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The map label for this gene is glnL [H]

Identifier: 59710703

GI number: 59710703

Start: 112415

End: 113473

Strand: Reverse

Name: glnL [H]

Synonym: VF_0096

Alternate gene names: 59710703

Gene position: 113473-112415 (Counterclockwise)

Preceding gene: 59710704

Following gene: 59710702

Centisome position: 3.92

GC content: 40.89

Gene sequence:

>1059_bases
ATGATGGCGTTAACGATGGATTTCTCAACTCAATTACTCGAACACCAAGTTACAGCAATTTTATTGCTCGATGATCAACG
TCAAATTCATTATGCCAATCCTGCGGCTGAGCAACTGTTCTCTCAGAGTGCTCAGCGTATGGCTCAACACGCCTTTGATG
ATTTATTTCACTCTCCGCAATTTGATTTATCCACTCTCATGCTGCCATTGAACACAGGACAAAGTGTGACTGACAGTGAT
GTTCGTATCATGATTGATGAACAACCACTTTATATCGAGCTAACTTCTAGCCCAGTTGCTATCAATAAATCCCTCTATTT
ATTGGTTGAAATTCGTCAAATAGAGCAGCAAAGACGCCTATCTCAAGAGATTAATCAACACGCACAACAACAAGCCGCAA
AGGTTCTTGTTCGTAGCTTAGCGCATGAAATTAAAAATCCATTAGGCGGTTTGCGTGGAGCGGCACAATTACTAGAACGT
ATGCTGCCTGAACGTGAACTTCATGAATATACTCAAATCATTATTGAACAAGCAGACCGTCTACGAAATTTAGTCGACCG
TTTACTGGGTCCTCAAAAGCTCGGAACAAAACAGCCAGAAAACTTGCACGCTATCATTGAAAAAGTTCGCCAACTCATTG
AATTAAATTCATCTTATCAAGTAAAAATCATTCGAGATTACGACCCAAGCCTACCCGATTTTGACGTAGATGCGGAGCAA
ATAGAGCAAGCCATTCTCAATATCGTAAGTAATGCAGCTGAAGTTCTTAAAGACCAACCTGACGGTACGATTACCTTAAA
AACCAGAACGGATTTCCAAACCAACATCTATGGTCAACGTCATAAACTCGCAGCAAAAATAGACATTATTGATAATGGCC
CTGGGATCCCTAGCCACATCCAAGATACGCTTTTTTATCCTATGGTTAGTGCTCGTGAAGGCGGTACAGGATTGGGATTA
TCTATCTCGCAAAATTTAATCGATCAGCATAATGGGAAAATAGATGTCTCTAGCTGGCCGGGAAAAACCATTTTCACCAT
TTACCTCCCTCTCAAATAA

Upstream 100 bases:

>100_bases
CTACACCGACCGTCTGCAAACTAGAGGAATTCATATAGTTCCATTCTAAAAAGCAAGGTATGATGCACCATGATGGTGCA
TTTATTAATTTGCTATAAGG

Downstream 100 bases:

>100_bases
AAATAACCTCACAAAAGGGATAACGGAGAAGCAAAATTATGAGTAAAGGATTTATCTGGGTTGTTGATGATGACAGCTCA
ATTCGCTGGGTATTAGAAAA

Product: nitrogen regulation protein NR(II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MMALTMDFSTQLLEHQVTAILLLDDQRQIHYANPAAEQLFSQSAQRMAQHAFDDLFHSPQFDLSTLMLPLNTGQSVTDSD
VRIMIDEQPLYIELTSSPVAINKSLYLLVEIRQIEQQRRLSQEINQHAQQQAAKVLVRSLAHEIKNPLGGLRGAAQLLER
MLPERELHEYTQIIIEQADRLRNLVDRLLGPQKLGTKQPENLHAIIEKVRQLIELNSSYQVKIIRDYDPSLPDFDVDAEQ
IEQAILNIVSNAAEVLKDQPDGTITLKTRTDFQTNIYGQRHKLAAKIDIIDNGPGIPSHIQDTLFYPMVSAREGGTGLGL
SISQNLIDQHNGKIDVSSWPGKTIFTIYLPLK

Sequences:

