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The map label for this gene is engD [H]

Identifier: 58616821

GI number: 58616821

Start: 156165

End: 157256

Strand: Reverse

Name: engD [H]

Synonym: ERGA_CDS_00940

Alternate gene names: 58616821

Gene position: 157256-156165 (Counterclockwise)

Preceding gene: 58616822

Following gene: 58616819

Centisome position: 10.48

GC content: 32.33

Gene sequence:

>1092_bases
ATGGGATTAAATTGTGGAATTGTTGGTCTGCCTAATGTAGGAAAATCAACTTTATTTAATGCATTAACATGTACTACAGT
AGCAGAAGTTGCAAATTATCCATTTTGTACAATAGAACCTAATATAGGTAAAGCACTAGTAAAAGATGATAGATTAAAGA
CCTTAGCACAAATGGCATCATCCAAAAAAATCATATACAATCAGGTTGAATGCGTTGACATCGCAGGATTAGTCAGCGGA
GCAAGCAATGGTGAAGGGTTAGGTAACAAATTTTTAAGTCACATAAGAGAAGTAGATGCCATTATTCATGTACTACGTTG
TTTTAGTGATCAAAACATTAGTCATGTAAATCAATCTATAGATCCAATAGGTGATGCGGAAATTGTAGAAATGGAACTCA
TTTTAGCAGATATTGAGAGTTTAAAACGTCGTCTAATTACTATGGAAAAAGCAGTAAAAGCGAATAAAGAACCCAAAAAA
AAGCTAGATAATATGTTAGAAGTACTTAGTATTCTAGAAGCTGGAAATTTAGCAAAAAATGCACAACATATAGATAATAA
TGAATTAAAACAATTGAATCTCATCACTACAAAACCTATGATGTATGTGTGCAATGTAGAAGAATCAAATGTTATAACTG
GAAACACTCTATCAGAAAAAGTAAAGATAATGGCAAAAAATAACAATAACAAATTCTGTTGCATATCAGCTAAATTAGAA
GCAGACGTTGCAAGCTTAGATACAGAAGAAGAAAAACTATCCTTTTTAGCTGAGTTTAACCTAAAAGAGGCAGGTACAAC
ATCAGTAGTAAAGACTATGTATGAATTACTTGACATGATTACTTTCTTTACACTAGGACCACAAGAAGCACGTGCTTGGC
CTATAAAAAGGTTATCCACAGCAAGTACTGCAGCTGGAGTAATTCATACCGACTTTGAAAAAGGCTTTATAAAAGCAGAG
TTAATTAGCTTTGATGATTATATTAAATATAACGGAGAGGCAAAATGTAAAGAAGCTGGAAAAGTCAGATTTGAAGGCAG
AGATTATATAGTACAAGATGGTGACATAATACACTTTAGACATAGTAATTAA

Upstream 100 bases:

>100_bases
TTACCTGTTATAAGTAATTTTCATACCTTGTAATTTATCAGTACCATTGCTAAATGATTAATGATACAATCTTCATGTTA
TAATTCATTTAACTATCACT

Downstream 100 bases:

>100_bases
GTTACCAATTGGTTATCTATAAAATTATTTATCATACACCACTTAAATATCTTTGATCTATTACCCAACAACAATATTTT
ATTAAATGAAATGAATTCCA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGLNCGIVGLPNVGKSTLFNALTCTTVAEVANYPFCTIEPNIGKALVKDDRLKTLAQMASSKKIIYNQVECVDIAGLVSG
ASNGEGLGNKFLSHIREVDAIIHVLRCFSDQNISHVNQSIDPIGDAEIVEMELILADIESLKRRLITMEKAVKANKEPKK
KLDNMLEVLSILEAGNLAKNAQHIDNNELKQLNLITTKPMMYVCNVEESNVITGNTLSEKVKIMAKNNNNKFCCISAKLE
ADVASLDTEEEKLSFLAEFNLKEAGTTSVVKTMYELLDMITFFTLGPQEARAWPIKRLSTASTAAGVIHTDFEKGFIKAE
LISFDDYIKYNGEAKCKEAGKVRFEGRDYIVQDGDIIHFRHSN

Sequences:

