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The map label for this gene is ywlC [H]

Identifier: 58617022

GI number: 58617022

Start: 491814

End: 492413

Strand: Reverse

Name: ywlC [H]

Synonym: ERGA_CDS_02950

Alternate gene names: 58617022

Gene position: 492413-491814 (Counterclockwise)

Preceding gene: 58617024

Following gene: 58617021

Centisome position: 32.83

GC content: 26.67

Gene sequence:

>600_bases
ATGATATCAAAAGCAGTAGAAGCACTTAAAAATAAACAACTTATATGCTTCCCTACTGAAACTGTTTATGCATTAGCTGG
AGATGCATACAGTATTGAAGTAATACAAAAAATATACAAAATAAAAAACAGACCATATAACAAACCAGTATCACTATTAC
TAAGCAATATAGATCAAATAAAGCAGTTTTCTAATCTGACAGAACATACTGCCTATATAATACAAGAACTATCTCCAGGG
CCTATTACTTTTATACTACCAATACACAATTATGGTAAATTACCAAAACAATTTTTTTATAATAAGATTGGAATACGCAT
CCCAAATCATCCAATAGCTTTAGCAATTTTAAATAATTTTGATCATCCAATAACAGCAACAAGTGTTAATATATCTGGAC
AACAAGATGCAACTAGTGTTGATCAAATATCAGATAATATTAAAAAAAACATTTCTTTTATAATAGATAATAATAGGTTA
GTTCATGGAACTGCATCAACAGTGATTGATCTCACTTCATATAAAATATTAAGAAAAGGTGCAGTAACAAAACAAAAAAT
TCAAGAAATATTAAAAAAAATTAATATAATACTTCCATAA

Upstream 100 bases:

>100_bases
TAGAGAAAAATACATAATTTTCGTCATTTACTAATACTAGTACATTTACATTATCCTACATATAATTTTAAACCTACTAC
ATAATAAATATAGGCACATT

Downstream 100 bases:

>100_bases
AATAAATATATTATTTCCTTAATAAAAAAAACAGATTCAGAAGATTTACTTTTAATCGATATTTTAGCTTTATTTTCTTT
AATACAAGAAGTTTACTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MISKAVEALKNKQLICFPTETVYALAGDAYSIEVIQKIYKIKNRPYNKPVSLLLSNIDQIKQFSNLTEHTAYIIQELSPG
PITFILPIHNYGKLPKQFFYNKIGIRIPNHPIALAILNNFDHPITATSVNISGQQDATSVDQISDNIKKNISFIIDNNRL
VHGTASTVIDLTSYKILRKGAVTKQKIQEILKKINIILP

Sequences:

>Translated_199_residues
MISKAVEALKNKQLICFPTETVYALAGDAYSIEVIQKIYKIKNRPYNKPVSLLLSNIDQIKQFSNLTEHTAYIIQELSPG
PITFILPIHNYGKLPKQFFYNKIGIRIPNHPIALAILNNFDHPITATSVNISGQQDATSVDQISDNIKKNISFIIDNNRL
VHGTASTVIDLTSYKILRKGAVTKQKIQEILKKINIILP
>Mature_199_residues
MISKAVEALKNKQLICFPTETVYALAGDAYSIEVIQKIYKIKNRPYNKPVSLLLSNIDQIKQFSNLTEHTAYIIQELSPG
PITFILPIHNYGKLPKQFFYNKIGIRIPNHPIALAILNNFDHPITATSVNISGQQDATSVDQISDNIKKNISFIIDNNRL
VHGTASTVIDLTSYKILRKGAVTKQKIQEILKKINIILP

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=209, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI2367210, Length=145, Percent_Identity=26.8965517241379, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI87081864, Length=186, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537239, Length=196, Percent_Identity=29.0816326530612, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6321269, Length=194, Percent_Identity=31.4432989690722, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI78707274, Length=193, Percent_Identity=33.160621761658, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 22367; Mature: 22367

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKAVEALKNKQLICFPTETVYALAGDAYSIEVIQKIYKIKNRPYNKPVSLLLSNIDQI
CCHHHHHHHHCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KQFSNLTEHTAYIIQELSPGPITFILPIHNYGKLPKQFFYNKIGIRIPNHPIALAILNNF
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCEEECCCCEEEEEECCC
DHPITATSVNISGQQDATSVDQISDNIKKNISFIIDNNRLVHGTASTVIDLTSYKILRKG
CCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCEEEEECHHHHHHHHHHHHHHHC
AVTKQKIQEILKKINIILP
CCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MISKAVEALKNKQLICFPTETVYALAGDAYSIEVIQKIYKIKNRPYNKPVSLLLSNIDQI
CCHHHHHHHHCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KQFSNLTEHTAYIIQELSPGPITFILPIHNYGKLPKQFFYNKIGIRIPNHPIALAILNNF
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCEEECCCCEEEEEECCC
DHPITATSVNISGQQDATSVDQISDNIKKNISFIIDNNRLVHGTASTVIDLTSYKILRKG
CCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCEEEEECHHHHHHHHHHHHHHHC
AVTKQKIQEILKKINIILP
CCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]