>Translated_352_residues
MMALTMDFSTQLLEHQVTAILLLDDQRQIHYANPAAEQLFSQSAQRMAQHAFDDLFHSPQFDLSTLMLPLNTGQSVTDSD
VRIMIDEQPLYIELTSSPVAINKSLYLLVEIRQIEQQRRLSQEINQHAQQQAAKVLVRSLAHEIKNPLGGLRGAAQLLER
MLPERELHEYTQIIIEQADRLRNLVDRLLGPQKLGTKQPENLHAIIEKVRQLIELNSSYQVKIIRDYDPSLPDFDVDAEQ
IEQAILNIVSNAAEVLKDQPDGTITLKTRTDFQTNIYGQRHKLAAKIDIIDNGPGIPSHIQDTLFYPMVSAREGGTGLGL
SISQNLIDQHNGKIDVSSWPGKTIFTIYLPLK
>Mature_352_residues
MMALTMDFSTQLLEHQVTAILLLDDQRQIHYANPAAEQLFSQSAQRMAQHAFDDLFHSPQFDLSTLMLPLNTGQSVTDSD
VRIMIDEQPLYIELTSSPVAINKSLYLLVEIRQIEQQRRLSQEINQHAQQQAAKVLVRSLAHEIKNPLGGLRGAAQLLER
MLPERELHEYTQIIIEQADRLRNLVDRLLGPQKLGTKQPENLHAIIEKVRQLIELNSSYQVKIIRDYDPSLPDFDVDAEQ
IEQAILNIVSNAAEVLKDQPDGTITLKTRTDFQTNIYGQRHKLAAKIDIIDNGPGIPSHIQDTLFYPMVSAREGGTGLGL
SISQNLIDQHNGKIDVSSWPGKTIFTIYLPLK

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=352, Percent_Identity=52.5568181818182, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1788549, Length=352, Percent_Identity=26.1363636363636, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=29.2682926829268, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=27.3109243697479, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=360, Percent_Identity=25, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=309, Percent_Identity=25.8899676375405, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=25.0936329588015, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=26.0869565217391, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=254, Percent_Identity=24.8031496062992, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789808, Length=308, Percent_Identity=23.7012987012987, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39779; Mature: 39779

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMALTMDFSTQLLEHQVTAILLLDDQRQIHYANPAAEQLFSQSAQRMAQHAFDDLFHSPQ
CEEEEECHHHHHHHHHCEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC
FDLSTLMLPLNTGQSVTDSDVRIMIDEQPLYIELTSSPVAINKSLYLLVEIRQIEQQRRL
CCCEEEEEECCCCCCCCCCCCEEEEECCCEEEEECCCCEEECCCEEEEHHHHHHHHHHHH
SQEINQHAQQQAAKVLVRSLAHEIKNPLGGLRGAAQLLERMLPERELHEYTQIIIEQADR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LRNLVDRLLGPQKLGTKQPENLHAIIEKVRQLIELNSSYQVKIIRDYDPSLPDFDVDAEQ
HHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHH
IEQAILNIVSNAAEVLKDQPDGTITLKTRTDFQTNIYGQRHKLAAKIDIIDNGPGIPSHI
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHEEEEEEEEEECCCCCCHHH
QDTLFYPMVSAREGGTGLGLSISQNLIDQHNGKIDVSSWPGKTIFTIYLPLK
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECC
>Mature Secondary Structure
MMALTMDFSTQLLEHQVTAILLLDDQRQIHYANPAAEQLFSQSAQRMAQHAFDDLFHSPQ
CEEEEECHHHHHHHHHCEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC
FDLSTLMLPLNTGQSVTDSDVRIMIDEQPLYIELTSSPVAINKSLYLLVEIRQIEQQRRL
CCCEEEEEECCCCCCCCCCCCEEEEECCCEEEEECCCCEEECCCEEEEHHHHHHHHHHHH
SQEINQHAQQQAAKVLVRSLAHEIKNPLGGLRGAAQLLERMLPERELHEYTQIIIEQADR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LRNLVDRLLGPQKLGTKQPENLHAIIEKVRQLIELNSSYQVKIIRDYDPSLPDFDVDAEQ
HHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHH
IEQAILNIVSNAAEVLKDQPDGTITLKTRTDFQTNIYGQRHKLAAKIDIIDNGPGIPSHI
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHEEEEEEEEEECCCCCCHHH
QDTLFYPMVSAREGGTGLGLSISQNLIDQHNGKIDVSSWPGKTIFTIYLPLK
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2574025 [H]