>Translated_363_residues
MGLNCGIVGLPNVGKSTLFNALTCTTVAEVANYPFCTIEPNIGKALVKDDRLKTLAQMASSKKIIYNQVECVDIAGLVSG
ASNGEGLGNKFLSHIREVDAIIHVLRCFSDQNISHVNQSIDPIGDAEIVEMELILADIESLKRRLITMEKAVKANKEPKK
KLDNMLEVLSILEAGNLAKNAQHIDNNELKQLNLITTKPMMYVCNVEESNVITGNTLSEKVKIMAKNNNNKFCCISAKLE
ADVASLDTEEEKLSFLAEFNLKEAGTTSVVKTMYELLDMITFFTLGPQEARAWPIKRLSTASTAAGVIHTDFEKGFIKAE
LISFDDYIKYNGEAKCKEAGKVRFEGRDYIVQDGDIIHFRHSN
>Mature_362_residues
GLNCGIVGLPNVGKSTLFNALTCTTVAEVANYPFCTIEPNIGKALVKDDRLKTLAQMASSKKIIYNQVECVDIAGLVSGA
SNGEGLGNKFLSHIREVDAIIHVLRCFSDQNISHVNQSIDPIGDAEIVEMELILADIESLKRRLITMEKAVKANKEPKKK
LDNMLEVLSILEAGNLAKNAQHIDNNELKQLNLITTKPMMYVCNVEESNVITGNTLSEKVKIMAKNNNNKFCCISAKLEA
DVASLDTEEEKLSFLAEFNLKEAGTTSVVKTMYELLDMITFFTLGPQEARAWPIKRLSTASTAAGVIHTDFEKGFIKAEL
ISFDDYIKYNGEAKCKEAGKVRFEGRDYIVQDGDIIHFRHSN

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=367, Percent_Identity=41.6893732970027, Blast_Score=254, Evalue=6e-68,
Organism=Homo sapiens, GI58761502, Length=214, Percent_Identity=35.5140186915888, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI111955139, Length=116, Percent_Identity=31.8965517241379, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787454, Length=362, Percent_Identity=47.2375690607735, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI1789574, Length=177, Percent_Identity=28.2485875706215, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=369, Percent_Identity=40.1084010840108, Blast_Score=246, Evalue=9e-66,
Organism=Saccharomyces cerevisiae, GI6319499, Length=375, Percent_Identity=38.4, Blast_Score=241, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=34.9081364829396, Blast_Score=199, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6321649, Length=162, Percent_Identity=36.4197530864198, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640873, Length=366, Percent_Identity=40.1639344262295, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24640877, Length=366, Percent_Identity=40.1639344262295, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24640875, Length=366, Percent_Identity=40.1639344262295, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24640879, Length=322, Percent_Identity=37.888198757764, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24585318, Length=140, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40130; Mature: 39998

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLNCGIVGLPNVGKSTLFNALTCTTVAEVANYPFCTIEPNIGKALVKDDRLKTLAQMAS
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHC
SKKIIYNQVECVDIAGLVSGASNGEGLGNKFLSHIREVDAIIHVLRCFSDQNISHVNQSI
CCCHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
DPIGDAEIVEMELILADIESLKRRLITMEKAVKANKEPKKKLDNMLEVLSILEAGNLAKN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHH
AQHIDNNELKQLNLITTKPMMYVCNVEESNVITGNTLSEKVKIMAKNNNNKFCCISAKLE
HHHCCCCCHHEEEEEEECCEEEEEECCCCCEEECCCCCCEEEEEEECCCCEEEEEEECCC
ADVASLDTEEEKLSFLAEFNLKEAGTTSVVKTMYELLDMITFFTLGPQEARAWPIKRLST
CHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCC
ASTAAGVIHTDFEKGFIKAELISFDDYIKYNGEAKCKEAGKVRFEGRDYIVQDGDIIHFR
CHHHCCEEEECCHHCCEEEEEECCHHHEEECCCCCCCCCCCEEECCCEEEEECCCEEEEE
HSN
CCC
>Mature Secondary Structure 
GLNCGIVGLPNVGKSTLFNALTCTTVAEVANYPFCTIEPNIGKALVKDDRLKTLAQMAS
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHC
SKKIIYNQVECVDIAGLVSGASNGEGLGNKFLSHIREVDAIIHVLRCFSDQNISHVNQSI
CCCHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
DPIGDAEIVEMELILADIESLKRRLITMEKAVKANKEPKKKLDNMLEVLSILEAGNLAKN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHH
AQHIDNNELKQLNLITTKPMMYVCNVEESNVITGNTLSEKVKIMAKNNNNKFCCISAKLE
HHHCCCCCHHEEEEEEECCEEEEEECCCCCEEECCCCCCEEEEEEECCCCEEEEEEECCC
ADVASLDTEEEKLSFLAEFNLKEAGTTSVVKTMYELLDMITFFTLGPQEARAWPIKRLST
CHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCC
ASTAAGVIHTDFEKGFIKAELISFDDYIKYNGEAKCKEAGKVRFEGRDYIVQDGDIIHFR
CHHHCCEEEECCHHCCEEEEEECCHHHEEECCCCCCCCCCCEEECCCEEEEECCCEEEEE
HSN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]