCAACTTG
GTGGATACCTTTTTTATCTCCTTGCTCGGCACCGATGCTTTAGCTGCAGTGAGTTTTACTTTCCCCGTCACCTTTGCAGT
AAACTGCATCACCATGGGGATTGGTGTTGGCTTATCAGCATCCATAGGTCATTTACTTGGTGAAGGCCATAGCAAACATG
CTGCAGAATTAACGACTCATGGGATAATCTTAGCCATCAGTTTAATTCTGATTGCTTGTGCTCTCGGGTTCTTCACCATC
GACCCACTCTTTACTCTTCTCGGTGCTGAAGACAAATTACTTCCTCTTATCGATGAATACATGTCTATTTGGTATCTAAC
CATACCTTTGCTCGTTATTCCGATGTCGAGCAATAGCGCAATTAGAGCCACAGGTGACACCAAAACCCCAGCAAAAATTA
TGATGCTAGCAGGGCTAATTAACGGCATTCTCGATCCACTGCTTATTTTTGGTTATGGCCCCTTCCCTGAGCTTGGAATT
CAAGGTGCTGCGATTGCAAGTGCGATTAGTTGGCTTGGTGCTCTTATCGCTTCATTCTATGTACTCACTCATAAAGTAAA
ACTGCTTGCTTTACCAAATAAAAATACACTTATTTCTGATTGGAAACAGATCTTAACCATCGGCTCCCCAGCCGCATTAT
CTAACGCGCTAAACCCAATATCGGGGGCTATTTTAATGATGATGCTTGCGAGCCAAGGGACCGTAGCTGTCGCCTCTTAT
GGTGCGGCACAACGCGTTGAATCATTAATGCTGCTGGTTATCATGGCATTAACGTCATCACTTAGCCCATTAGTGGCTCA
GAACCTAGGTGCAAAACAACCTGAACGTGTCAAAGAAGCAATATTTCTAGCCATTAAGTTCTCTGTCGCCTTTCAGCTCT
TTCTTTATATTCTGATTGTTCCACTTAGCATTCCAATCTCTCATTTATTTAGCCAAGACGATGCGGTTCAACACGGTTTG
TGGATGTACCTTATTTGCGTTCCATTTAGCTACGGCTTTCAAGGCATCGTTATGGTGTTAGTAAGTAGCTTAAATGCAAT
GAAAAAACCGTTATATTCTTTCAGTTGGAGTTTTATGAGGTTGTTTGTTTTTACATTACCAACCGCATGGATTGGCAGCC
AAATTTATGGAATGGAAGGATTATTTATCGGGATTGCAATGGGAAATGTGATGGGTGGTATTAGTGCGTTTTGGTATGCG
AGAACAAGAATCAGATTTGAGGACGCTGCACTCGAGGAGCGAGGAGACACGAAGAGCTAG

Upstream 100 bases:

>100_bases
GCTTTGATTTATTAATGGGGATGTAGGGGATTGATTGCAAGGGCTCTAGCGCTAATTTTTTGAAGAAGAAAAGAGGGTTC
AGGTTTCAGGAAGCTCAAAA

Downstream 100 bases:

>100_bases
GAAGAGCAGGTTTCAGGAAGATCAAAAGCAAGTCCCCCTGAAACCTAGCTCATCACCAACACCCCCTCCTAGCCTCCCCT
TATATCAACATCTCTAATCT

Product: Na(+) driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MSTPETYKRSALNPETSLLLFLVPNPSNLTPISYTLTIPPPHEKTMLDKHGLLTQPISDVLRKLTTPMVFGMVAILLFNL
VDTFFISLLGTDALAAVSFTFPVTFAVNCITMGIGVGLSASIGHLLGEGHSKHAAELTTHGIILAISLILIACALGFFTI
DPLFTLLGAEDKLLPLIDEYMSIWYLTIPLLVIPMSSNSAIRATGDTKTPAKIMMLAGLINGILDPLLIFGYGPFPELGI
QGAAIASAISWLGALIASFYVLTHKVKLLALPNKNTLISDWKQILTIGSPAALSNALNPISGAILMMMLASQGTVAVASY
GAAQRVESLMLLVIMALTSSLSPLVAQNLGAKQPERVKEAIFLAIKFSVAFQLFLYILIVPLSIPISHLFSQDDAVQHGL
WMYLICVPFSYGFQGIVMVLVSSLNAMKKPLYSFSWSFMRLFVFTLPTAWIGSQIYGMEGLFIGIAMGNVMGGISAFWYA
RTRIRFEDAALEERGDTKS

Sequences:

>Translated_499_residues
MSTPETYKRSALNPETSLLLFLVPNPSNLTPISYTLTIPPPHEKTMLDKHGLLTQPISDVLRKLTTPMVFGMVAILLFNL
VDTFFISLLGTDALAAVSFTFPVTFAVNCITMGIGVGLSASIGHLLGEGHSKHAAELTTHGIILAISLILIACALGFFTI
DPLFTLLGAEDKLLPLIDEYMSIWYLTIPLLVIPMSSNSAIRATGDTKTPAKIMMLAGLINGILDPLLIFGYGPFPELGI
QGAAIASAISWLGALIASFYVLTHKVKLLALPNKNTLISDWKQILTIGSPAALSNALNPISGAILMMMLASQGTVAVASY
GAAQRVESLMLLVIMALTSSLSPLVAQNLGAKQPERVKEAIFLAIKFSVAFQLFLYILIVPLSIPISHLFSQDDAVQHGL
WMYLICVPFSYGFQGIVMVLVSSLNAMKKPLYSFSWSFMRLFVFTLPTAWIGSQIYGMEGLFIGIAMGNVMGGISAFWYA
RTRIRFEDAALEERGDTKS
>Mature_498_residues
STPETYKRSALNPETSLLLFLVPNPSNLTPISYTLTIPPPHEKTMLDKHGLLTQPISDVLRKLTTPMVFGMVAILLFNLV
DTFFISLLGTDALAAVSFTFPVTFAVNCITMGIGVGLSASIGHLLGEGHSKHAAELTTHGIILAISLILIACALGFFTID
PLFTLLGAEDKLLPLIDEYMSIWYLTIPLLVIPMSSNSAIRATGDTKTPAKIMMLAGLINGILDPLLIFGYGPFPELGIQ
GAAIASAISWLGALIASFYVLTHKVKLLALPNKNTLISDWKQILTIGSPAALSNALNPISGAILMMMLASQGTVAVASYG
AAQRVESLMLLVIMALTSSLSPLVAQNLGAKQPERVKEAIFLAIKFSVAFQLFLYILIVPLSIPISHLFSQDDAVQHGLW
MYLICVPFSYGFQGIVMVLVSSLNAMKKPLYSFSWSFMRLFVFTLPTAWIGSQIYGMEGLFIGIAMGNVMGGISAFWYAR
TRIRFEDAALEERGDTKS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=383, Percent_Identity=23.7597911227154, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 54001; Mature: 53870

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPETYKRSALNPETSLLLFLVPNPSNLTPISYTLTIPPPHEKTMLDKHGLLTQPISDV
CCCCHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHHH
LRKLTTPMVFGMVAILLFNLVDTFFISLLGTDALAAVSFTFPVTFAVNCITMGIGVGLSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SIGHLLGEGHSKHAAELTTHGIILAISLILIACALGFFTIDPLFTLLGAEDKLLPLIDEY
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
MSIWYLTIPLLVIPMSSNSAIRATGDTKTPAKIMMLAGLINGILDPLLIFGYGPFPELGI
HHHHHHHHHHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QGAAIASAISWLGALIASFYVLTHKVKLLALPNKNTLISDWKQILTIGSPAALSNALNPI
CHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHCCCHH
SGAILMMMLASQGTVAVASYGAAQRVESLMLLVIMALTSSLSPLVAQNLGAKQPERVKEA
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHH
IFLAIKFSVAFQLFLYILIVPLSIPISHLFSQDDAVQHGLWMYLICVPFSYGFQGIVMVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
VSSLNAMKKPLYSFSWSFMRLFVFTLPTAWIGSQIYGMEGLFIGIAMGNVMGGISAFWYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHEEHHHHHHHHHHHHHHHHH
RTRIRFEDAALEERGDTKS
HHHEEEHHHHHHCCCCCCC
>Mature Secondary Structure 
STPETYKRSALNPETSLLLFLVPNPSNLTPISYTLTIPPPHEKTMLDKHGLLTQPISDV
CCCHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHHH
LRKLTTPMVFGMVAILLFNLVDTFFISLLGTDALAAVSFTFPVTFAVNCITMGIGVGLSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SIGHLLGEGHSKHAAELTTHGIILAISLILIACALGFFTIDPLFTLLGAEDKLLPLIDEY
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
MSIWYLTIPLLVIPMSSNSAIRATGDTKTPAKIMMLAGLINGILDPLLIFGYGPFPELGI
HHHHHHHHHHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QGAAIASAISWLGALIASFYVLTHKVKLLALPNKNTLISDWKQILTIGSPAALSNALNPI
CHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHCCCHH
SGAILMMMLASQGTVAVASYGAAQRVESLMLLVIMALTSSLSPLVAQNLGAKQPERVKEA
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHH
IFLAIKFSVAFQLFLYILIVPLSIPISHLFSQDDAVQHGLWMYLICVPFSYGFQGIVMVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
VSSLNAMKKPLYSFSWSFMRLFVFTLPTAWIGSQIYGMEGLFIGIAMGNVMGGISAFWYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHEEHHHHHHHHHHHHHHHHH
RTRIRFEDAALEERGDTKS
HHHEEEHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]